Clinical trial · Observational
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma
A COG Soft Tissue Sarcoma Diagnosis, Biology and Banking Protocol
NCT00919269CI-TRIAL-00070134completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to collect and store tumor tissue, blood, and bone marrow samples from patients with soft tissue sarcoma that will be tested in the laboratory. Collecting and storing samples of tumor tissue, blood, and bone marrow from patients to test in the laboratory may help the study of cancer.
Conditions
Conditions (16)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adult Rhabdomyosarcoma | Adult Rhabdomyosarcoma | ONTOLOGY_EXACT | 0.98 |
| Childhood Desmoplastic Small Round Cell Tumor | Childhood Desmoplastic Small Round Cell Tumor | ONTOLOGY_EXACT | 0.98 |
| Chordoma | Chordoma | ONTOLOGY_EXACT | 0.98 |
| Desmoid-Type Fibromatosis | Desmoid Fibromatosis | ALIAS | 0.90 |
| Metastatic Childhood Soft Tissue Sarcoma | Childhood Soft Tissue Sarcoma | CURATED_BROADER | 0.78 |
| Non-Metastatic Childhood Soft Tissue Sarcoma | — | UNRESOLVED | — |
| Previously Treated Childhood Rhabdomyosarcoma | Childhood Rhabdomyosarcoma | CURATED_BROADER | 0.78 |
| Recurrent Adult Soft Tissue Sarcoma | Adult Soft Tissue Sarcoma | CURATED_BROADER | 0.78 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cytology Specimen Collection Procedure | Other | — | UNRESOLVED |
| Laboratory Biomarker Analysis | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Ancillary-Correlative (specimen collection)
- description
- Surgical tissue, bone marrow, and blood specimens are collected at diagnosis (initial or relapse) and, if applicable, at the development of a second primary tumor. Specimens are used for research purposes. A certificate of confidentiality protecting the identity of research participants in this project has been issued by the National Cancer Institute.
- interventionNames
- Other: Cytology Specimen Collection Procedure
- Other: Laboratory Biomarker Analysis
Primary outcomes (2)
- measure
- Collection of human tumor tissue and other biological specimens (blood, serum, and bone marrow) from patients with rhabdomyosarcoma or non-rhabdomyosarcoma soft tissue sarcoma
- timeFrame
- Up to 10 years
- measure
- Collection of clinical data on patients who are not being treated on a COG therapeutic study
- timeFrame
- Up to 10 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria:
* Histologically or cytologically confirmed diagnosis of 1 of the following:
* Rhabdomyosarcoma
* Non-rhabdomyosarcoma soft tissue sarcoma
* Chordoma
* Desmoid fibromatosis
* Desmoplastic round cell tumors
* Undifferentiated embryonal sarcoma of the liver
* Unclassified soft tissue sarcoma that is too undifferentiated to be placed in a specific pathologic category in the WHO classification (often called ?undifferentiated soft tissue sarcoma? or ?soft tissue sarcoma NOS?)
* Other soft tissue neoplasms, excluding benign tumors
* Must have pathological specimens of tumor-containing tissue or bone marrow (beyond that needed by the institution for diagnosis) available for study
* No malignant rhabdoid tumor, Ewing sarcoma/primitive neuroectodermal tumor, or osteogenic sarcoma of bone
* No osteogenic sarcomaReferences
Publications (0)
Data not yet available
No reference posted for this study.