Cancer Family
Hematopoietic and Lymphoid Cell Neoplasm
CI-CAN-00000023Explore in graph →
HematologicNon-malignant4,232 active trials98 approved drugs1,009 evidence items
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Cancer Family
CI-CAN-00000023Explore in graph →
Genomics
60 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
150 cases with simple somatic mutation data · 1,025 cases total · 2026-01-05 · mapped to Acute Myeloid Leukemia EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | NRAS | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 22 |
| 150 |
| 14.7% |
| cbioportal |
| 2 | KIT | Ssm | 15 | 150 | 10% | cbioportal |
| 3 | FLT3 | Ssm | 10 | 150 | 6.7% | cbioportal |
| 5 | PTPN11 | Ssm | 9 | 150 | 6% | cbioportal |
| 4 | KRAS | Ssm | 9 | 150 | 6% | cbioportal |
| 6 | TET2 | Ssm | 5 | 150 | 3.3% | cbioportal |
| 7 | WT1 | Ssm | 5 | 150 | 3.3% | cbioportal |
| 8 | CCND2 | Ssm | 4 | 150 | 2.7% | cbioportal |
| 9 | CDK11A | Ssm | 4 | 150 | 2.7% | cbioportal |
| 13 | SLX9 | Ssm | 4 | 150 | 2.7% | cbioportal |
| 11 | IDH2 | Ssm | 4 | 150 | 2.7% | cbioportal |
| 10 | GATA2 | Ssm | 4 | 150 | 2.7% | cbioportal |
| 12 | IKZF1 | Ssm | 4 | 150 | 2.7% | cbioportal |
| 17 | SMC3 | Ssm | 3 | 150 | 2% | cbioportal |
| 14 | AKAP9 | Ssm | 3 | 150 | 2% | cbioportal |
| 15 | HLA-DQA1 | Ssm | 3 | 150 | 2% | cbioportal |
| 16 | NOM1 | Ssm | 3 | 150 | 2% | cbioportal |
| 18 | SORD | Ssm | 3 | 150 | 2% | cbioportal |
| 28 | HLA-C | Ssm | 2 | 150 | 1.3% | cbioportal |
| 40 | WDR18 | Ssm | 2 | 150 | 1.3% | cbioportal |
| 19 | ARRDC3 | Ssm | 2 | 150 | 1.3% | cbioportal |
| 25 | DHX15 | Ssm | 2 | 150 | 1.3% | cbioportal |
| 20 | CITED4 | Ssm | 2 | 150 | 1.3% | cbioportal |
| 32 | KMT2D | Ssm | 2 | 150 | 1.3% | cbioportal |
| 24 | CWC27 | Ssm | 2 | 150 | 1.3% | cbioportal |
| 34 | MYC | Ssm | 2 | 150 | 1.3% | cbioportal |
| 26 | EP300 | Ssm | 2 | 150 | 1.3% | cbioportal |
| 23 | CTSH | Ssm | 2 | 150 | 1.3% | cbioportal |
| 35 | PCNT | Ssm | 2 | 150 | 1.3% | cbioportal |
| 36 | POLR3B | Ssm | 2 | 150 | 1.3% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05