Cancer Family
Hematopoietic and Lymphatic System Neoplasm
CI-CAN-00000022Explore in graph →
Non-malignant4,305 active trials98 approved drugs1,010 evidence items
- NCIt
- C35813
Loading cancer entity…
Cancer Family
CI-CAN-00000022Explore in graph →
Genomics
60 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
48 cases with simple somatic mutation data · 48 cases total · 2026-01-07 · mapped to Diffuse Large B-Cell Lymphoma Unclassifiable EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | IGLL5 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 17 |
| 48 |
| 35.4% |
| cbioportal |
| 2 | MUC4 | Ssm | 15 | 48 | 31.3% | cbioportal |
| 3 | KMT2D | Ssm | 14 | 48 | 29.2% | cbioportal |
| 4 | MUC2 | Ssm | 14 | 48 | 29.2% | cbioportal |
| 6 | BTG2 | Ssm | 13 | 48 | 27.1% | cbioportal |
| 5 | B2M | Ssm | 13 | 48 | 27.1% | cbioportal |
| 7 | MUC16 | Ssm | 11 | 48 | 22.9% | cbioportal |
| 9 | FAT4 | Ssm | 10 | 48 | 20.8% | cbioportal |
| 8 | CARD11 | Ssm | 10 | 48 | 20.8% | cbioportal |
| 12 | TTN | Ssm | 10 | 48 | 20.8% | cbioportal |
| 10 | PIM1 | Ssm | 10 | 48 | 20.8% | cbioportal |
| 11 | SYNE1 | Ssm | 10 | 48 | 20.8% | cbioportal |
| 14 | MUC5B | Ssm | 9 | 48 | 18.8% | cbioportal |
| 13 | H1-4 | Ssm | 9 | 48 | 18.8% | cbioportal |
| 16 | P2RY8 | Ssm | 8 | 48 | 16.7% | cbioportal |
| 15 | CSMD3 | Ssm | 8 | 48 | 16.7% | cbioportal |
| 17 | PCLO | Ssm | 8 | 48 | 16.7% | cbioportal |
| 27 | MUC17 | Ssm | 7 | 48 | 14.6% | cbioportal |
| 33 | ZFHX4 | Ssm | 7 | 48 | 14.6% | cbioportal |
| 30 | RHPN2 | Ssm | 7 | 48 | 14.6% | cbioportal |
| 26 | LRP2 | Ssm | 7 | 48 | 14.6% | cbioportal |
| 29 | OBSCN | Ssm | 7 | 48 | 14.6% | cbioportal |
| 28 | MYD88 | Ssm | 7 | 48 | 14.6% | cbioportal |
| 23 | HLA-C | Ssm | 7 | 48 | 14.6% | cbioportal |
| 19 | BTG1 | Ssm | 7 | 48 | 14.6% | cbioportal |
| 31 | STAT3 | Ssm | 7 | 48 | 14.6% | cbioportal |
| 22 | H1-2 | Ssm | 7 | 48 | 14.6% | cbioportal |
| 20 | DMBT1 | Ssm | 7 | 48 | 14.6% | cbioportal |
| 34 | ZNF814 | Ssm | 7 | 48 | 14.6% | cbioportal |
| 18 | ATM | Ssm | 7 | 48 | 14.6% | cbioportal |
Data updated 22 days agoSource updated 2026-01-07