Subtype
Head and Neck Squamous Cell Carcinoma
CI-CAN-00002836HNSCC · SCCHNExplore in graph →
592 active trials6 approved drugs53 evidence items
- NCIt
- C34447
- OncoTree
- HNSC
- DOID
- 5520
- UMLS CUI
- C1168401
- MeSH
- D000077195
- Other
- 1 more code
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Subtype
CI-CAN-00002836HNSCC · SCCHNExplore in graph →
Clinical trials
1,589 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (247)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05935995 | Intraoperative Assessment of Surgical Margins Using Confocal Microscopy in Comparison With Reference Extemporaneous Examination(HISTOBLOC) | completed | N/A | 42 | Institut de Cancérologie de LorraineOTHER | 1 | Sep 1, 2026 | clinicaltrials |
| NCT04670445 | Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer(UPLIFT) | completed | N/A | 199 | Massachusetts General HospitalOTHER |
| 1 |
| Aug 25, 2026 |
| clinicaltrials |
| NCT05119036 | Adjuvant Treatment Deintensification After Transoral Surgery for Human Papillomavirus-Positive Squamous Cell Carcinoma | completed | N/A | 82 | Indiana UniversityOTHER | 1 | Aug 11, 2026 | clinicaltrials |
| NCT07682285 | Taiwanese Green Propolis for Lipid Profiles, Fatigue, and Quality of Life in Oral Cavity Cancer Survivors(TGP-OCS) | completed | N/A | 25 | Taipei Medical UniversityOTHER | 1 | Jul 2, 2026 | clinicaltrials |
| NCT01772706 | Laser Mucite ORL : Effectiveness of Laser Therapy for Mucositis Induced by a Radio-chemotherapy in Head and Neck Cancer(LaserMucite) | completed | N/A | 97 | Institut Cancerologie de l'OuestOTHER | 1 | Jul 1, 2026 | clinicaltrials |
| NCT04603248 | A Study for Identification of Immune Determinants for Response to Nivolumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma | completed | N/A | 50 | Yonsei UniversityOTHER | 1 | Jun 10, 2026 | clinicaltrials |
| NCT03838601 | Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma 2(ROMA LA-OPSCC2) | completed | N/A | 30 | University Health Network, TorontoOTHER | 1 | Jun 8, 2026 | clinicaltrials |
| NCT04733495 | Group-Mediated Cognitive Behavioral Resistance Exercise Intervention in Head and Neck Cancer Patients Undergoing Chemoradiation Treatment | completed | N/A | 20 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT05278039 | Training Swallowing Initiation During Expiration | completed | N/A | 88 | Northwestern UniversityOTHER | 1 | May 14, 2026 | clinicaltrials |
| NCT05120947 | Hypofractionated Adjuvant Radiotherapy for Resected Head and Neck Cancers(HART-HN) | completed | N/A | 18 | Medical College of WisconsinOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT02510859 | Nutrition and Life QUality Patients With Head and Neck Cancers(NUQUE2) | completed | N/A | 117 | University Hospital, CaenOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT04284540 | Hypofractionated Radiotherapy in Elderly Patients With Head & Neck Squamous Cell Carcinoma | completed | N/A | 37 | Icahn School of Medicine at Mount SinaiOTHER | 1 | Feb 3, 2026 | clinicaltrials |
| NCT03896412 | Detection of Circulating Tumor DNA in p16- Locally Advanced Head Neck Squamous Cell Carcinoma(PERSO-NECK) | completed | N/A | 40 | Centre Henri BecquerelOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT04725396 | Study Comparing Fibula Free-flap MR With or Without PVP in Patients With OOPC(CURVE) | completed | N/A | 132 | UNICANCEROTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT04694846 | Effectiveness of an Enhanced Tobacco Intervention Protocol Compared to Standard Treatment in Helping Head and Neck and Lung Cancer Patients Starting Treatment to Reduce Cigarette Use | completed | N/A | 19 | Thomas Jefferson UniversityOTHER | 1 | Sep 9, 2025 | clinicaltrials |
| NCT03552965 | Margin-Based Vs. Robust Photon Radiotherapy Planning in IMRT of HN-SQCC | completed | N/A | 23 | University of ArkansasOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT06112535 | Prospective Clinical Study to Assess the Safety and Efficacy of Versius, in Transoral Robotic Surgery | completed | N/A | 60 | CMR Surgical LtdINDUSTRY | 1 | Jun 25, 2025 | clinicaltrials |
| NCT04871490 | Improving Detection and Early Action for HPV-positive Oropharynx Cancer(IDEA-HPV) | completed | N/A | 40 | Brigham and Women's HospitalOTHER | 1 | Feb 5, 2025 | clinicaltrials |
| NCT04030130 | Navigation vs Usual Care for Timely Adjuvant Therapy for Patients With Locally Advanced HNSCC(NDURE2) | completed | N/A | 176 | Medical University of South CarolinaOTHER | 1 | Jan 29, 2025 | clinicaltrials |
| NCT05950737 | Sentinel Node Biopsy in Early Oral Cancers a Tertiary Cancer Centre Experience | completed | N/A | 115 | Tata Memorial HospitalOTHER_GOV | 1 | Oct 30, 2024 | clinicaltrials |
| NCT06314711 | Ex Vivo 3D-ultrasound for Oropharyngeal Cancer | completed | N/A | 15 | Rigshospitalet, DenmarkOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT03575949 | Standard and Delayed FDG PET/CT After Chemoradiation Therapy in Assessing Patients With Metastatic Head and Neck Squamous Cell Cancer | completed | N/A | 14 | M.D. Anderson Cancer CenterOTHER | 1 | May 14, 2024 | clinicaltrials |
| NCT02072148 | The Sinai Robotic Surgery Trial in HPV Positive Oropharyngeal Squamous Cell Carcinoma (SCCA) (SIRS TRIAL) | completed | N/A | 112 | Icahn School of Medicine at Mount SinaiOTHER | 1 | May 6, 2024 | clinicaltrials |
| NCT03650699 | Biofeedback Rehabilitation to Improve Speaking and Eating in Public(Biofeedback) | completed | N/A | 34 | University Health Network, TorontoOTHER | 1 | Mar 20, 2024 | clinicaltrials |
| NCT05792228 | A Standardized Intervention to Improve the Management of Chemotherapy-induced Nausea and Vomiting | completed | N/A | 92 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Nov 14, 2023 | clinicaltrials |
| NCT02999646 | Personalized and Cell-based Antitumor Immunization MVX-ONCO-1 in Advanced HNSCC | completed | N/A | 16 | Maxivax SAINDUSTRY | 1 | Sep 28, 2023 | clinicaltrials |
| NCT03281499 | Transoral Robotic Surgery and Tailored Radiotherapy in Unknown Primary and Small Squamous Cell Head and Neck Cancer(FIND) | completed | N/A | 22 | University Health Network, TorontoOTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT03268993 | Effects of Avmacol® in the Oral Mucosa of Patients Following Curative Treatment for Tobacco-related Head and Neck Cancer | completed | N/A | 6 | University of PittsburghOTHER | 1 | Apr 7, 2023 | clinicaltrials |
| NCT04614896 | Use of Ultrasound for Measuring Size of Oral Tongue Cancers | completed | N/A | 30 | Rigshospitalet, DenmarkOTHER | 1 | Mar 30, 2023 | clinicaltrials |
| NCT03518671 | Building a Renewed ImaGe After Head & Neck Cancer Treatment(BRIGHT) | completed | N/A | 11 | Medical University of South CarolinaOTHER | 1 | Mar 8, 2023 | clinicaltrials |
| NCT03032250 | Prepare to Care, A Supported Self-Management Intervention for Head and Neck Cancer CaregiversHead and Neck Cancer | completed | N/A | 35 | Wake Forest University Health SciencesOTHER | 1 | Jan 9, 2023 | clinicaltrials |
| NCT02022098 | Debio 1143-201 Dose-finding and Efficacy Phase I/II Trial | completed | N/A | 144 | Debiopharm International SAINDUSTRY | 2 | Jun 23, 2022 | clinicaltrials |
| NCT00765791 | 2B or Not 2B? Shoulder Function After Level 2B Neck Dissection: A Randomized Controlled Study(2BN2B) | completed | N/A | 40 | University of AlbertaOTHER | 1 | Jun 9, 2022 | clinicaltrials |
| NCT01636544 | Infectious Aetiology of Potentially Malignant Disorders and Squamous Cell Carcinomas of the Oral Cavity(INECOC) | completed | N/A | 100 | Institut PasteurINDUSTRY | 1 | Apr 26, 2022 | clinicaltrials |
| NCT04059861 | Ultrasound in Tongue Cancer- a Help to Decide Depth of Invasion and to Improve the Surgical Margin | completed | N/A | 42 | Region Örebro CountyOTHER | 1 | Dec 27, 2021 | clinicaltrials |
| NCT03510390 | Metformin in Head and Neck Squamous Cell Carcinoma: Effect on Tissue Oxygenation(HEAD-MET) | completed | N/A | 17 | Insel Gruppe AG, University Hospital BernOTHER | 1 | Nov 18, 2021 | clinicaltrials |
| NCT04253808 | Feasibility of a Carbohydrate-restricted, High-fat Diet on Head and Neck Squamous Cell Carcinoma Outcomes(CRHF) | completed | N/A | 39 | University of Illinois at Urbana-ChampaignOTHER | 1 | Nov 5, 2021 | clinicaltrials |
| NCT03212157 | GlucoCEST MRI in Oncology | completed | N/A | 15 | University College, LondonOTHER | 1 | Sep 29, 2021 | clinicaltrials |
| NCT03421912 | Satisfaction and Quality of Life Comparison Between Patients Using Cicaplast Baume B5 Versus Dexeryl for the Management of Cutaneous Toxicities Induced by Epidermal Growth Factor Receptor Inhibitors (iEGFR)(CICAFIX) | completed | N/A | 102 | Centre Leon BerardOTHER | 1 | Jul 9, 2021 | clinicaltrials |
| NCT04098458 | Navigation for Timely Adjuvant Therapy for Patients With Locally Advanced HNSCC | completed | N/A | 18 | Medical University of South CarolinaOTHER | 1 | Mar 22, 2021 | clinicaltrials |
| NCT01663259 | Reduced-intensity Therapy for Oropharyngeal Cancer in Non-smoking HPV-16 Positive Patients | completed | N/A | 43 | University of Michigan Rogel Cancer CenterOTHER | 1 | Jan 19, 2021 | clinicaltrials |
| NCT02025062 | Comprehensive Geriatric Assessment and Head and Neck Elderly Cancer Patients(EGéSOR) | completed | N/A | 499 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Nov 23, 2020 | clinicaltrials |
| NCT01314755 | A Trial of Perioperative Immune Enhancing Feed in Patients Undergoing Surgery for Head and Neck Cancer(IMPACTHN) | completed | N/A | 76 | Terrence JonesOTHER_GOV | 1 | Aug 7, 2020 | clinicaltrials |
| NCT01504932 | Freeze-Dried Black Raspberries in Preventing Oral Cancer Recurrence in High At-Risk Appalachian Patients Oral Cancer Survivors | completed | N/A | 42 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Feb 20, 2020 | clinicaltrials |
| NCT01816841 | Direct Visual Fluorescence in Finding Oral Cancer in High-Risk Patients and Patients Undergoing Routine Dental Care | completed | N/A | 68 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Jan 30, 2020 | clinicaltrials |
| NCT03340038 | Use of a Non-ICU Specialty Ward For Immediate Post-operative Management of Head and Neck Free Flaps(ICU) | completed | N/A | 112 | University of California, DavisOTHER | 1 | Oct 29, 2019 | clinicaltrials |
| NCT03226613 | New Modalities for Detection of Oropharyngeal Cancer | completed | N/A | 51 | Vanderbilt University Medical CenterOTHER | 1 | Mar 13, 2019 | clinicaltrials |
| NCT02035735 | Interest of Narrow Band Imaging in Detection of Upper Aerodigestive Cancers | completed | N/A | 93 | University Hospital, ToulouseOTHER | 1 | Dec 11, 2018 | clinicaltrials |
| NCT01748942 | Dexamethasone in Reducing Oral Pain and Dry Mouth After Surgery in Patients With Oropharyngeal Cancer | completed | N/A | 76 | OHSU Knight Cancer InstituteOTHER | 1 | Jun 19, 2018 | clinicaltrials |
Data updated 22 days agoSource updated Sep 1, 2026source: clinicaltrials