Subtype
Head and Neck Squamous Cell Carcinoma
CI-CAN-00002836HNSCC · SCCHNExplore in graph →
591 active trials6 approved drugs53 evidence items
- NCIt
- C34447
- OncoTree
- HNSC
- DOID
- 5520
- UMLS CUI
- C1168401
- MeSH
- D000077195
- Other
- 1 more code
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Subtype
CI-CAN-00002836HNSCC · SCCHNExplore in graph →
Clinical trials
1,588 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (247)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00031681 | 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) | completed | Phase 1 | 41 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT00049166 | Erlotinib and Radiation Therapy With or Without Cisplatin in Treating Patients With Mouth or Throat Cancer | completed | Phase 1 | 48 | National Cancer Institute (NCI)NIH | 1 |
| Sep 30, 2013 |
| clinicaltrials |
| NCT01927354 | Study on the Interplay Between Twist1 and Other EMT Regulators Through microRNA-29 Family. | unknown | — | 100 | National Taiwan University HospitalOTHER | 1 | Sep 16, 2013 | clinicaltrials |
| NCT00824343 | A Phase II Clinical Trial to Study the Efficacy and Safety of a New Drug P276-00 in Treatment of Recurrent and/or Locally Advanced Head and Neck Cancer(MONARCH) | completed | Phase 2 | 86 | Piramal Enterprises LimitedINDUSTRY | 1 | Jul 10, 2013 | clinicaltrials |
| NCT00459043 | Docetaxel in Combination With Zactima (ZD6474) in Patients With Locally Advanced Squamous Cell Carcinoma of the the Head and Neck | completed | Phase 2 | 30 | Dana-Farber Cancer InstituteOTHER | 1 | Jul 3, 2013 | clinicaltrials |
| NCT00906360 | Sunitinib, Cetuximab, and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck | terminated | Phase 1 | 36 | National Cancer Institute (NCI)NIH | 1 | Jul 2, 2013 | clinicaltrials |
| NCT01830556 | Randomised Phase II, Cetuximab in Combination With 5FU and Cisplatin or Carboplatin Versus Cetuximab in Combination With Paclitaxel and Carboplatin for Treatment of Patients With Metastatic Squamous Cell Carcinoma of the Head and Neck(CETMET) | unknown | Phase 2 | 120 | Karolinska University HospitalOTHER | 2 | May 21, 2013 | clinicaltrials |
| NCT01155609 | L-lysine in Treating Oral Mucositis in Patients Undergoing Radiation Therapy With or Without Chemotherapy For Head and Neck Cancer | completed | N/A | 10 | University of WashingtonOTHER | 1 | May 17, 2013 | clinicaltrials |
| NCT01674374 | Botanical Therapy in Treating Mucositis in Patients With Head and Neck Cancer Who Have Undergone Chemoradiation Therapy | withdrawn | Phase 2 | 0 | Roswell Park Cancer InstituteOTHER | 0 | May 15, 2013 | clinicaltrials |
| NCT00410826 | Cisplatin and Radiation Therapy With or Without Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Head and Neck Cancer | completed | Phase 2 | 204 | University of WashingtonOTHER | 1 | May 10, 2013 | clinicaltrials |
| NCT00089362 | Alvespimycin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors | completed | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Apr 10, 2013 | clinicaltrials |
| NCT01333696 | Pemetrexed as Salvage Treatment in Squamous Cell Carcinoma of Head and Neck | unknown | Phase 2 | 32 | Fudan UniversityOTHER | 1 | Mar 5, 2013 | clinicaltrials |
| NCT00004074 | Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu | completed | Phase 1 | 15 | National Cancer Institute (NCI)NIH | 1 | Feb 28, 2013 | clinicaltrials |
| NCT00096512 | S0420, Sorafenib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer | completed | Phase 2 | 40 | National Cancer Institute (NCI)NIH | 1 | Feb 28, 2013 | clinicaltrials |
| NCT00033618 | Ixabepilone in Treating Patients With Metastatic or Recurrent Squamous Cell Cancer of the Head and Neck | completed | Phase 2 | 144 | National Cancer Institute (NCI)NIH | 1 | Feb 27, 2013 | clinicaltrials |
| NCT00023959 | Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer | completed | Phase 1 | 39 | National Cancer Institute (NCI)NIH | 1 | Feb 7, 2013 | clinicaltrials |
| NCT01783158 | Chromoendoscopy to Detect Early Synchronous Second Primary Esophageal Carcinoma(HNSCC) | completed | — | 132 | University Hospital OstravaOTHER | 1 | Feb 4, 2013 | clinicaltrials |
| NCT00033449 | Gefitinib and Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III or Stage IV Head and Neck Cancer | terminated | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Jan 25, 2013 | clinicaltrials |
| NCT00081211 | Intratumoral PV701 in Treating Patients With Advanced or Recurrent Unresectable Squamous Cell Carcinoma of the Head and Neck | terminated | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Jan 24, 2013 | clinicaltrials |
| NCT00030498 | Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction | completed | Phase 1 | 75 | National Cancer Institute (NCI)NIH | 1 | Jan 16, 2013 | clinicaltrials |
| NCT00068497 | Gefitinib in Treating Patients With Metastatic or Unresectable Head and Neck Cancer or Non-Small Cell Lung Cancer | completed | N/A | 40 | National Cancer Institute (NCI)NIH | 1 | Jan 14, 2013 | clinicaltrials |
| NCT00063895 | Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer, Ovarian Cancer, or Squamous Cell Carcinoma of the Head and Neck | completed | Phase 1 / Phase 2 | 80 | National Cancer Institute (NCI)NIH | 1 | Jan 9, 2013 | clinicaltrials |
| NCT01015664 | Combination of Cisplatin, Cetuximab and Temsirolimus in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck | terminated | Phase 1 / Phase 2 | 11 | University of Tennessee Cancer InstituteOTHER | 1 | Dec 17, 2012 | clinicaltrials |
| NCT01415986 | Interstitial Photodynamic Therapy (PDT) With Temoporfin for Advanced Head and Neck Cancers | terminated | Phase 2 | 1 | University of ArkansasOTHER | 1 | Dec 3, 2012 | clinicaltrials |
| NCT00899054 | Safety and Efficacy Study of P276-00 in Combination With Radiation in Subjects With Advanced Head and Neck Cancer(SPARK) | completed | Phase 1 / Phase 2 | 23 | Piramal Enterprises LimitedINDUSTRY | 1 | Nov 22, 2012 | clinicaltrials |
| NCT01280318 | Profile of Plasma Growth Factors Before and After Head and Neck Oncological or Non-oncological Surgery(HNSCC) | completed | Phase 1 / Phase 2 | 60 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | Nov 14, 2012 | clinicaltrials |
| NCT00038038 | Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole | withdrawn | N/A | 0 | M.D. Anderson Cancer CenterOTHER | 1 | Aug 1, 2012 | clinicaltrials |
| NCT01637194 | Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck Cancer | completed | Phase 1 | 12 | Fox Chase Cancer CenterOTHER | 1 | Jul 11, 2012 | clinicaltrials |
| NCT01321892 | Ex Vivo Multimodal Imaging of Upper Aerodigestive Epithelium | completed | — | 64 | Icahn School of Medicine at Mount SinaiOTHER | 1 | Jun 21, 2012 | clinicaltrials |
| NCT00805012 | Docetaxel and S-1 in Head and Neck Squamous Cell Carcinoma (HNSCC) | terminated | Phase 2 | 96 | Seoul National University HospitalOTHER | 1 | Jul 26, 2011 | clinicaltrials |
| NCT00634777 | Assessment of Regional Response With PET-FDG in Advanced Head and Neck Squamous Cell Carcinoma(pet) | unknown | N/A | 239 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | Jul 20, 2011 | clinicaltrials |
| NCT01377298 | Pazopanib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma | unknown | Phase 2 | 45 | National Taiwan University HospitalOTHER | 1 | Jun 21, 2011 | clinicaltrials |
| NCT01077869 | A Feasibility Study on the Use of F-18-FDG-PET and Optical Imaging in Evaluation of Radiation-induced Oral Mucositis | terminated | — | 10 | University Hospital, GhentOTHER | 1 | May 26, 2011 | clinicaltrials |
| NCT00206219 | Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX) | completed | Phase 3 | 477 | AstraZenecaINDUSTRY | 25 | Jan 27, 2011 | clinicaltrials |
| NCT00371566 | A Study Of Lapatinib Versus Placebo Followed By Chemoradiation In Patients With Locally Advanced Head And Neck Cancer | completed | Phase 2 | 107 | GlaxoSmithKlineINDUSTRY | 5 | Apr 6, 2010 | clinicaltrials |
| NCT00139269 | Study of Docetaxel in Combination With Cisplatin and 5-Fluorouracil in Locally Advanced Squamous Cell Carcinoma of the Head and Neck | completed | Phase 1 / Phase 2 | 38 | Dana-Farber Cancer InstituteOTHER | 0 | Jun 4, 2008 | clinicaltrials |
| NCT00139230 | Combination Chemotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck | completed | Phase 2 | 30 | Dana-Farber Cancer InstituteOTHER | 1 | Jun 3, 2008 | clinicaltrials |
| NCT00652613 | Study of 3-Dimensional Conformal Radiotherapy (3D-CRT) Versus Intensity Modulated Radiotherapy (IMRT) for Head and Neck Squamous Cell Carcinoma (HNSCC) | unknown | Phase 2 | 60 | Tata Memorial HospitalOTHER_GOV | 1 | Apr 11, 2008 | clinicaltrials |
Data updated 22 days agoSource updated Sep 30, 2013source: clinicaltrials