Subtype
Head and Neck Squamous Cell Carcinoma
CI-CAN-00002836HNSCC · SCCHNExplore in graph →
591 active trials6 approved drugs53 evidence items
- NCIt
- C34447
- OncoTree
- HNSC
- DOID
- 5520
- UMLS CUI
- C1168401
- MeSH
- D000077195
- Other
- 1 more code
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Subtype
CI-CAN-00002836HNSCC · SCCHNExplore in graph →
Clinical trials
1,588 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (247)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01949740 | Patient Preferences in Making Treatment Decisions in Patients With Stage I-IVA Oropharyngeal Cancer | terminated | — | 37 | University of ChicagoOTHER | 1 | Sep 2, 2015 | clinicaltrials |
| NCT01192204 | Clinical Evaluation of Bioadhesive Gels for Oral Cancer Chemoprevention | completed | Phase 1 / Phase 2 | 41 | Ohio State UniversityOTHER | 1 | Aug 14, 2015 | clinicaltrials |
| NCT02510872 |
| completed |
| N/A |
| 19 |
| University Hospital, CaenOTHER |
| 1 |
| Jul 29, 2015 |
| clinicaltrials |
| NCT01484847 | A Study of PF-00299804 When Given Through a Feeding Tube in Locally Advanced Head and Neck Squamous Cell Carcinoma | completed | N/A | 6 | University Health Network, TorontoOTHER | 1 | Jul 10, 2015 | clinicaltrials |
| NCT01012258 | Cetuximab With Radiotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck in Chinese Subjects(CHANCE) | completed | Phase 3 | 70 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 1 | Jul 9, 2015 | clinicaltrials |
| NCT00508664 | Docetaxel, Cisplatin (TP) + Radiation +/- Cetuximab in Larynx Carcinoma (CA)(DeLOS II) | completed | Phase 2 | 180 | ClinAssessOTHER | 2 | Jun 2, 2015 | clinicaltrials |
| NCT01794481 | Benefits of Exercise Training in Head and Neck Cancer Patients Undergoing Organ-Preserving Definitive Therapy | completed | N/A | 24 | University of Michigan Rogel Cancer CenterOTHER | 1 | May 20, 2015 | clinicaltrials |
| NCT00458978 | Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer | completed | Phase 2 | 6 | National Cancer Institute (NCI)NIH | 1 | May 5, 2015 | clinicaltrials |
| NCT02126189 | The Princess Alexandra Hospital and the QIMR Berghofer Medical Research Institute Head and Neck Cancer Study | unknown | — | 600 | Queensland Centre of Excellence for Head and Neck CancerOTHER | 1 | Apr 22, 2015 | clinicaltrials |
| NCT02156180 | Identification of Breath Biomarkers in Head and Neck Squamous Cell Carcinoma | suspended | — | 13 | Queensland Centre of Excellence for Head and Neck CancerOTHER | 1 | Apr 22, 2015 | clinicaltrials |
| NCT00114283 | Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer | completed | Phase 2 | 30 | National Cancer Institute (NCI)NIH | 1 | Apr 15, 2015 | clinicaltrials |
| NCT01334320 | Survival Benefit of Elective Neck Dissection in T1,2N0M0 Oral Squamous Cell Carcinoma | unknown | N/A | 448 | Sun Yat-sen UniversityOTHER | 1 | Apr 10, 2015 | clinicaltrials |
| NCT00206752 | Study of Unilateral Neck Irradiation in Patients With SCC of the Head and Neck(Unilateral) | completed | N/A | 45 | Beth Israel Medical CenterOTHER | 1 | Mar 30, 2015 | clinicaltrials |
| NCT01953952 | Radiation Therapy and Cisplatin With or Without Surgery in Treating Patients With Stage III-IV Oropharyngeal Cancer | withdrawn | Phase 2 | 0 | Radiation Therapy Oncology GroupNETWORK | 1 | Mar 20, 2015 | clinicaltrials |
| NCT01133262 | Effectiveness in Head and Neck Cancer Detection Using Positron Emission Tomography (PET) Insert Device | withdrawn | — | 0 | Washington University School of MedicineOTHER | 1 | Mar 10, 2015 | clinicaltrials |
| NCT01334177 | TLR8 Agonist VTX-2337 and Cetuximab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Squamous Cell Cancer of Head and Neck | completed | Phase 1 | 13 | University of WashingtonOTHER | 1 | Mar 5, 2015 | clinicaltrials |
| NCT01379339 | Cabazitaxel - PF Induction Chemotherapy | completed | Phase 1 | 40 | Krzysztof MisiukiewiczOTHER | 1 | Feb 11, 2015 | clinicaltrials |
| NCT02352792 | Hypoxia-based Dose Escalation With Radiochemotherapy in Head and Neck Cancer | unknown | N/A | 90 | University Hospital TuebingenOTHER | 1 | Feb 2, 2015 | clinicaltrials |
| NCT01086826 | Treatment of Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck(H&N07) | completed | Phase 3 | 320 | Associazione Volontari Pazienti OncologiciOTHER | 1 | Jan 26, 2015 | clinicaltrials |
| NCT02017834 | Does the Harmonic Scalpel Reduce Blood Loss and OR Time in Major Head and Neck Cancer Surgery Undergoing Major Surgery for Oral Cavity Squamous Cell Carcinoma?(HS2) | completed | N/A | 36 | University of CalgaryOTHER | 1 | Dec 3, 2014 | clinicaltrials |
| NCT02119559 | Circulating Tumor Cells as an Early Predictive head-and -Neck Squamous-cell Carcinoma(CIRCUTEC) | unknown | N/A | 115 | University Hospital, MontpellierOTHER | 1 | Dec 3, 2014 | clinicaltrials |
| NCT01254734 | Transoral Robotic Surgery in Treating Patients With Benign or Stage I-IV Head and Neck Cancer | terminated | N/A | 7 | City of Hope Medical CenterOTHER | 1 | Nov 10, 2014 | clinicaltrials |
| NCT00507767 | Dasatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer | completed | Phase 2 | 15 | National Cancer Institute (NCI)NIH | 1 | Oct 1, 2014 | clinicaltrials |
| NCT01177956 | A Trial to Determine the Safety and Anti-tumor Activity Profile of the Combination of Cetuximab and Concomitant Cisplatin Plus 5-Fluorouracil (5-FU) in Subjects With Recurrent and/or Metastatic Squamous Cell Carcinoma in Head and Neck(CHANGE) | completed | Phase 3 | 73 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 2 | Sep 3, 2014 | clinicaltrials |
| NCT01718223 | Photodynamic Therapy Using Temoporfin Before Surgery in Treating Patients With Recurrent Oral Cavity or Oropharyngeal Cancer | withdrawn | N/A | 0 | Roswell Park Cancer InstituteOTHER | 0 | Sep 3, 2014 | clinicaltrials |
| NCT01305772 | Identification of Gene Expression Signature for Panitumumab Sensitivity in Untreated Locally Advanced SCCHN(TOP0901) | terminated | Phase 2 | 6 | Neal ReadyOTHER | 1 | Aug 29, 2014 | clinicaltrials |
| NCT01682031 | Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy | terminated | Phase 2 | 18 | Roswell Park Cancer InstituteOTHER | 2 | Aug 22, 2014 | clinicaltrials |
| NCT00911326 | Evaluation of Sentinel Lymph Nodes in Head and Neck Squamous Cell Carcinoma | terminated | Phase 3 | 101 | Navidea BiopharmaceuticalsINDUSTRY | 1 | Aug 8, 2014 | clinicaltrials |
| NCT00387335 | Sunitinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer | completed | Phase 2 | 22 | National Cancer Institute (NCI)NIH | 1 | Jul 25, 2014 | clinicaltrials |
| NCT00002774 | Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer | completed | Phase 2 | 63 | Stanford UniversityOTHER | 1 | Jun 20, 2014 | clinicaltrials |
| NCT01360827 | EMD 1201081 + 5-FU + Cisplatin + Cetuximab in Subjects With Recurrent / Metastatic Squamous Cell Carcinoma of the Head and Neck | terminated | Phase 1 | 13 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 1 | Jun 17, 2014 | clinicaltrials |
| NCT00101348 | Erlotinib and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney, Colorectal, Head and Neck, Pancreatic, or Non-Small Cell Lung Cancer | completed | Phase 1 / Phase 2 | 66 | National Cancer Institute (NCI)NIH | 1 | Jun 11, 2014 | clinicaltrials |
| NCT00049283 | Erlotinib, Docetaxel, and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer | completed | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Jun 6, 2014 | clinicaltrials |
| NCT01425736 | Nimotuzumab in Combination With TPF(Cisplatin ,Fluorouracil and Docetaxel) for Head and Neck Squamous Cell Carcinoma | completed | Phase 2 | 91 | Wei GuoOTHER | 1 | Jun 3, 2014 | clinicaltrials |
| NCT00103259 | Bortezomib With or Without Irinotecan in Treating Patients With Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck | completed | Phase 2 | 71 | National Cancer Institute (NCI)NIH | 1 | May 23, 2014 | clinicaltrials |
| NCT00492089 | Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer | completed | Phase 2 | 11 | National Cancer Institute (NCI)NIH | 1 | May 9, 2014 | clinicaltrials |
| NCT00513435 | Saracatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer | completed | Phase 2 | 9 | National Cancer Institute (NCI)NIH | 1 | Apr 30, 2014 | clinicaltrials |
| NCT01439724 | Low-level Laser Therapy to Prevent Oral Mucositis in Head and Neck Patients | completed | Phase 3 | 94 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 1 | Apr 11, 2014 | clinicaltrials |
| NCT00971932 | Study of Cetuximab in Combination With Chemotherapy in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN) | completed | Phase 2 | 33 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 1 | Apr 8, 2014 | clinicaltrials |
| NCT00098631 | Lapatinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer | completed | Phase 2 | 88 | National Cancer Institute (NCI)NIH | 1 | Jan 7, 2014 | clinicaltrials |
| NCT01268878 | Hematologic Toxicity Observation of the Docetaxel+ Cisplatin+ Fluorouracil (TPF)Medical Protocol(OTOHTPF) | completed | — | 130 | Groupe Oncologie Radiotherapie Tete et CouOTHER | 1 | Jan 3, 2014 | clinicaltrials |
| NCT02024035 | Protocole Advanced RadioTherapy ORL(ART-ORL) | completed | — | 180 | Centre Leon BerardOTHER | 1 | Dec 31, 2013 | clinicaltrials |
| NCT01728480 | Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Receiving Cisplatin and Radiation Therapy | withdrawn | Phase 1 | 0 | Roswell Park Cancer InstituteOTHER | 0 | Dec 11, 2013 | clinicaltrials |
| NCT02004639 | Trismus Prevention, Diagnosis and Management: Radiotherapy Planning, Early Detection, and Physical Therapy Intervention | unknown | N/A | 60 | Far Eastern Memorial HospitalOTHER | 1 | Dec 9, 2013 | clinicaltrials |
| NCT00055770 | Erlotinib Plus Docetaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Head and Neck Cancer | completed | Phase 1 / Phase 2 | 45 | National Cancer Institute (NCI)NIH | 1 | Nov 25, 2013 | clinicaltrials |
| NCT01987934 | Comparison of Morphometric Assessment Using Methyl Green Pyronin and AgNOR Staining of Oral Squamous Cell Carcinoma(OSCC) | unknown | — | 60 | Academy of Interdisciplinary Dental Education and ResearchOTHER | 1 | Nov 20, 2013 | clinicaltrials |
| NCT00095641 | S0225 Capecitabine in Treating Patients Who Have Undergone Surgery for Locally Recurrent or Persistent Head and Neck Cancer | withdrawn | Phase 2 | 0 | SWOG Cancer Research NetworkNETWORK | 0 | Nov 8, 2013 | clinicaltrials |
| NCT01172769 | Efficacy Study of Temsirolimus to Treat Head and Neck Cancer(TEMHEAD) | completed | Phase 2 | 42 | Hannover Medical SchoolOTHER | 1 | Nov 8, 2013 | clinicaltrials |
| NCT01596868 | GP VS TP in the Treatment of Advanced Nasopharyngeal Carcinoma in Northwest China | completed | Phase 2 | 60 | Air Force Military Medical University, ChinaOTHER | 1 | Oct 30, 2013 | clinicaltrials |
| NCT00620139 | Proximal Molecular Effects of Concurrent Chemoradiotherapy on Head and Neck Squamous Cell Carcinoma | completed | — | 17 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Oct 24, 2013 | clinicaltrials |
Data updated 22 days agoSource updated Sep 2, 2015source: clinicaltrials