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Subtype
CI-CAN-00002836HNSCC · SCCHNExplore in graph →
Clinical trials
1,589 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (247)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05927220 | WORST PATTERN OF INVASION IN ORAL SQUAMOUS CELL CARCINOMA | unknown | — | 81 | Armed Forces Institute of Pathology RawalpindiOTHER_GOV | 1 | Jul 3, 2023 | clinicaltrials |
| NCT05876247 | Articulatory Adaptation Following Oral Cancer Treatment(SPOKE) | unknown | — | 50 | University Medical Center GroningenOTHER | 1 | May 30, 2023 |
| clinicaltrials |
| NCT05861557 | Neoadjuvant Radiotherapy Combined With Toripalimab for Locally Advanced Head and Neck Squamous Cell Carcinoma | unknown | Phase 2 | 23 | Tianjin Medical University General HospitalOTHER | 1 | May 17, 2023 | clinicaltrials |
| NCT05843032 | 3D Ultrasound, Specimen Examination by Surgeon, and MRI in Surgical Margin Assessment | unknown | N/A | 27 | Rigshospitalet, DenmarkOTHER | 1 | May 9, 2023 | clinicaltrials |
| NCT05831917 | MRI - Guided Adaptive RadioTHerapy for Dysphagia in Head and Neck Cancer | unknown | N/A | 41 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Apr 26, 2023 | clinicaltrials |
| NCT05831930 | The Effect of Nitozumab in the Treatment of Head and Neck Squamous Cell Carcinoma | unknown | Early Phase 1 | 62 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Apr 26, 2023 | clinicaltrials |
| NCT05821751 | The Effect of Prebiotic Inulin on Patients Affected by R/M HNSCC Treated With Immune Checkpoint Inhibitors(PRINCESS) | unknown | N/A | 40 | Fondazione del Piemonte per l'OncologiaOTHER | 1 | Apr 20, 2023 | clinicaltrials |
| NCT05122507 | Liquid Biopsy of Head and Neck Cancer Patients in Blood and Saliva(KOHACIN) | unknown | — | 200 | Technical University of MunichOTHER | 1 | Apr 12, 2023 | clinicaltrials |
| NCT05803915 | Neoadjuvant Toripalimab Plus Nimotuzumab in Oral Squamous Cell Carcinoma Prior to Radical Therapy | unknown | Phase 2 | 57 | Peking Union Medical College HospitalOTHER | 1 | Apr 7, 2023 | clinicaltrials |
| NCT05766150 | Oral Microbioma and Oral Malignant Disease | unknown | — | 300 | Academisch Ziekenhuis MaastrichtOTHER | 1 | Mar 13, 2023 | clinicaltrials |
| NCT01590355 | A Phase II Randomized Trial for Early-stage Squamous Cell Carcinoma of the Oropharynx: Radiotherapy vs Trans-oral Robotic Surgery (ORATOR)(ORATOR) | unknown | Phase 2 | 68 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sOTHER | 2 | Mar 8, 2023 | clinicaltrials |
| NCT04929067 | Efficacy and Safety of Immunotherapy Combined With Neoadjuvant Chemotherapy in Patients With Locally Advanced HPV (-) Head and Neck Squamous Cell Carcinoma: a Phase II Clinical Trial | unknown | Phase 2 | 39 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Feb 17, 2023 | clinicaltrials |
| NCT04359199 | QUantitative Assessment of Swallowing After Radiation (QUASAR)(QUASAR) | unknown | — | 42 | Loren Mell, MDOTHER | 1 | Feb 10, 2023 | clinicaltrials |
| NCT05578170 | Efficacy and Safety of Neoadjuvant Pembrolizumab in III-IVA Resectable Oral Squamous Cell Carcinoma(PROBES) | unknown | — | 47 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Feb 3, 2023 | clinicaltrials |
| NCT03775525 | Study Evaluating GZ17-6.02 in Patients With Advanced Solid Tumors or in Combination With Capecitabine in Metastatic Hormone Receptor Positive Breast Cancer(GEN602) | unknown | Phase 1 | 127 | Genzada Pharmaceuticals USA, Inc.INDUSTRY | 1 | Dec 23, 2022 | clinicaltrials |
| NCT01855451 | Weekly Cetuximab/RT Versus Weekly Cisplatin/RT in HPV-Associated Oropharyngeal Squamous Cell Carcinoma(HPVOropharynx) | unknown | Phase 3 | 189 | Trans Tasman Radiation Oncology GroupOTHER | 2 | Nov 18, 2022 | clinicaltrials |
| NCT05143268 | Acupuncture for Dysphagia in Head and Neck Squamous Cell Carcinoma(ACP-HN) | unknown | — | 90 | Lorenzo LiviOTHER | 1 | Nov 10, 2022 | clinicaltrials |
| NCT05611463 | Camrelizumab Plus Docetaxel and Cisplatin in Recurrent or Metastatic Oral Squamous Cell Carcinoma Patients(CHANCE) | unknown | Phase 2 | 25 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityOTHER | 1 | Nov 10, 2022 | clinicaltrials |
| NCT05602792 | A Study of T3011 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumors | unknown | Phase 1 / Phase 2 | 233 | ImmVira Pharma Co. LtdINDUSTRY | 1 | Nov 2, 2022 | clinicaltrials |
| NCT03817307 | Validation of USPIO-enhanced MRI for Detection of Lymph Node Metastases in Head and Neck Carcinoma(USPIO-NECK) | unknown | N/A | 25 | Radboud University Medical CenterOTHER | 1 | Oct 26, 2022 | clinicaltrials |
| NCT04803331 | SPIO-enhanced MRI in Oral Cancer for Sentinel Lymph Node Identification(MAG-NODE) | unknown | N/A | 10 | Radboud University Medical CenterOTHER | 1 | Oct 26, 2022 | clinicaltrials |
| NCT05027204 | A Study of Docetaxel for Injection (Albumin-bound) in Combination With Nivolumab in Patients With Head and Neck (SCCHN) | unknown | Phase 1 / Phase 2 | 94 | CSPC ZhongQi Pharmaceutical Technology Co., Ltd.INDUSTRY | 1 | Oct 13, 2022 | clinicaltrials |
| NCT05024383 | Dissecting the Heterogeneity of Oral Cancer Pain | unknown | N/A | 80 | NYU College of DentistryOTHER | 1 | Sep 28, 2022 | clinicaltrials |
| NCT05476965 | Selected De-escalation Radiotherapy for Postoperative Head and Neck Squamous Cell Carcinoma(iCSDeR) | unknown | Phase 2 | 20 | Hubei Cancer HospitalOTHER | 1 | Jul 27, 2022 | clinicaltrials |
| NCT05351762 | Nimotuzumab Combined With Neoadjuvant Chemotherapy in the Treatment of Resectable LA HNSCC | unknown | Phase 2 | 55 | Xijing HospitalOTHER | 0 | Jul 5, 2022 | clinicaltrials |
| NCT02748707 | Effect of COX-2 and EGFR Suppression on Molecular Markers of Angiogenesis and Proliferation in Squamous Cell Carcinoma of Oral Cavity - Prospective Randomized Study(ERLO-XIB) | unknown | Phase 2 | 64 | Tata Memorial HospitalOTHER_GOV | 1 | Apr 28, 2022 | clinicaltrials |
| NCT04213404 | Ribociclib and Spartalizumab in R/M HNSCC(RISE-HN) | unknown | Phase 1 | 13 | National Taiwan University HospitalOTHER | 1 | Apr 21, 2022 | clinicaltrials |
| NCT05293327 | IMP3 and PCNA Expression in Laryngeal Squamous Cell Carcinoma in Sohag Governorate(IMP3PCNA) | unknown | — | 70 | Sohag UniversityOTHER | 1 | Apr 1, 2022 | clinicaltrials |
| NCT03799744 | Safety,Tolerability,and Efficacy of VCN-01 With Durvalumab in R/M Head and Neck Squamous Cell Carcinoma | unknown | Phase 1 | 20 | Institut Català d'OncologiaOTHER | 1 | Mar 28, 2022 | clinicaltrials |
| NCT05299203 | BH4 in the Prevention and Treatment of Radiation-induced Skin Reactions for Head and Neck Squamous Cell Carcinoma (Including Nasopharyngeal Carcinoma) | unknown | Phase 1 | 18 | West China HospitalOTHER | 0 | Mar 28, 2022 | clinicaltrials |
| NCT05291663 | Effect of Accelerated RTH in Squamous Cell Carcinoma in Head and Neck | unknown | — | 100 | Assiut UniversityOTHER | 0 | Mar 23, 2022 | clinicaltrials |
| NCT05289336 | DAHANCA 27 Transoral Laser Microsurgery for T1a Glottic Cancer(DAHANCA 27) | unknown | Phase 2 | 80 | Danish Head and Neck Cancer GroupNETWORK | 1 | Mar 21, 2022 | clinicaltrials |
| NCT05075122 | Tolerability and Efficacy of UV1 Vaccine in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Planned for First-line Treatment With Pembrolizumab(FOCUS) | unknown | Phase 2 | 75 | Martin-Luther-Universität Halle-WittenbergOTHER | 1 | Mar 9, 2022 | clinicaltrials |
| NCT05267353 | Develop and Test the 'Multi-Faced Continuous Exercise Program' in Operable Head and Neck Cancer Patients | unknown | N/A | 390 | National Taiwan University HospitalOTHER | 0 | Mar 4, 2022 | clinicaltrials |
| NCT05150509 | Association of Salivary Amino Acid Level With OSCC Identified By Liquid Chromatography Mass Spectroscopy(OSCC) | unknown | — | 110 | DR. MALA KHANOTHER_GOV | 1 | Feb 22, 2022 | clinicaltrials |
| NCT04740996 | Study of Pembrolizumab in the First Line Therapy for R/M HNSCC in China | unknown | — | 30 | Shi YuankaiUNKNOWN | 1 | Feb 7, 2022 | clinicaltrials |
| NCT05202275 | The Optimization of Antiemetic Regimen for C-RINV in LA-HNSCCs | unknown | Phase 2 | 43 | Chinese Academy of Medical SciencesOTHER | 1 | Jan 21, 2022 | clinicaltrials |
| NCT05189184 | Study of Camrelizumab in Combination With Apatinib Mesylate Plus Albumin-bound Paclitaxel and Cisplatin as the First Line Treatment of Recurrent or Metastatic, UnresectableHead and Neck Squamous Cell Carcinoma(HNSCC) | unknown | Phase 2 | 30 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 0 | Jan 12, 2022 | clinicaltrials |
| NCT02915432 | The Study to Evaluate Toripalimab (JS001) in Patients With Advanced GC, ESCC, NPC, HNSCC | unknown | Phase 1 / Phase 2 | 401 | Shanghai Junshi Bioscience Co., Ltd.OTHER | 1 | Dec 13, 2021 | clinicaltrials |
| NCT05136768 | Sintilimab Combined With Chemotherapy and SBRT in Limited Metastatic Head and Neck Squamous Cell Carcinoma (LM-HNSCC)(LM-HNSCC) | unknown | Phase 2 | 50 | Jun-Lin Yi, MDUNKNOWN | 1 | Nov 29, 2021 | clinicaltrials |
| NCT05117138 | Safety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors | unknown | Phase 1 / Phase 2 | 39 | Beijing Immunochina Medical Science & Technology Co., Ltd.INDUSTRY | 1 | Nov 11, 2021 | clinicaltrials |
| NCT04367909 | A Study of TC(Docetaxel and Carboplatin) Regimen With or Without Nimotuzumab in Recurrent Metastatic Oral Squamous Cell Carcinoma | unknown | Phase 2 | 68 | Xin-Hua XuOTHER | 1 | Nov 8, 2021 | clinicaltrials |
| NCT04650633 | SHR-1701 in Patients With Recurrent/Metastatic Scchn | unknown | Phase 2 | 130 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Oct 29, 2021 | clinicaltrials |
| NCT03843515 | Neoadjuvant Nivolumab for Oral Cancer Combined With FDG and Anti-PD-L1 PET/CT Imaging for Response Prediction(NeoNivo) | unknown | Phase 1 | 17 | Amsterdam UMC, location VUmcOTHER | 1 | Oct 8, 2021 | clinicaltrials |
| NCT05065086 | Single Modality Trans Oral Robotic Surgery for Primary Oropharyngeal Cancer: Exploring the Impact of Surgical Margins on Local Disease Recurrence(STORM) | unknown | — | 500 | Royal Marsden NHS Foundation TrustOTHER | 1 | Oct 8, 2021 | clinicaltrials |
| NCT03942380 | Cell-free Tumor DNA in Head and Neck Cancer Patients | unknown | N/A | 500 | Christian von BuchwaldOTHER | 1 | Sep 21, 2021 | clinicaltrials |
| NCT05024019 | Nimotuzumab Combined With Radiotherapy in High-risk Patients With HNSCC Not Suitable for Cisplatin After Surgery | unknown | Phase 2 | 95 | Eye & ENT Hospital of Fudan UniversityOTHER | 1 | Aug 27, 2021 | clinicaltrials |
| NCT04992988 | Concurrent Chemoradiotherapy With Toripalimab for Local-regional Recurrent Nasopharyngeal Carcinoma: a Prospective, Single-arm, Phase II Trial | unknown | Phase 2 | 40 | Cancer Hospital of Guangxi Medical UniversityOTHER | 1 | Aug 20, 2021 | clinicaltrials |
Data updated 22 days agoSource updated Jul 3, 2023source: clinicaltrials