Cancer Family
Head and Neck Neoplasm
CI-CAN-00000021Explore in graph →
Non-malignant1,571 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000021Explore in graph →
Clinical trials
6,372 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07635420 | Comparing Intraoperative Indocyanine Green Fluorescence Imaging With Standard Clinical Assessment for Flap Perfusion in Head and Neck Reconstruction (VISION Trial)(VISION) | recruiting | Phase 4 | 244 | Region SkaneOTHER | 1 | Sep 29, 2026 | clinicaltrials |
| NCT07822880 | A Study of Selpercatinib (LY3527723) in Participants With Rearranged During Transfection (RET)-Altered Cancers in India | not yet recruiting | Phase 4 | 30 | Eli Lilly and CompanyINDUSTRY | 1 | Sep 23, 2026 |
| clinicaltrials |
| NCT07633613 | Pharmacokinetic Study of Pembrolizumab and Its Impact on Immunity and the Tumor Microenvironment, Which May Explain the Efficacy of Post-immunotherapy Chemotherapy.(CPI) | not yet recruiting | Phase 4 | 110 | Centre Antoine LacassagneOTHER | 0 | Sep 15, 2026 | clinicaltrials |
| NCT07704658 | Pralsetinib DDI Study in Patients With Advanced or Metastatic Solid Tumors | recruiting | Phase 4 | 12 | Rigel PharmaceuticalsINDUSTRY | 1 | Aug 10, 2026 | clinicaltrials |
| NCT00333099 | INEC Study: Immuno-modulating Enteral Nutrition in Cancer | completed | Phase 4 | 250 | University Hospital, Clermont-FerrandOTHER | 1 | Aug 3, 2026 | clinicaltrials |
| NCT06457503 | A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer(TRANSPARENT) | recruiting | Phase 4 | 100 | Coherus Oncology, Inc.INDUSTRY | 2 | Jul 30, 2026 | clinicaltrials |
| NCT07697287 | Oral Mucositis Management in Patients Receiving Radiation for Head and Neck Cancer: An Evaluation of a Barrier Based Treatment(TOPHAT) | active not recruiting | Phase 4 | 29 | McMaster UniversityOTHER | 1 | Jul 13, 2026 | clinicaltrials |
| NCT04246697 | Multimodal Pain Study in Free Flap Patients | completed | Phase 4 | 30 | University of Kansas Medical CenterOTHER | 1 | Jul 7, 2026 | clinicaltrials |
| NCT07600580 | The Association Between Bilateral Intermediate Cervical Plexus Block During Total Thyroidectomy and Surgical Stress Response | recruiting | Phase 4 | 48 | University Hospital DubravaOTHER | 1 | Jun 16, 2026 | clinicaltrials |
| NCT07405086 | Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study | recruiting | Phase 4 | 160 | OHSU Knight Cancer InstituteOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT06162377 | Methylnatrexone In Resectable Head and Neck Squamous Cell Carcinoma (MINK). A "Window of Opportunity" Pilot Study. | recruiting | Phase 4 | 25 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 10, 2026 | clinicaltrials |
| NCT04265430 | Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors | recruiting | Phase 4 | 425 | M.D. Anderson Cancer CenterOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT03573960 | A Study to Evaluate the Safety and Efficacy of Lenvatinib in Participants With Refractory Differentiated Thyroid Cancer | completed | Phase 4 | 50 | Eisai Pharmaceuticals India Pvt. LtdINDUSTRY | 1 | Mar 6, 2026 | clinicaltrials |
| NCT07354698 | Application of Mitoxantrone Hydrochloride Injection in Transoral Robotic Thyroid Cancer Surgery(MHI) | not yet recruiting | Phase 4 | 114 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT04081701 | 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.(DOMINO-START) | recruiting | Phase 4 | 200 | Weill Medical College of Cornell UniversityOTHER | 1 | Nov 21, 2025 | clinicaltrials |
| NCT07158164 | DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment | recruiting | Phase 4 | 100 | Rutgers, The State University of New JerseyOTHER | 1 | Nov 13, 2025 | clinicaltrials |
| NCT07189897 | Apixaban or Enoxaparin After Head and Neck Cancer Surgery | recruiting | Phase 4 | 76 | Kiranya ArnoldOTHER | 1 | Oct 8, 2025 | clinicaltrials |
| NCT01496313 | To Compare The Effects Of Two Doses Of Vandetanib In Patients With Advanced Medullary Thyroid Cancer | completed | Phase 4 | 81 | SanofiINDUSTRY | 9 | Oct 3, 2025 | clinicaltrials |
| NCT07045935 | Metabolic Outcomes in Patients With Prolactinomas Under Dopamine Agonist Treatment(ProBOLIC) | recruiting | Phase 4 | 60 | University Hospital, Basel, SwitzerlandOTHER | 1 | Sep 23, 2025 | clinicaltrials |
| NCT01896479 | A Study of Two Different Doses of Cabozantinib (XL184) in Progressive, Metastatic Medullary Thyroid Cancer(EXAMINER) | active not recruiting | Phase 4 | 247 | ExelixisINDUSTRY | 14 | Sep 2, 2025 | clinicaltrials |
| NCT05294640 | Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures | completed | Phase 4 | 95 | University of California, San FranciscoOTHER | 1 | Jul 8, 2025 | clinicaltrials |
| NCT07034859 | Cabergoline in the Management of Nonfunctioning Pituitary Adenoma | enrolling by invitation | Phase 4 | 30 | National Taiwan University HospitalOTHER | 1 | Jun 24, 2025 | clinicaltrials |
| NCT04489888 | A Study of Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10) | completed | Phase 4 | 101 | Merck Sharp & Dohme LLCINDUSTRY | 5 | Jun 19, 2025 | clinicaltrials |
| NCT05822817 | Comparison of Postoperative Recovery of Sevoflurane and Propofol After Transsphenoidal Surgery | completed | Phase 4 | 252 | Peking Union Medical College HospitalOTHER | 1 | Jun 8, 2025 | clinicaltrials |
| NCT07010393 | Genotype-Driven Neoadjuvant Therapy for Locally Advanced Thyroid Cancer: A Real-World Cohort Study | not yet recruiting | Phase 4 | 335 | Fujian Medical UniversityOTHER | 1 | Jun 8, 2025 | clinicaltrials |
| NCT06879691 | A Trial of Nimotuzumab and Pinkiller Efficacy and Pain in Advanced Head and Neck Squamous Cell Carcinoma | active not recruiting | Phase 4 | 171 | Biotech Pharmaceutical Co., Ltd.OTHER | 1 | Mar 17, 2025 | clinicaltrials |
| NCT04977271 | Mood Disorders in Head and Neck Cancer Patients | withdrawn | Phase 4 | 0 | University of Alabama at BirminghamOTHER | 0 | Feb 4, 2025 | clinicaltrials |
| NCT06807034 | Impact of the Oral Microbiota on Relapse in HNSCC Patients(MICR-ORL) | active not recruiting | Phase 4 | 100 | Institut Sainte CatherineOTHER | 1 | Feb 4, 2025 | clinicaltrials |
| NCT06697782 | Aprepitant and Ondansetron Monotherapy or Combination for Postoperative Nausea and Vomiting in Thyroid Cancer | completed | Phase 4 | 600 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Jan 22, 2025 | clinicaltrials |
| NCT06679816 | Hydrocortisone in Hormone Replacement Therapy for Large Pituitary Neuroendocrine Tumors | recruiting | Phase 4 | 882 | Beijing Tiantan HospitalOTHER | 1 | Jan 14, 2025 | clinicaltrials |
| NCT06734598 | Efficacy of Botox Injection of the Masticatory Muscles in Head &Neck Cancer Patients with Trismus After Radiotherapy | recruiting | Phase 4 | 120 | National Taiwan University HospitalOTHER | 1 | Dec 16, 2024 | clinicaltrials |
| NCT01794793 | Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies | completed | Phase 4 | 337 | RECORDATI GROUPINDUSTRY | 28 | Oct 1, 2024 | clinicaltrials |
| NCT06521697 | Effects of Minimal-Flow Sevoflurane and Multimodal Analgesia in Head and Neck Cancer Surgery | unknown | Phase 4 | 60 | National Taiwan University HospitalOTHER | 0 | Jul 26, 2024 | clinicaltrials |
| NCT04574947 | Lidocaine And Neuromonitoring in Thyroid Surgery | completed | Phase 4 | 110 | Saint Petersburg State University, RussiaOTHER | 1 | Mar 21, 2024 | clinicaltrials |
| NCT05949424 | OPTI - DOSE: Optimal Dosing of Oral Anticancer Drugs in Older Adults(OPTI-DOSE) | unknown | Phase 4 | 30 | University Medical Center GroningenOTHER | 1 | Nov 29, 2023 | clinicaltrials |
| NCT05830500 | Study of Anlotinib in Patients With Advanced Medullary Thyroid Carcinoma | recruiting | Phase 4 | 360 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Jul 25, 2023 | clinicaltrials |
| NCT02484677 | Pharmacokinetics and Pharmacogenetics-based Adaptive Dosing of 5-fu (5-Fluorouracile) in Head & Neck Cancer Patient Undergoing Docetaxel, Cisplatin, 5-Fluorouracile (=TPF) Therapy(5-FU) | completed | Phase 4 | 12 | Assistance Publique Hopitaux De MarseilleOTHER | 1 | May 26, 2023 | clinicaltrials |
| NCT03691441 | Comparative Effectiveness Trial of Transoral Head and Neck Surgery Followed by Adjuvant Radio(Chemo)Therapy Versus Primary Radiochemotherapy for Oropharyngeal Cancer | unknown | Phase 4 | 280 | Universitätsklinikum Hamburg-EppendorfOTHER | 1 | May 17, 2023 | clinicaltrials |
| NCT05046028 | Individualization of Nutritive Sensory Support Of Radiation Therapy | completed | Phase 4 | 100 | National Medical Research Radiological Centre of the Ministry of Health of RussiaOTHER | 1 | Mar 24, 2023 | clinicaltrials |
| NCT04155008 | Nutrition and Pharmacological Algorithm for Oncology Patients Study | terminated | Phase 4 | 1 | Montefiore Medical CenterOTHER | 1 | Nov 16, 2022 | clinicaltrials |
| NCT05055726 | Benzydamine Oromucosal Solution in Oral Mucositis (BOOM)(BOOM) | completed | Phase 4 | 100 | Aziende Chimiche Riunite Angelini Francesco S.p.AINDUSTRY | 2 | Nov 16, 2022 | clinicaltrials |
| NCT03065218 | 99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients | terminated | Phase 4 | 4 | Medstar Health Research InstituteOTHER | 1 | Jul 26, 2022 | clinicaltrials |
| NCT01553032 | Skin Changes in Head and Neck Cancer During Immuno-(Chemo-) And Radiotherapy With Erbitux® (HICARE)(HICARE) | completed | Phase 4 | 139 | University of Heidelberg Medical CenterOTHER | 1 | May 25, 2022 | clinicaltrials |
| NCT05247476 | Type 2 Deiodinase Gene Polymorphism and the Treatment of Hypothyroidism Caused by Thyroidectomy in Thyroid Cancer Patients. | unknown | Phase 4 | 50 | Zhongshan Hospital Xiamen UniversityOTHER | 1 | Feb 18, 2022 | clinicaltrials |
| NCT02351700 | Analgesia Regimens Following Trans-sphenoidal Surgery for Pituitary Tumors | completed | Phase 4 | 62 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Oct 21, 2021 | clinicaltrials |
| NCT03469310 | Minimizing Narcotic Analgesics After Endocrine Surgery | completed | Phase 4 | 126 | Minerva A Romero ArenasOTHER | 1 | May 11, 2021 | clinicaltrials |
| NCT03607227 | Continous Popliteal Block for Microvascular Free Flap Reconstruction in Ear, Nose and Throat Surgery | completed | Phase 4 | 24 | Region SkaneOTHER | 1 | Apr 8, 2021 | clinicaltrials |
| NCT04766827 | Albumin-bound Paclitaxel Combined With Cisplatin Versus Docetaxel Combined With Cisplatin Induced Chemotherapy in Advanced Head and Neck Squamous Tummor | unknown | Phase 4 | 116 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Feb 23, 2021 | clinicaltrials |
| NCT02946918 | Levothyroxine Replacement With Liquid Gel Capsules vs Tablets Post-thyroidectomy | terminated | Phase 4 | 14 | University of Texas Southwestern Medical CenterOTHER | 1 | Dec 1, 2020 | clinicaltrials |
| NCT02379754 | Gentamicin Treatment Prior to Schwannoma Surgery - Residual Function | withdrawn | Phase 4 | 0 | Lund UniversityOTHER | 1 | Sep 11, 2020 | clinicaltrials |
Data updated 1 hour agoSource updated Sep 29, 2026source: clinicaltrials