Cancer Family
Head and Neck Neoplasm
CI-CAN-00000021Explore in graph →
Non-malignant1,572 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000021Explore in graph →
Clinical trials
6,373 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04555837 | Alisertib and Pembrolizumab for the Treatment of Patients With Rb-deficient Head and Neck Squamous Cell Cancer | completed | Phase 1 / Phase 2 | 24 | M.D. Anderson Cancer CenterOTHER | 1 | May 20, 2025 | clinicaltrials |
| NCT03274414 | A Clinical Trial of Endoscopic Surgery Followed by Chemotherapy and Proton Radiation for the Treatment of Tumors in the Sinus and Nasal Passages | completed | Phase 2 | 3 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 16, 2025 |
| clinicaltrials |
| NCT02245100 | Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung Cancer | completed | — | 130 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT02318771 | Radiation Therapy and MK-3475 for Patients With Recurrent/Metastatic Head and Neck Cancer, Renal Cell Cancer, Melanoma, and Lung Cancer | completed | Phase 1 | 41 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT03618654 | Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma | completed | Early Phase 1 | 38 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT04666428 | Effects of Human Papillomavirus Diagnosis on Relationships of Patients With Head and Neck Cancer | completed | — | 30 | Thomas Jefferson UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT06969768 | Proteogenomics for Follicular Cell-derived Thyroid Cancer: Development of a Classification and Prognosis Prediction Model | completed | — | 275 | Seoul National University HospitalOTHER | 1 | May 14, 2025 | clinicaltrials |
| NCT03524326 | Testing Lenvatinib and Cetuximab in Patients With Advanced Head and Neck Squamous Cell Carcinoma and Cutaneous Squamous Cell Carcinoma | completed | Phase 1 | 24 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 13, 2025 | clinicaltrials |
| NCT03944915 | De-Escalation Therapy for Human Papillomavirus Negative Disease(DEPEND) | completed | Phase 2 | 35 | University of ChicagoOTHER | 1 | May 11, 2025 | clinicaltrials |
| NCT06807697 | Quality of Life Before and After Radiotherapy in Patients With Head and Neck Cancer | completed | — | 22 | University of Turin, ItalyOTHER | 1 | May 11, 2025 | clinicaltrials |
| NCT03212469 | A Trial of Durvalumab and Tremelimumab in Combination With SBRT in Patients With Metastatic Cancer(ABIMMUNE) | completed | Phase 1 / Phase 2 | 54 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | May 8, 2025 | clinicaltrials |
| NCT04278092 | Paclitaxel Plus Cetuximab After First-line Checkpoint Inhibitor Failure | completed | Phase 2 | 57 | Medical University of ViennaOTHER | 1 | May 8, 2025 | clinicaltrials |
| NCT04420689 | Bevonescein to Highlight Nerves in Patients Undergoing Head & Neck Surgery | completed | Phase 1 / Phase 2 | 27 | Alume Biosciences, Inc.INDUSTRY | 1 | May 8, 2025 | clinicaltrials |
| NCT00405405 | Phase I of Biologics and Chemoradiation Therapy for Advanced Head and Neck Cancer | completed | Phase 1 | 13 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 6, 2025 | clinicaltrials |
| NCT03107182 | Chemotherapy and Locoregional Therapy Trial (Surgery or Radiation) for Patients With Head and Neck Cancer(OPTIMA-II) | completed | Phase 2 | 72 | University of ChicagoOTHER | 1 | May 6, 2025 | clinicaltrials |
| NCT03377270 | Clinical Impact of Respiratory-Swallow Training on Refractory Dysphagia in Oropharyngeal Head and Neck Cancer | completed | N/A | 49 | VA Office of Research and DevelopmentFED | 1 | May 6, 2025 | clinicaltrials |
| NCT05346237 | Validation and Cross-cultural Adaptation of Croatian SECEL Questionnaire | completed | — | 50 | Osijek University HospitalOTHER | 1 | May 6, 2025 | clinicaltrials |
| NCT00328458 | EPO906 Plus Radiation Therapy for the Treatment of Cancer Patients | completed | Phase 1 | 39 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT00329589 | A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients | completed | Phase 1 | 54 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT00437372 | Phase IB Study Using Sunitinib Plus Radiation Therapy for Cancer Patients | completed | Phase 1 | 39 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT02055833 | Intensive Nutritional Counseling in Head-neck Cancer Patients Undergoing Radiotherapy | completed | N/A | 159 | Fondazione IRCCS Policlinico San Matteo di PaviaOTHER | 1 | May 1, 2025 | clinicaltrials |
| NCT06791174 | Tumor Microenvironmental Collagen Signature to Predict Thyroid Cancer Superior Mediastinal Lymph Node Metastasis(TC-CS-SMLNM) | completed | — | 181 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Apr 30, 2025 | clinicaltrials |
| NCT02983279 | Caloric Restriction Before Surgery in Treating Patients With Endometrial, Prostate, or Breast Cancer | completed | N/A | 49 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Apr 29, 2025 | clinicaltrials |
| NCT04584866 | Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery(PosESS) | completed | N/A | 54 | University Hospital, Basel, SwitzerlandOTHER | 1 | Apr 29, 2025 | clinicaltrials |
| NCT05741008 | Clincal Study of Reduced Target Radiotherapy in Nasopharyngeal Carcinoma | completed | N/A | 20 | First Affiliated Hospital of Kunming Medical UniversityOTHER | 1 | Apr 27, 2025 | clinicaltrials |
| NCT05714436 | Ii-HANC Improving Incurable Head and Neck Cancer Healthcare Experiences | completed | — | 69 | Sheffield Teaching Hospitals NHS Foundation TrustOTHER | 1 | Apr 25, 2025 | clinicaltrials |
| NCT03342911 | Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery | completed | Phase 2 | 34 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Apr 24, 2025 | clinicaltrials |
| NCT05275946 | Targeted Alpha Therapy Using Astatine (At-211) Against Differentiated Thyroid Cancer | completed | Phase 1 | 11 | Osaka UniversityOTHER | 1 | Apr 24, 2025 | clinicaltrials |
| NCT04752384 | Transdermal Buprenorphine for the Treatment of Radiation-Induced Mucositis Pain in Head and Neck Cancer Patients | completed | Phase 2 | 20 | Medical College of WisconsinOTHER | 1 | Apr 20, 2025 | clinicaltrials |
| NCT06924242 | Thyroid Cancer in Surgical Treated Multinodular Goiter | completed | — | 223 | University of FoggiaOTHER | 1 | Apr 11, 2025 | clinicaltrials |
| NCT03927183 | Extended Support for Persons With Pituitary Tumours After Surgery | completed | N/A | 86 | Göteborg UniversityOTHER | 1 | Apr 6, 2025 | clinicaltrials |
| NCT04925284 | Study of XB002 in Subjects With Solid Tumors (JEWEL-101) | completed | Phase 1 | 269 | ExelixisINDUSTRY | 9 | Apr 4, 2025 | clinicaltrials |
| NCT02249572 | Vestibular Schwannoma - Radiosurgery or Expectation: V-REX.(V-REX) | completed | N/A | 100 | Haukeland University HospitalOTHER | 1 | Apr 2, 2025 | clinicaltrials |
| NCT03894618 | SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas | completed | Phase 1 | 49 | Shattuck Labs, Inc.INDUSTRY | 4 | Apr 2, 2025 | clinicaltrials |
| NCT05410821 | Evaluation of 177Lu-DOTA-EB-FAPI in Patients With Metastatic Radioactive Iodine Refractory Thyroid Cancer | completed | Phase 1 | 12 | The First Affiliated Hospital of Xiamen UniversityOTHER | 1 | Apr 1, 2025 | clinicaltrials |
| NCT05583097 | The Ultracyt Study - is EU-TIRADS Useful in Selecting Nodules for Fine Needle Aspiration Cytology?(Ultracyt) | completed | N/A | 195 | Vastra Gotaland RegionOTHER_GOV | 1 | Apr 1, 2025 | clinicaltrials |
| NCT00381641 | Sunitinib Malate in Treating Patients With Thyroid Cancer That Did Not Respond to Iodine I 131 and Cannot Be Removed by Surgery | completed | Phase 2 | 63 | National Cancer Institute (NCI)NIH | 1 | Mar 28, 2025 | clinicaltrials |
| NCT03754933 | Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck Cancer | completed | Phase 1 / Phase 2 | 10 | GeoVax, Inc.INDUSTRY | 1 | Mar 27, 2025 | clinicaltrials |
| NCT03905005 | Jaw Reconstruction With Printed Titanium and Free Tissue Transfer(JaW PrinT) | completed | — | 20 | University of South WalesOTHER | 1 | Mar 25, 2025 | clinicaltrials |
| NCT04830592 | A Study of NG-641 and Pembrolizumab in Squamous Cell Carcinoma of the Head and Neck(MOAT) | completed | Phase 1 | 36 | Akamis BioINDUSTRY | 1 | Mar 24, 2025 | clinicaltrials |
| NCT03195699 | Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers | completed | Phase 1 | 64 | Tvardi Therapeutics, IncorporatedINDUSTRY | 1 | Mar 21, 2025 | clinicaltrials |
| NCT06457594 | Prospective PROM and PREM Analysis Demonstrating Specification Advantage and Language Barriers | completed | — | 60 | Hadassah Medical OrganizationOTHER | 1 | Mar 19, 2025 | clinicaltrials |
| NCT04173247 | Study of KeraStat Cream for Radiation Dermatitis During Head and Neck Radiotherapy | completed | N/A | 28 | Wake Forest University Health SciencesOTHER | 1 | Mar 17, 2025 | clinicaltrials |
| NCT03662698 | Effect of Guided Imagery for Radiotherapy-Related Distress in Patients With Head and Neck Cancer | completed | N/A | 57 | University of Colorado, DenverOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT03602911 | A Comparison of NETSPOT Imaging Versus F-FDG-PET in Head and Neck Cancer Patients | completed | Phase 2 | 20 | West Virginia UniversityOTHER | 1 | Mar 12, 2025 | clinicaltrials |
| NCT02395367 | Prospective, Observational, Real-world Oral Malignant Tumors Study(POROMS) | completed | — | 30,000 | Beijing Stomatological Hospital, Capital Medical UniversityOTHER | 1 | Mar 7, 2025 | clinicaltrials |
| NCT04736810 | A Study of Penpulimab Combination Therapy in Patients With Advanced Nasopharyngeal Carcinoma | completed | Phase 2 | 28 | AkesoINDUSTRY | 1 | Mar 7, 2025 | clinicaltrials |
| NCT06865313 | Functional Evaluation After Maxillectomy and Scapular Free Flap Reconstruction | completed | — | 16 | Hôpital de la Croix-RousseOTHER | 1 | Mar 7, 2025 | clinicaltrials |
| NCT02289209 | Reirradiation With Pembrolizumab in Locoregional Inoperable Recurrence or Second Primary Squamous Cell CA of the Head and Neck | completed | Phase 2 | 48 | Dan ZandbergOTHER | 1 | Mar 6, 2025 | clinicaltrials |
| NCT05697198 | PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine(PREFER) | completed | — | 1,429 | Labcorp Corporation of America Holdings, IncINDUSTRY | 1 | Mar 6, 2025 | clinicaltrials |
Data updated 23 days agoSource updated May 20, 2025source: clinicaltrials