Cancer Family
Head and Neck Neoplasm
CI-CAN-00000021Explore in graph →
Non-malignant1,571 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000021Explore in graph →
Clinical trials
6,372 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05290194 | Radiotherapy Combined With PD-1 Monoclonal Antibody and Capecitabine in the Treatment of Nasopharyngeal Carcinoma | withdrawn | Phase 2 | 0 | Fifth Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 1 | Sep 23, 2026 | clinicaltrials |
| NCT04040673 | RAman For Thyroid cancER(RAFTER) | withdrawn | — | 0 | Gloucestershire Hospitals NHS Foundation TrustOTHER | 1 | Sep 17, 2026 |
| clinicaltrials |
| NCT05648461 | Phase II Study Exploring Five Fractions of Post-operative Radiation Therapy in Head and Neck Cancer(Accelerate) | withdrawn | N/A | 0 | All India Institute of Medical SciencesOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT06990737 | Phase 2 Pragmatic Trial of Sentinel Lymph Node Biopsy (SLNB) in Patients With Clinically Node-Negative (cN0), High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) of the Head and Neck | withdrawn | Phase 2 | 0 | University of California, DavisOTHER | 0 | Aug 31, 2026 | clinicaltrials |
| NCT06133790 | Profiles of Expression in HPV+ Versus HPV Head and Neck Cancers(HPVNGS) | withdrawn | — | 0 | GCS Ramsay Santé pour l'Enseignement et la RechercheOTHER | 1 | Aug 20, 2026 | clinicaltrials |
| NCT05423197 | 89Zr-Panitumumab for Assessment of Suspected Metastatic Lesions on 18F-FDG-PET/CT in HNSCC | withdrawn | Phase 2 | 0 | Andrei IagaruOTHER | 1 | Aug 17, 2026 | clinicaltrials |
| NCT07614828 | Exploratory Clinical Study of Neoadjuvant Immunotherapy Combined With Chemotherapy in Malignant Melanoma of Nasal and Paranasal Mucosa | withdrawn | Phase 2 | 0 | Eye & ENT Hospital of Fudan UniversityOTHER | 1 | Jul 10, 2026 | clinicaltrials |
| NCT07216833 | Decitabine and Nivolumab in Participants With Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck | withdrawn | Phase 1 | 0 | Case Comprehensive Cancer CenterOTHER | 1 | Jun 22, 2026 | clinicaltrials |
| NCT01451853 | SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss | withdrawn | Phase 2 | 0 | Sound Pharmaceuticals, IncorporatedINDUSTRY | 1 | Jun 3, 2026 | clinicaltrials |
| NCT05363709 | BALSTILIMAB on Viral Clearance in HPV+ Oropharyngeal Cancer Patients | withdrawn | Phase 2 | 0 | M.D. Anderson Cancer CenterOTHER | 0 | May 12, 2026 | clinicaltrials |
| NCT01536782 | Optimal Tube Feeding Method in Head and Neck Cancer Patients | withdrawn | N/A | 0 | Baylor Research InstituteOTHER | 1 | Apr 29, 2026 | clinicaltrials |
| NCT03953352 | Evaluation of the Automatic Deformable Recontouring on the Daily MVCT for Head and Neck Cancer Adaptive Radiotherapy(GIRAFE) | withdrawn | N/A | 0 | Institut Claudius RegaudOTHER | 1 | Apr 15, 2026 | clinicaltrials |
| NCT05296135 | Predicting Immunotherapy Efficacy in Head and Neck Squamous Cell Cancer(PREDAPT-HNSCC2) | withdrawn | — | 0 | Cofactor Genomics, Inc.INDUSTRY | 1 | Feb 27, 2026 | clinicaltrials |
| NCT05850663 | Quality of Life Assessment of Radiotherapy in Recurrent Head and Neck Cancer | withdrawn | N/A | 0 | University of OklahomaOTHER | 0 | Feb 3, 2026 | clinicaltrials |
| NCT06163664 | Role of ChatGPT in Vestibular Schwannoma Management | withdrawn | N/A | 0 | University of Southern CaliforniaOTHER | 0 | Jan 13, 2026 | clinicaltrials |
| NCT03261726 | Maintaining Cochlear Patency After VIIIth Nerve Surgery | withdrawn | N/A | 0 | Henry Ford Health SystemOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT06603155 | Time Restricted Eating (TRE) in Metastatic Head and Neck Squamous Cell Cancer (mHNSCC) or Unresectable or Metastatic Renal Cell Carcinoma (RCC) | withdrawn | N/A | 0 | Duke UniversityOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT05668949 | Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC) | withdrawn | Phase 1 / Phase 2 | 0 | M.D. Anderson Cancer CenterOTHER | 0 | Dec 17, 2025 | clinicaltrials |
| NCT05845307 | Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and Neck | withdrawn | Early Phase 1 | 0 | M.D. Anderson Cancer CenterOTHER | 0 | Dec 8, 2025 | clinicaltrials |
| NCT04741256 | Implementation of a Standardized Tracheostomy Education Discharge Protocol | withdrawn | N/A | 0 | Case Comprehensive Cancer CenterOTHER | 1 | Dec 2, 2025 | clinicaltrials |
| NCT06804850 | Neoadjuvant Radiotherapy Plus Targeted Therapy and Immunotherapy vs. Targeted Therapy Plus Immunotherapy in Resectable HNSCC | withdrawn | Phase 2 | 0 | West China HospitalOTHER | 0 | Nov 19, 2025 | clinicaltrials |
| NCT05954676 | Online Peri-operative Education Program for Patients Undergoing Major Head & Neck Surgery | withdrawn | N/A | 0 | Washington University School of MedicineOTHER | 0 | Oct 28, 2025 | clinicaltrials |
| NCT05774535 | Prospective, Observational Study on the Carotid Intima-media Thickness in Patients Undergoing Thyroid Surgery(TIROVASC) | withdrawn | — | 0 | Istituto Auxologico ItalianoOTHER | 1 | Oct 2, 2025 | clinicaltrials |
| NCT05754216 | Intraoperative Identification and Stimulation of the Glossopharyngeal Nerve | withdrawn | N/A | 0 | Vanderbilt University Medical CenterOTHER | 1 | Oct 1, 2025 | clinicaltrials |
| NCT05108233 | Evaluation of Sleep Quality in Head and Neck Cancer Patients Throughout Treatment Course | withdrawn | — | 0 | Thomas Jefferson UniversityOTHER | 1 | Sep 29, 2025 | clinicaltrials |
| NCT01326468 | Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer | withdrawn | N/A | 0 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 0 | Sep 25, 2025 | clinicaltrials |
| NCT06276946 | Sparing Parotid Ducts Via MRI Sialography for Reduced Patient Reported Xerostomia | withdrawn | N/A | 0 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Sep 5, 2025 | clinicaltrials |
| NCT06362421 | Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer | withdrawn | — | 0 | Wake Forest University Health SciencesOTHER | 0 | Jul 31, 2025 | clinicaltrials |
| NCT06347185 | Simultaneous Care in Recurrent and/or Metastatic Head and Neck Cancer: the SupCare Study(SupCare) | withdrawn | N/A | 0 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 0 | Jul 17, 2025 | clinicaltrials |
| NCT06086925 | A Window of Opportunity Study of Black Raspberry for Patients With HNSCC | withdrawn | Early Phase 1 | 0 | Mitchell MachtayOTHER | 0 | Jul 11, 2025 | clinicaltrials |
| NCT05879484 | Study of Front Line Pembrolizumab and Valemetostat in PD-L1 Positive, HPV-Negative Recurrent/Metastatic Squamous Cell Carcinoma (SCC) of the Head and Neck: The PANTHERAS | withdrawn | Phase 1 / Phase 2 | 0 | National Cancer Institute (NCI)NIH | 1 | Jul 10, 2025 | clinicaltrials |
| NCT06494046 | Defining Musical Toxicity and Its Effect on Patient Well-being | withdrawn | — | 0 | Mayo ClinicOTHER | 1 | Jun 4, 2025 | clinicaltrials |
| NCT04595981 | Chemo-embolization for Head and Neck Cancer | withdrawn | Phase 2 | 0 | University of Alabama at BirminghamOTHER | 1 | Apr 27, 2025 | clinicaltrials |
| NCT04196933 | Analysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma | withdrawn | N/A | 0 | Massachusetts Eye and Ear InfirmaryOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT05608369 | Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCC(HPV) | withdrawn | Phase 2 | 0 | Case Comprehensive Cancer CenterOTHER | 1 | Apr 4, 2025 | clinicaltrials |
| NCT01345084 | Study Comparing Radiation Therapy and Chemotherapy With or Without Nimotuzumab(NICAP) | withdrawn | Phase 3 | 0 | Eurofarma Laboratorios S.A.INDUSTRY | 1 | Mar 28, 2025 | clinicaltrials |
| NCT05452408 | Antitumor-B KAC PK Study | withdrawn | Phase 1 | 0 | Medical College of WisconsinOTHER | 1 | Mar 18, 2025 | clinicaltrials |
| NCT05743270 | Study of RP3 in Combination With Nivolumab and Other Therapy in Patients With Locoregionally Advanced or Recurrent SCCHN | withdrawn | Phase 2 | 0 | Replimune, Inc.INDUSTRY | 8 | Mar 11, 2025 | clinicaltrials |
| NCT06094621 | Effect of Pre-operative Virtual Visits on Patients With Head and Neck Cancer Undergoing Surgery | withdrawn | — | 0 | University of Michigan Rogel Cancer CenterOTHER | 0 | Mar 7, 2025 | clinicaltrials |
| NCT03169764 | QUILT-3.047: NANT Head and Neck Squamous Cell Carcinoma (HNSCC) Vaccine: Combination Immunotherapy in Subjects With HNSCC Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy | withdrawn | Phase 1 / Phase 2 | 0 | ImmunityBio, Inc.INDUSTRY | 0 | Feb 24, 2025 | clinicaltrials |
| NCT06199453 | The Evaluation of the Effectiveness, Safety and Tolerability of Treatment, Using a PSMA-Lu177, in Patients with ACC- an Open, Non-commercial Clinical Trial(LuRM_ACC/2023) | withdrawn | Phase 2 | 0 | Maria Sklodowska-Curie National Research Institute of OncologyOTHER | 1 | Feb 10, 2025 | clinicaltrials |
| NCT04977271 | Mood Disorders in Head and Neck Cancer Patients | withdrawn | Phase 4 | 0 | University of Alabama at BirminghamOTHER | 0 | Feb 4, 2025 | clinicaltrials |
| NCT04272294 | Functional and Molecular Characterization of Treatment Response in Tumors in the Oral Cavity Using Optical Spectroscopy | withdrawn | N/A | 0 | University of ArkansasOTHER | 1 | Nov 26, 2024 | clinicaltrials |
| NCT04985357 | Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs | withdrawn | — | 0 | Travera IncINDUSTRY | 0 | Nov 25, 2024 | clinicaltrials |
| NCT00756795 | Increasing Physical Activity of Patients With Head and Neck Cancer (I-PAP Study)(I-PAP) | withdrawn | N/A | 0 | University of NebraskaOTHER | 0 | Sep 23, 2024 | clinicaltrials |
| NCT05849142 | Feasibility of Adaptive Radiation Therapy for Human-papilloma Virus-positive Oropharyngeal Cancer Patients on MRIdian Linac(OPC-V) | withdrawn | N/A | 0 | University of MiamiOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT03423264 | PROGRESS Trial - Prophylactic Gabapentin for Relief of Symptoms and Improved Swallowing | withdrawn | Phase 2 | 0 | University of ChicagoOTHER | 1 | Jul 31, 2024 | clinicaltrials |
| NCT06084845 | Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer | withdrawn | Phase 2 | 0 | ECOG-ACRIN Cancer Research GroupNETWORK | 0 | Jul 25, 2024 | clinicaltrials |
| NCT06357858 | ASTX727 and Nivolumab in Squamous Cell Carcinoma of the Head and Neck | withdrawn | Phase 1 | 0 | Case Comprehensive Cancer CenterOTHER | 1 | Jul 3, 2024 | clinicaltrials |
| NCT05471401 | GI Organ Tracking Via Balloon Applicators | withdrawn | N/A | 0 | Washington University School of MedicineOTHER | 0 | Jun 13, 2024 | clinicaltrials |
Data updated 5 days agoSource updated Sep 23, 2026source: clinicaltrials