Cancer Family
Genitourinary System Neoplasm
CI-CAN-00000018Explore in graph →
Non-malignant3,846 active trials61 approved drugs306 evidence items
- NCIt
- C156482
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Cancer Family
CI-CAN-00000018Explore in graph →
Genomics
114 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
98 cases with simple somatic mutation data · 98 cases total · 2026-01-07 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | VHL |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 25 |
| 98 |
| 25.5% |
| cbioportal |
| 2 | KDM5C | Ssm | 9 | 98 | 9.2% | cbioportal |
| 5 | SYNE2 | Ssm | 7 | 98 | 7.1% | cbioportal |
| 4 | LRP1B | Ssm | 7 | 98 | 7.1% | cbioportal |
| 3 | BAP1 | Ssm | 7 | 98 | 7.1% | cbioportal |
| 6 | TP53 | Ssm | 6 | 98 | 6.1% | cbioportal |
| 7 | AHNAK | Ssm | 5 | 98 | 5.1% | cbioportal |
| 9 | CSMD3 | Ssm | 5 | 98 | 5.1% | cbioportal |
| 8 | AKAP13 | Ssm | 5 | 98 | 5.1% | cbioportal |
| 11 | SPTBN4 | Ssm | 5 | 98 | 5.1% | cbioportal |
| 10 | RYR1 | Ssm | 5 | 98 | 5.1% | cbioportal |
| 12 | CARD11 | Ssm | 4 | 98 | 4.1% | cbioportal |
| 15 | SETD2 | Ssm | 4 | 98 | 4.1% | cbioportal |
| 16 | ZNF804A | Ssm | 4 | 98 | 4.1% | cbioportal |
| 14 | NAV3 | Ssm | 4 | 98 | 4.1% | cbioportal |
| 13 | FAM111B | Ssm | 4 | 98 | 4.1% | cbioportal |
| 17 | ATRNL1 | Ssm | 3 | 98 | 3.1% | cbioportal |
| 20 | KMT2C | Ssm | 3 | 98 | 3.1% | cbioportal |
| 19 | FMN2 | Ssm | 3 | 98 | 3.1% | cbioportal |
| 24 | SHANK1 | Ssm | 3 | 98 | 3.1% | cbioportal |
| 23 | PZP | Ssm | 3 | 98 | 3.1% | cbioportal |
| 18 | CUL7 | Ssm | 3 | 98 | 3.1% | cbioportal |
| 25 | TSC1 | Ssm | 3 | 98 | 3.1% | cbioportal |
| 21 | LRRK2 | Ssm | 3 | 98 | 3.1% | cbioportal |
| 22 | MTOR | Ssm | 3 | 98 | 3.1% | cbioportal |
| 58 | MUC7 | Ssm | 2 | 98 | 2% | cbioportal |
| 42 | EDRF1 | Ssm | 2 | 98 | 2% | cbioportal |
| 26 | ADCY9 | Ssm | 2 | 98 | 2% | cbioportal |
| 36 | COG4 | Ssm | 2 | 98 | 2% | cbioportal |
| 27 | AFDN | Ssm | 2 | 98 | 2% | cbioportal |
Data updated 22 days agoSource updated 2026-01-07