Subtype
Esophageal and Gastroesophageal Junction Carcinoma
CI-CAN-00002608Explore in graph →
460 active trials11 approved drugs34 evidence items
- NCIt
- C203673
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Subtype
CI-CAN-00002608Explore in graph →
Clinical trials
1,310 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (120)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02564367 | Feasibility Study of Adjuvant Treatment With S-1 in Patients After R0-Resection of Adenocarcinoma of the Stomach and Esophagogastric Junction(S-1 adjuvant) | completed | Phase 1 / Phase 2 | 30 | AIO-Studien-gGmbHOTHER | 1 | Apr 29, 2021 | clinicaltrials |
| NCT04866381 | An Exploratory Clinical Study of SHR6390 and SHR1020 in the Treatment of Esophageal Squamous Cell Carcinoma After Progression on PD-1 Antibody | unknown | Phase 2 | 87 | Tianjin Medical University Cancer Institute and HospitalOTHER |
| 1 |
| Apr 29, 2021 |
| clinicaltrials |
| NCT04442984 | FOLFOX6 Versus mFOLFIRINOX as First Line Chemotherapy in Metastatic Gastric Cancer or Esophagogastric Junction Adenocarcinoma (Type II-III)(IRIGA) | unknown | Phase 2 | 326 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Apr 13, 2021 | clinicaltrials |
| NCT03585530 | Raltitrexed Concurrent With Radiotherapy for Elderly Chinese Patients With Squamous Cell Carcinoma of Esophagus | unknown | Phase 2 | 32 | Huai'an First People's HospitalOTHER | 1 | Apr 6, 2021 | clinicaltrials |
| NCT02128243 | Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer(MATEO) | completed | Phase 2 | 242 | AIO-Studien-gGmbHOTHER | 1 | Mar 26, 2021 | clinicaltrials |
| NCT04818476 | Outcomes of Endoscopically Resected High-risk Mucosal and Low- and High-risk Submucosal Adenocarcinoma Arising in Barrett's Esophagus | unknown | — | 1,000 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 7 | Mar 26, 2021 | clinicaltrials |
| NCT04813406 | Study of Anlotinib Plus Sintilimab in the Treatment of Advanced Esophageal Squamous Cell Carcinoma | unknown | N/A | 53 | Henan Provincial People's HospitalOTHER | 0 | Mar 24, 2021 | clinicaltrials |
| NCT04810663 | Outcome of Radiation Therapy in Operated Gastric Cancer | unknown | — | 40 | Assiut UniversityOTHER | 0 | Mar 23, 2021 | clinicaltrials |
| NCT02272699 | Neoadjuvant Treatment of Nimotuzumab With Chemotherapy or Radiotherapy in Resectable Esophageal Squamous Cell Carcinoma | withdrawn | Phase 2 / Phase 3 | 0 | Peking UniversityOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT02645864 | Apatinib and Irinotecan Combination Treatment in Esophageal Squamous Cell Carcinoma | completed | Phase 1 | 12 | Peking UniversityOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT04797507 | SHR-1210 in Combination With Anlotinib in Patients With Advanced or Metastatic Esophageal Squamous Cell Cancer | unknown | Phase 2 | 33 | Peking Union Medical College HospitalOTHER | 0 | Mar 15, 2021 | clinicaltrials |
| NCT04773769 | Study of Guanábana Leaves for The Treatment of Patients With Gastric, Gastroesophageal Junction, Pancreatic and Colorectal Adenocarcinomas; Hepatocellular Carcinoma, and Low Grade Lymphomas | unknown | N/A | 54 | Auxilio Mutuo Cancer CenterOTHER | 1 | Feb 26, 2021 | clinicaltrials |
| NCT04084158 | A Study of Toripalimab Combined With Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma. | suspended | Phase 2 | 100 | Zhejiang Cancer HospitalOTHER | 1 | Feb 23, 2021 | clinicaltrials |
| NCT04764240 | Precisely Estimation of the Prognostic Value of Lymph Node in ESCC | completed | — | 3,700 | Shanghai Cancer Hospital, ChinaOTHER | 0 | Feb 23, 2021 | clinicaltrials |
| NCT04767295 | A Study of Camrelizumab Combined With Chemotherapy as Neoadjuvant Therapy in Adcanced Esophageal Squamous Cell Carcinoma (ESCC) | unknown | Phase 2 | 28 | Hunan Cancer HospitalOTHER | 1 | Feb 23, 2021 | clinicaltrials |
| NCT04764084 | Niraparib Combined With Anlotinib in Homologous Recombination Repair (HRR) Gene-mutated Advanced Solid Tumors | unknown | Phase 1 | 52 | Peking University Cancer Hospital & InstituteOTHER | 1 | Feb 21, 2021 | clinicaltrials |
| NCT04759235 | Multimodal Functional Imaging Combined With Metabolomics in Predicting the Efficacy of nCRT for Locally Advanced ESCC | unknown | — | 118 | RenJi HospitalOTHER | 1 | Feb 18, 2021 | clinicaltrials |
| NCT00064259 | A Phase I/II Study of Oblimersen Plus Cisplatin and Fluorouracil in Gastric & Esophageal Junction Cancer | terminated | Phase 1 / Phase 2 | 15 | National Cancer Institute (NCI)NIH | 1 | Feb 17, 2021 | clinicaltrials |
| NCT02644408 | Megestrol Acetate for the Improvement of Quality of Life in Esophageal Cancer With Chemoradiotherapy | completed | Phase 3 | 184 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT04741490 | Camrelizumab Combined With Radiotherapy for Adjuvant Treatment of Esophageal Squamous Cell Carcinoma After Surgery | unknown | N/A | 20 | Fuzhou General HospitalOTHER | 1 | Feb 5, 2021 | clinicaltrials |
| NCT04514822 | Quantitative Evaluation of Metastatic Lymph Nodes With Dynamic 18F-FDG PET/CT in Patients With ESCC | unknown | N/A | 40 | Fifth Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 1 | Feb 4, 2021 | clinicaltrials |
| NCT03116152 | Study of IBI308 With Advanced/Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-line Treatment | completed | Phase 2 | 190 | Innovent Biologics (Suzhou) Co. Ltd.INDUSTRY | 1 | Feb 3, 2021 | clinicaltrials |
| NCT00061932 | Bortezomib With or Without Irinotecan in Treating Patients With Cancer of the Gastroesophageal Junction or Stomach | completed | Phase 2 | 41 | National Cancer Institute (NCI)NIH | 1 | Feb 2, 2021 | clinicaltrials |
| NCT04225364 | Efficacy of Neoadjuvant PD-1 Blockade Plus Chemotherapy for Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 56 | Guangzhou Institute of Respiratory DiseaseOTHER | 1 | Feb 2, 2021 | clinicaltrials |
| NCT03083613 | Raltitrexed and Paclitaxel for Gastric or Gastroesophageal Junction Adenocarcinoma | completed | Phase 2 | 41 | Chinese Academy of Medical SciencesOTHER | 1 | Feb 1, 2021 | clinicaltrials |
| NCT02234596 | Nintedanib in Patients With Advanced Esophagogastric Cancer | completed | Phase 2 | 34 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jan 25, 2021 | clinicaltrials |
| NCT01183559 | A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery | completed | Phase 1 | 9 | Fox Chase Cancer CenterOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT02572687 | A Study of Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies | completed | Phase 1 | 85 | Eli Lilly and CompanyINDUSTRY | 8 | Jan 20, 2021 | clinicaltrials |
| NCT01766986 | Staging and Outcome Depending on Surgical Treatment in Adenocarcinomas of the Oesophagogastric Junction | completed | — | 130 | Universitätsklinikum Hamburg-EppendorfOTHER | 0 | Jan 6, 2021 | clinicaltrials |
| NCT01598077 | A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer | completed | Phase 1 | 54 | Novartis PharmaceuticalsINDUSTRY | 5 | Dec 19, 2020 | clinicaltrials |
| NCT01822613 | Study of Safety & Efficacy of the Combination of LJM716 & BYL719 in Patients With Previously Treated Esophageal Squamous Cell Carcinoma (ESCC) | completed | Phase 1 | 48 | Novartis PharmaceuticalsINDUSTRY | 9 | Dec 19, 2020 | clinicaltrials |
| NCT02082210 | A Study of Emibetuzumab in Combination With Ramucirumab (LY3009806) in Participants With Advanced Cancer | completed | Phase 1 / Phase 2 | 97 | Eli Lilly and CompanyINDUSTRY | 1 | Dec 19, 2020 | clinicaltrials |
| NCT03377400 | Definitive CCRT Combined With Durvalumab and Tremelimumab for Inoperable Esophageal Cancer | unknown | Phase 2 | 40 | Samsung Medical CenterOTHER | 1 | Dec 17, 2020 | clinicaltrials |
| NCT03987815 | Neoadjuvant Nivolumab for Operable Esophageal Carcinoma | unknown | Phase 2 | 20 | Samsung Medical CenterOTHER | 1 | Dec 17, 2020 | clinicaltrials |
| NCT02890979 | Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease | completed | N/A | 11 | OHSU Knight Cancer InstituteOTHER | 1 | Nov 25, 2020 | clinicaltrials |
| NCT04644250 | Combination of Toripalimab and Neoadjuvant Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 32 | Wei RenOTHER | 1 | Nov 25, 2020 | clinicaltrials |
| NCT03474341 | Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer(PRIDE) | unknown | — | 200 | UMC UtrechtOTHER | 1 | Nov 16, 2020 | clinicaltrials |
| NCT02757391 | CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal Tumors | terminated | Phase 1 | 1 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 30, 2020 | clinicaltrials |
| NCT04602013 | Sintilimab Injection Combined With Concurrent CCRT in Locally Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 53 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Oct 26, 2020 | clinicaltrials |
| NCT01107639 | Radiation Therapy and Chemotherapy, With or Without Cetuximab, Followed by Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery | completed | Phase 3 | 297 | Swiss Cancer InstituteOTHER | 5 | Oct 20, 2020 | clinicaltrials |
| NCT04481100 | CCRT With Itraconazole in Locally Advanced Squamous Esophageal Cancer | unknown | Phase 2 | 38 | Hangzhou Cancer HospitalOTHER | 1 | Oct 14, 2020 | clinicaltrials |
| NCT03302403 | Clinical Study of Redirected Autologous T Cells With a Chimeric Antigen Receptor in Patients With Malignant Tumors | unknown | N/A | 18 | Kang YUOTHER | 1 | Oct 8, 2020 | clinicaltrials |
| NCT01364324 | Pharmacokinetics of Anti-tuberculosis Drugs in Gastrectomized Patients | completed | — | 40 | National Cancer Center, KoreaOTHER_GOV | 1 | Sep 25, 2020 | clinicaltrials |
| NCT04411589 | The Diagnostic Ability of White Light Endoscopy and Magnifying Endoscopy With Optical Enhancement System | unknown | N/A | 300 | Shandong UniversityOTHER | 1 | Sep 25, 2020 | clinicaltrials |
| NCT02606916 | Radiotherapy Combined With S-1/DDP for Elderly Esophageal Squamous Cell Cancer. | completed | Phase 2 | 42 | Sun Yat-sen UniversityOTHER | 1 | Sep 4, 2020 | clinicaltrials |
| NCT04522687 | Influence of Radiotherapy and Chemotherapy in the Value of Peripheral Blood Lymphocyte Subsets Among Thoracic Cancer | recruiting | — | 500 | Shanghai Cancer Hospital, ChinaOTHER | 1 | Aug 21, 2020 | clinicaltrials |
| NCT02658214 | Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors | completed | Phase 1 | 32 | AstraZenecaINDUSTRY | 2 | Aug 20, 2020 | clinicaltrials |
| NCT04520295 | ctDNA Screening in Advanced HER2 Positive Gastric Cancer | unknown | — | 100 | Ruijin HospitalOTHER | 1 | Aug 20, 2020 | clinicaltrials |
| NCT04517019 | Randomised Trial Evaluating the Benefit of a Fitness Tracker Based Workout During Radiotherapy(OnkoFit II) | unknown | N/A | 201 | University Hospital TuebingenOTHER | 1 | Aug 18, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Apr 29, 2021source: clinicaltrials