Clinical trial · Observational
Outcomes of Endoscopically Resected High-risk Mucosal and Low- and High-risk Submucosal Adenocarcinoma Arising in Barrett's Esophagus
Outcomes of Endoscopically Resected High-risk Mucosal Adenocarcinoma and Low- and High-risk Submucosal Adenocarcinoma Arising in Barrett's Esophagus: an International Multicenter Retrospective Cohort Study
NCT04818476CI-TRIAL-00050905unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to assess lymph node metastasis rate, distant metastasis rate, disease-specific mortality, and overall mortality in patients with Barrett's related T1b and high risk T1a esophageal adenocarcinoma (EAC) who underwent a diagnostic endoscopic resection.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adenocarcinoma Esophagus | Esophageal Adenocarcinoma | ALIAS | 0.90 |
| Barrett Esophagus | — | UNRESOLVED | — |
| High-risk Mucosal Esophageal Adenocarcinoma | — | UNRESOLVED | — |
| Submucosal Esophageal Adenocarcinoma | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| diagnostic endoscopic resection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- HR-T1a
- description
- Patients who weretreated by radical endoscopic resection for a high-risk mucosal EAC (HR-T1a N0M0)
- interventionNames
- Procedure: diagnostic endoscopic resection
- label
- LR-T1b
- description
- Patients who were treated by radical endoscopic resection for a low-risk submucosal EAC (LR-T1b N0M0)
- interventionNames
- Procedure: diagnostic endoscopic resection
- label
- HR-T1b
- description
- Patients who were treated by radical endoscopic resection for a high-risk submucosal EAC (HR-T1b N0M0)
- interventionNames
- Procedure: diagnostic endoscopic resection
Primary outcomes (4)
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: 1. Males or females, all ages 2. Endoscopic resection of a histologically proven high risk T1a, low risk T1b EAC, or high risk T1b EAC 3. Between 1/1/2008 and 1/1/2019 4. Endoscopic resection and endoscopic FU (or other treatment after ER) have taken place in the participating center 5. No written or oral refusal to use subject's data Exclusion Criterium: Objection against participation in this study
References
Publications (0)
Data not yet available
No reference posted for this study.