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Clinical trials
52 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03785964 | Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)(DeFi) | completed | Phase 3 | 142 | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY | 7 | Aug 20, 2026 | clinicaltrials |
| NCT02066181 | Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis | completed | Phase 3 | 87 | National Cancer Institute (NCI)NIH | 2 |
| Jun 24, 2026 |
| clinicaltrials |
| NCT02476305 | Evaluation of the Cryodestruction of Non Abdominopelvic Desmoid Tumors in Patients Progressing Despite Medical Treatment(CRYODESMO01) | completed | N/A | 50 | University Hospital, Strasbourg, FranceOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT02547831 | Tailored Beta-catenin Mutational Approach in Extra-abdominal Sporadic Desmoids Tumor Patients | completed | — | 100 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Sep 11, 2025 | clinicaltrials |
| NCT06258421 | Burden of Disease and Living Situation in Desmoid Patients(PROSa Desmoid) | completed | — | 100 | Technische Universität DresdenOTHER | 1 | Aug 24, 2025 | clinicaltrials |
| NCT02228889 | RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction | completed | N/A | 46 | Jeffrey JanisOTHER | 1 | Jun 6, 2025 | clinicaltrials |
| NCT03190174 | Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers | completed | Phase 1 / Phase 2 | 34 | Sarcoma Oncology Research Center, LLCOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT02076906 | MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors | completed | Phase 1 | 7 | AeRang KimOTHER | 1 | Jan 1, 2025 | clinicaltrials |
| NCT03802084 | A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor | completed | Phase 1 / Phase 2 | 24 | Hyo Song KimOTHER | 1 | May 13, 2024 | clinicaltrials |
| NCT01981551 | Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis | completed | Phase 2 | 17 | National Cancer Institute (NCI)NIH | 1 | Feb 6, 2024 | clinicaltrials |
| NCT06195085 | CT-guided Radioactive Iodine-125 Seed Implantation for Recurrent Desmoid Tumors | completed | — | 38 | Peking University Third HospitalOTHER | 1 | Jan 8, 2024 | clinicaltrials |
| NCT00928525 | Imatinib in Patients With Desmoid Tumor and Chondrosarcoma(Basket 1) | completed | Phase 2 | 35 | Italian Sarcoma GroupNETWORK | 1 | Oct 5, 2023 | clinicaltrials |
| NCT00919269 | Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma | completed | — | 150 | Children's Oncology GroupNETWORK | 7 | Oct 3, 2023 | clinicaltrials |
| NCT04289077 | Quality of Life of Patients With Desmoid-type Fibromatosis(QUALIFIED) | completed | — | 156 | Erasmus Medical CenterOTHER | 2 | Sep 7, 2023 | clinicaltrials |
| NCT01265030 | A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis | completed | Phase 1 / Phase 2 | 9 | MaineHealthOTHER | 1 | Jun 26, 2023 | clinicaltrials |
| NCT03459469 | Phase I, Open-label, Non-randomized Study to Evaluate Safety of BC2059 | completed | Phase 1 | 24 | Iterion TherapeuticsINDUSTRY | 2 | Mar 1, 2023 | clinicaltrials |
| NCT03966742 | Doxorubicin Eluting Intra-arterial Embolization for Aggressive Desmoid Fibromatosis | completed | Phase 2 | 8 | Rabin Medical CenterOTHER | 1 | Mar 25, 2022 | clinicaltrials |
| NCT00068419 | Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor | completed | Phase 2 | 70 | Children's Oncology GroupNETWORK | 1 | Feb 19, 2020 | clinicaltrials |
| NCT01137916 | Study to Evaluate Imatinib in Desmoid Tumors | completed | Phase 2 | 39 | Heidelberg UniversityOTHER | 1 | May 3, 2017 | clinicaltrials |
| NCT00287846 | Imatinib Mesylate in Treating Patients With Recurrent or Refractory Fibromatosis | completed | Phase 1 / Phase 2 | 40 | UNICANCEROTHER | 1 | Aug 30, 2016 | clinicaltrials |
| NCT01567046 | Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas | completed | — | 70 | Children's Oncology GroupNETWORK | 1 | May 17, 2016 | clinicaltrials |
| NCT00474994 | Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas | completed | Phase 2 | 53 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jan 20, 2016 | clinicaltrials |
| NCT00003019 | Vinblastine and Methotrexate in Treating Children With Desmoid Tumors | completed | Phase 2 | 28 | Children's Oncology GroupNETWORK | 3 | Jul 25, 2014 | clinicaltrials |
| NCT00030680 | Radiation Therapy in Treating Patients With Aggressive Fibromatoses | completed | Phase 2 | 44 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 7 | Aug 27, 2013 | clinicaltrials |
| NCT00002595 | Toremifene in Treating Patients With Desmoid Tumors | completed | Phase 2 | 72 | Advocate Lutheran General HospitalOTHER | 1 | Jul 10, 2013 | clinicaltrials |
| NCT01286662 | A Cohort Study of Patients Treated With Brachytherapy for Selected Desmoid Patients in Gardner Syndrome | completed | — | 105 | Triemli HospitalOTHER | 0 | Jan 31, 2011 | clinicaltrials |
Data updated 23 days agoSource updated Aug 20, 2026source: clinicaltrials