Subtype

Clear Cell Tumor with Melanocytic Differentiation and ACTIN-MITF Translocation

CI-CAN-00002384CCTMAMExplore in graph →

Non-malignant

NCIt: C204740

Data completeness0 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (no data yet)
Literature (no data yet)
Genomics (no data yet)
Evidence (no data yet)
Therapies (no data yet)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A MITF pathway-activated melanocytic tumor characterized by a cytogenetic translocation between ACTIN and MITF genes that results in ACTIN-MITF gene fusion. It presents as a single non-pigmented cutaneous nodule in the distal extremities or trunk. It is composed of large cells with clear cytoplasm that exhibit melanocytic differentiation and proliferate in the dermis without an intraepidermal component. Extension in the subcutaneous tissue is frequently seen. Atypical nuclear features may be present. It has an indolent clinical course.

Definition text as published by ncit-evs Curated

Data updated 23 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

MITF Pathway-Activated Melanocytic TumorSubtype

Children (2)

ncit

Anatomy

Anatomical sites

SkinC12470

Publications (all / 5y)

0 / 0

Evidence items

0

Genes / variants

0 / 0

Drugs (any / approved)

0 / 0

Genomic cohorts

0

Epidemiology / survival obs.

0 / 0

Data updated 19 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (2)

Clear Cell Neoplasm with Melanocytic Differentiation and ACTIN-MITF Translocationsynonym · NCIt
Skin Clear Cell Tumor with Melanocytic Differentiation and ACTIN-MITF Translocationsynonym · NCIt

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Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

No registry-level ancestor: burden figures are published for the mutually exclusive top-level site groups only, and this entity does not descend from one. Global figures (IARC / GLOBOCAN) stay under license review and SEER awaits credentials.

Active trials0countcurrent registry status · entity + descendantsclinicaltrialsComputednot in a current ranking snapshot
Recruiting trials0countstatus RECRUITING · entity + descendantsclinicaltrialsComputednot in a current ranking snapshot
Curated evidence items0countaccepted CIViC items · entity + descendantscivicComputednot in a current ranking snapshot
Publications, last 12 months0countPubMed records · stored query · 12-month windowpubmedComputednot in a current ranking snapshot
Genomic cohorts0countopen GDC projects · entity + descendantsgdcComputednot in a current ranking snapshot

Data updated 19 hours agoSource updated unknownregistry figures: none · counters aggregate over descendants