Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,060 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01702792 | Derivation of Tumor Specific Hybridomas | terminated | Phase 1 | 1 | Dartmouth-Hitchcock Medical CenterOTHER | 0 | Apr 4, 2018 | clinicaltrials |
| NCT02365662 | A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor | terminated | Phase 1 | 46 | AbbVieINDUSTRY | 2 | Mar 30, 2018 | clinicaltrials |
| NCT00003471 | Antineoplaston Therapy in Treating Patients With Low-Grade Astrocytoma | terminated | Phase 2 | 7 | Burzynski Research InstituteOTHER | 1 | Mar 22, 2018 | clinicaltrials |
| NCT02654041 | Study of Induction of Hypothyroxinemia Adjunct to Conventional Therapies in GBM Patients | terminated | Phase 2 | 3 | Musli Thyropeutics Ltd.INDUSTRY | 1 | Mar 22, 2018 | clinicaltrials |
| NCT00003472 | Antineoplaston Therapy in Treating Patients With Recurrent or Refractory Oligodendroglioma | terminated | Phase 2 | 13 | Burzynski Research InstituteOTHER | 1 | Mar 21, 2018 | clinicaltrials |
| NCT00003535 | Antineoplaston Therapy in Treating Children With Recurrent or Refractory High-Grade Glioma | terminated | Phase 2 | 9 | Burzynski Research InstituteOTHER | 1 | Mar 21, 2018 | clinicaltrials |
| NCT00096265 | Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer | terminated | Phase 3 | 126 | National Cancer Institute (NCI)NIH | 2 | Mar 9, 2018 | clinicaltrials |
| NCT02254954 | Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastoma | terminated | Phase 1 | 30 | ActelionINDUSTRY | 1 | Feb 27, 2018 | clinicaltrials |
| NCT02617862 | PCI Imaging System in Pediatric Ophthalmology | terminated | N/A | 6 | Brenda GallieOTHER | 1 | Feb 12, 2018 | clinicaltrials |
| NCT02047214 | Safety & Efficacy Study of TPI 287 + Avastin in Adults With Glioblastoma That Progressed Following Prior Avastin Therapy | terminated | Phase 2 | 17 | Cortice Biosciences, Inc.INDUSTRY | 1 | Jan 31, 2018 | clinicaltrials |
| NCT01821443 | A Single Arm Study of Neurocognitive Outcomes in Patients With Brain Metastases Managed With Stereotactic Radiosurgery (SRS) | terminated | N/A | 10 | University of California, San FranciscoOTHER | 1 | Jan 23, 2018 | clinicaltrials |
| NCT00623077 | MT2004-30: Tomotherapy for Solid Tumors | terminated | Phase 1 | 23 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Dec 5, 2017 | clinicaltrials |
| NCT00003926 | Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors | terminated | Phase 1 | 13 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Nov 29, 2017 | clinicaltrials |
| NCT00929669 | Effect of Pasireotide Long Acting Release (LAR) on Gonadotroph Adenomas(LAR) | terminated | Phase 2 | 2 | University of PennsylvaniaOTHER | 1 | Nov 28, 2017 | clinicaltrials |
| NCT01339039 | Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Glioma | terminated | Phase 1 | 26 | Patrick Y. Wen, MDOTHER | 1 | Nov 17, 2017 | clinicaltrials |
| NCT02510950 | Neoepitope-based Personalized Vaccine Approach in Patients With Newly Diagnosed Glioblastoma | terminated | Phase 1 | 1 | Washington University School of MedicineOTHER | 1 | Nov 17, 2017 | clinicaltrials |
| NCT01666600 | NOA-12: BIBF1120 and R-RT in Glioblastoma | terminated | Phase 1 / Phase 2 | 63 | Prof. Dr. Wolfgang WickOTHER | 1 | Nov 1, 2017 | clinicaltrials |
| NCT02329795 | Image-derived Prediction of Response to Chemo-radiation in Glioblastoma(IDEPREG) | terminated | — | 16 | Rigshospitalet, DenmarkOTHER | 1 | Oct 12, 2017 | clinicaltrials |
| NCT01508117 | Phase II Axitinib (AG-013736) in Elderly Glioblastoma Multiforme (GBM) Patients | terminated | Phase 2 | 1 | University of CincinnatiOTHER | 1 | Sep 19, 2017 | clinicaltrials |
| NCT02279992 | Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases(LevitraCarbo) | terminated | Early Phase 1 | 7 | Cedars-Sinai Medical CenterOTHER | 1 | Sep 11, 2017 | clinicaltrials |
| NCT00003469 | Antineoplaston Therapy in Treating Children With Rhabdoid Tumor of the Central Nervous System | terminated | Phase 2 | 4 | Burzynski Research InstituteOTHER | 1 | Aug 24, 2017 | clinicaltrials |
| NCT00003476 | Antineoplaston Therapy in Treating Children With Primary Malignant Brain Tumors | terminated | Phase 2 | 8 | Burzynski Research InstituteOTHER | 1 | Aug 24, 2017 | clinicaltrials |
| NCT00003483 | Antineoplaston Therapy in Treating Patients With Meningioma | terminated | Phase 2 | 3 | Burzynski Research InstituteOTHER | 1 | Aug 24, 2017 | clinicaltrials |
| NCT00326872 | AZD2171 in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibroma and/or Neurofibroma Near the Spine | terminated | Phase 2 | 26 | National Cancer Institute (NCI)NIH | 1 | Aug 18, 2017 | clinicaltrials |
| NCT01263821 | Image Guided Therapy in the Treatment of Gliomas | terminated | N/A | 15 | NYU Langone HealthOTHER | 1 | Aug 4, 2017 | clinicaltrials |
| NCT02988726 | Antineoplaston Therapy in Treating Patients With Neurofibroma and Schwannoma | terminated | Phase 2 | 3 | Burzynski Research InstituteOTHER | 1 | Jul 26, 2017 | clinicaltrials |
| NCT01526837 | Bevacizumab (Avastin) Into the Tumor Resection Cavity in Subjects With Glioblastoma Multiforme at First Recurrence | terminated | Phase 1 | 1 | Brain & Spine Surgeons of New YorkOTHER | 1 | Jul 12, 2017 | clinicaltrials |
| NCT00112866 | Cilengitide in Treating Patients Who Are Undergoing Surgery for Recurrent or Progressive Glioblastoma Multiforme | terminated | Phase 2 | 30 | National Cancer Institute (NCI)NIH | 1 | Jun 14, 2017 | clinicaltrials |
| NCT00638963 | Temozolomide as a Prophylaxis Against Brain Recurrence in Participants With Metastatic Breast Cancer (P05225 AM2)(STOP) | terminated | Phase 2 | 6 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Jun 14, 2017 | clinicaltrials |
| NCT02039778 | Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade Glioma(STRONG) | terminated | N/A | 4 | Beth Israel Medical CenterOTHER | 1 | Jun 5, 2017 | clinicaltrials |
| NCT01310855 | Cediranib Maleate With or Without Gefitinib in Treating Patients With Recurrent or Progressive Glioblastoma | terminated | Phase 2 | 38 | University College, LondonOTHER | 1 | May 31, 2017 | clinicaltrials |
| NCT02648633 | Stereotactic Radiosurgery With Nivolumab and Valproate in Patients With Recurrent Glioblastoma | terminated | Phase 1 | 4 | University of VirginiaOTHER | 1 | May 31, 2017 | clinicaltrials |
| NCT00034697 | Study of Temozolomide in the Treatment of Brain Metastasis From Non-small-cell Lung Cancer (Study P02143) | terminated | Phase 2 | 24 | Merck Sharp & Dohme LLCINDUSTRY | 0 | May 23, 2017 | clinicaltrials |
| NCT02129335 | Stress, Exercise Behavior and Survival in Patients With Newly Diagnosed Glioblastoma and in a Close Partner(TOGETHER) | terminated | — | 12 | University Hospital, Basel, SwitzerlandOTHER | 1 | May 17, 2017 | clinicaltrials |
| NCT01122901 | Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma | terminated | Phase 2 | 47 | National Cancer Institute (NCI)NIH | 1 | May 3, 2017 | clinicaltrials |
| NCT00710151 | Neurotoxicity in Primary Central Nervous System Lymphoma (PCNSL): An International Observational Study of Cognition in Long Term Survivors | terminated | — | 80 | OHSU Knight Cancer InstituteOTHER | 2 | Apr 21, 2017 | clinicaltrials |
| NCT00769093 | Assessing Dynamic Magnetic Resonance (MR) Imaging in Patients With Recurrent High Grade Glioma Receiving Chemotherapy | terminated | Phase 1 | 6 | OHSU Knight Cancer InstituteOTHER | 1 | Apr 21, 2017 | clinicaltrials |
| NCT01996527 | 3T MRI Biomarkers of Glioma Treatment Response | terminated | Early Phase 1 | 7 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | Apr 17, 2017 | clinicaltrials |
| NCT00974623 | Bone Graft Materials Observational Registry(APPROACH-001) | terminated | — | 329 | Baxter Healthcare CorporationINDUSTRY | 3 | Apr 5, 2017 | clinicaltrials |
| NCT02967380 | Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases | terminated | N/A | 14 | University of Southern CaliforniaOTHER | 1 | Mar 27, 2017 | clinicaltrials |
| NCT00360828 | Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas | terminated | Phase 2 | 10 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Mar 23, 2017 | clinicaltrials |
| NCT02175745 | 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas | terminated | N/A | 2 | Erik MittraOTHER | 1 | Mar 20, 2017 | clinicaltrials |
| NCT01944943 | Phase II Study of Vismodegib in Patients With Refractory or Relapsed B-cell Lymphoma or Chronic Lymphocytic Leukemia(VISMOLY) | terminated | Phase 2 | 31 | The Lymphoma Academic Research OrganisationOTHER | 1 | Mar 13, 2017 | clinicaltrials |
| NCT01902771 | Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors | terminated | Phase 1 | 1 | Edward ZigaOTHER | 1 | Mar 10, 2017 | clinicaltrials |
| NCT00456612 | Radiosurgery for Glioblastoma Multiforme | terminated | Phase 1 / Phase 2 | 4 | Beth Israel Deaconess Medical CenterOTHER | 1 | Mar 6, 2017 | clinicaltrials |
| NCT01642823 | Cancer Biology of Retinoblastoma | terminated | — | 8 | Stanford UniversityOTHER | 2 | Mar 6, 2017 | clinicaltrials |
| NCT00582608 | Tumor Detection Using Iodine-131-Labeled Monoclonal Antibody 8H9 | terminated | N/A | 12 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 1, 2017 | clinicaltrials |
| NCT00171938 | Open-label Trial of Imatinib Mesylate in Patients With Unresectable Recurrent Glioblastoma Multiforme Expressing PDGFR (Platelet Derived Growth Factor Receptors) | terminated | Phase 2 | 30 | NovartisINDUSTRY | 1 | Feb 24, 2017 | clinicaltrials |
| NCT00437957 | Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain Metastases | terminated | Phase 1 | 10 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Feb 23, 2017 | clinicaltrials |
| NCT01148966 | Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors | terminated | Phase 1 | 6 | University of WashingtonOTHER | 1 | Feb 15, 2017 | clinicaltrials |
Data updated 23 days agoSource updated Apr 4, 2018source: clinicaltrials