Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,347 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,063 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03250520 | Application of Palliative Treatment in Children With Brain Stem Glioma and Recurrent High-grade Tumors in the Central Nervous System With the Nanomaterial NPt-Ca | completed | Early Phase 1 | 8 | Hospital Infantil de Mexico Federico GomezOTHER | 1 | Feb 28, 2023 | clinicaltrials |
| NCT01792310 | A Phase 1/2A Study of LAM561 in Adult Patients With Advanced Solid Tumours | completed | Phase 1 / Phase 2 | 54 | Laminar PharmaceuticalsINDUSTRY | 2 | Feb 21, 2023 |
| clinicaltrials |
| NCT02462629 | Study of BLZ-100 in Pediatric Subjects With CNS Tumors | completed | Phase 1 | 29 | Blaze Bioscience Inc.INDUSTRY | 1 | Feb 21, 2023 | clinicaltrials |
| NCT03867123 | A Study to Evaluate the Safety of LAM561 Added to Standard of Care in Newly-diagnosed Glioblastoma Patients | completed | Phase 1 | 18 | Laminar PharmaceuticalsINDUSTRY | 1 | Feb 21, 2023 | clinicaltrials |
| NCT04334863 | WP1066 in Children With Refractory and Progressive or Recurrent Malignant Brain Tumors | completed | Phase 1 | 10 | Emory UniversityOTHER | 1 | Feb 21, 2023 | clinicaltrials |
| NCT02022384 | Immunophenotyping From Blood of Patients With Malignant Gliomas | completed | — | 50 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Feb 16, 2023 | clinicaltrials |
| NCT00100802 | Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas | completed | Phase 2 | 118 | Children's Oncology GroupNETWORK | 1 | Feb 15, 2023 | clinicaltrials |
| NCT02997423 | Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM) | completed | — | 153 | University of IowaOTHER | 1 | Feb 13, 2023 | clinicaltrials |
| NCT03273712 | Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC) | completed | Phase 2 | 39 | University of IowaOTHER | 1 | Feb 9, 2023 | clinicaltrials |
| NCT05717335 | Observational Pilot Study With TachoSil as a Ventricular Sealant | completed | — | 20 | Germans Trias i Pujol HospitalOTHER | 1 | Feb 8, 2023 | clinicaltrials |
| NCT02296580 | A Feasibility Study of the Nativis Voyager® System in Patients With Recurrent Glioblastoma Multiforme (GBM) | completed | N/A | 37 | Nativis, Inc.INDUSTRY | 2 | Feb 2, 2023 | clinicaltrials |
| NCT03276286 | Nativis Voyager for Newly Diagnosed GBM(NAT109) | completed | N/A | 37 | Nativis, Inc.INDUSTRY | 1 | Feb 2, 2023 | clinicaltrials |
| NCT02388659 | Clinical Development of Cancer-Specific MRS Biomarkers in Malignant Gliomas | completed | — | 142 | University of Texas Southwestern Medical CenterOTHER | 1 | Jan 31, 2023 | clinicaltrials |
| NCT05103735 | Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity | completed | — | 170 | Azienda Sanitaria-Universitaria Integrata di UdineOTHER | 1 | Jan 31, 2023 | clinicaltrials |
| NCT04170777 | Perfexion Registration Using CBCT | completed | — | 1,250 | University Health Network, TorontoOTHER | 1 | Jan 26, 2023 | clinicaltrials |
| NCT03072134 | Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma | completed | Phase 1 | 12 | Northwestern UniversityOTHER | 1 | Jan 20, 2023 | clinicaltrials |
| NCT04075370 | Exploring Compensation to Maintain Cognitive Function in Adults Newly Diagnosed With Brain Cancer | completed | — | 33 | Duke UniversityOTHER | 1 | Jan 20, 2023 | clinicaltrials |
| NCT02829931 | Hypofractionated Stereotactic Irradiation With Nivolumab, Ipilimumab and Bevacizumab in Patients With Recurrent High Grade Gliomas | completed | Phase 1 | 33 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Jan 19, 2023 | clinicaltrials |
| NCT04584827 | Evaluation of Lactate in Patients Undergoing Glial and Non Glial Mass Surgery With Craniotomy | completed | — | 100 | Trakya UniversityOTHER | 1 | Jan 19, 2023 | clinicaltrials |
| NCT03888014 | Intraoperative Fluorescence With Augmented Reality | completed | — | 7 | Cedars-Sinai Medical CenterOTHER | 1 | Jan 18, 2023 | clinicaltrials |
| NCT04430842 | Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S | completed | Phase 1 | 15 | Quadriga Biosciences, Inc.INDUSTRY | 1 | Jan 18, 2023 | clinicaltrials |
| NCT04657315 | Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma Patients(MSC11FCD-GBM) | completed | Phase 1 / Phase 2 | 10 | CHA UniversityOTHER | 1 | Jan 18, 2023 | clinicaltrials |
| NCT03355794 | A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG) | completed | Phase 1 | 19 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Jan 13, 2023 | clinicaltrials |
| NCT02311920 | Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma | completed | Phase 1 | 32 | National Cancer Institute (NCI)NIH | 1 | Jan 10, 2023 | clinicaltrials |
| NCT02017964 | Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma | completed | Phase 2 | 26 | Children's Oncology GroupNETWORK | 4 | Jan 9, 2023 | clinicaltrials |
| NCT00312728 | A Study of Bevacizumab in Combination With First- or Second-Line Therapy in Subjects With Treated Brain Metastases Due to Non-Squamous NSCLC (PASSPORT) | completed | Phase 2 | 115 | Genentech, Inc.INDUSTRY | 0 | Jan 6, 2023 | clinicaltrials |
| NCT05671016 | Brain Imaging to Predict Toxicity in Elderly Patients After Radiotherapy(BRITER) | completed | — | 125 | Brighton and Sussex University Hospitals NHS TrustOTHER | 1 | Jan 4, 2023 | clinicaltrials |
| NCT01730950 | Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma | completed | Phase 2 | 182 | Radiation Therapy Oncology GroupNETWORK | 1 | Dec 29, 2022 | clinicaltrials |
| NCT01974804 | Assessment of Early Treatment Response by Diffusion and Perfusion MRI in Patients With Brain Metastasis | completed | — | 30 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 29, 2022 | clinicaltrials |
| NCT02849171 | Assessing 11C-Choline (11C-CH) PET to Distinguish True Tumor Progression From Pseudoprogression in High-grade Gliomas | completed | N/A | 8 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 29, 2022 | clinicaltrials |
| NCT03520504 | Study of Proton Radiation to the Brain and Spinal Cord for Patients With Leptomeningeal Metastases | completed | Phase 1 | 24 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 23, 2022 | clinicaltrials |
| NCT04444427 | Evaluation of GLR2007 for Advanced Solid Tumors | completed | Phase 1 / Phase 2 | 19 | Gan and Lee Pharmaceuticals, USAINDUSTRY | 1 | Dec 23, 2022 | clinicaltrials |
| NCT02037945 | 18F-Fluorocholine (18F-FCho) to Distinguish Necrosis From Recurrence in Brain Metastases | completed | N/A | 19 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 19, 2022 | clinicaltrials |
| NCT01177397 | Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma | completed | Phase 1 / Phase 2 | 226 | CelgeneINDUSTRY | 4 | Dec 13, 2022 | clinicaltrials |
| NCT04782596 | Transnasal Endoscopic Pituitary Surgery - the Effect of Posterior Nasal Septum Resection on Nasal Functions | completed | N/A | 30 | University Hospital OstravaOTHER | 1 | Dec 7, 2022 | clinicaltrials |
| NCT05641636 | Cardiovascular Disorders and Risk Factors in Childhood Cranial and Craniospinal Tumors Survivors | completed | — | 60 | I.M. Sechenov First Moscow State Medical UniversityOTHER | 1 | Dec 7, 2022 | clinicaltrials |
| NCT04114370 | Evaluation of 18F-fluciclovine (FACBC) PET/MR Uptake in Participants With Glioma(FACBC) | completed | Early Phase 1 | 9 | James MountzOTHER | 1 | Dec 6, 2022 | clinicaltrials |
| NCT04934579 | Rituximab,Methotrexate and Lenalidomide in Newly Diagnosed Primary Central Nervous System Lymphoma | completed | Phase 2 | 17 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Nov 23, 2022 | clinicaltrials |
| NCT01301430 | Parvovirus H-1 (ParvOryx) in Patients With Progressive Primary or Recurrent Glioblastoma Multiforme.(ParvOryx01) | completed | Phase 1 / Phase 2 | 18 | Oryx GmbH & Co. KGINDUSTRY | 1 | Nov 21, 2022 | clinicaltrials |
| NCT01647971 | Study of the Efficacy and Safety of Ublituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma | completed | Phase 1 / Phase 2 | 39 | TG Therapeutics, Inc.INDUSTRY | 1 | Nov 21, 2022 | clinicaltrials |
| NCT04132843 | Novel MRI Techniques for the Characterization and Treatment Assessment of High Grade Brain Lesions | completed | N/A | 6 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 21, 2022 | clinicaltrials |
| NCT04597801 | Comparison of Fluorescein-INtra-VItal Microscopy Versus Conventional Frozen Section Diagnosis for intraOperative Histopathological Evaluation(INVIVO) | completed | Phase 2 | 210 | Technical University of MunichOTHER | 1 | Nov 10, 2022 | clinicaltrials |
| NCT01865162 | Ketogenic Diet as Adjunctive Treatment in Refractory/End-stage Glioblastoma Multiforme: a Pilot Study(KGDinGBM) | completed | Phase 1 | 6 | Mid-Atlantic Epilepsy and Sleep Center, LLCOTHER | 1 | Nov 9, 2022 | clinicaltrials |
| NCT03291977 | Interest of Fluorescein in Fluorescence-guided Resection of Gliomas (FLEGME)(FLEGME) | completed | Phase 3 | 51 | Rennes University HospitalOTHER | 1 | Nov 9, 2022 | clinicaltrials |
| NCT02115139 | GEM STUDY: Radiation And Yervoy in Patients With Melanoma and Brain Metastases(GRAY-B) | completed | Phase 2 | 58 | Grupo Español Multidisciplinar de MelanomaOTHER | 1 | Nov 8, 2022 | clinicaltrials |
| NCT03668847 | DM-CHOC-PEN for Brain Tumors in AYA Subjects | completed | Phase 2 | 20 | DEKK-TEC, Inc.INDUSTRY | 1 | Nov 8, 2022 | clinicaltrials |
| NCT04860934 | Dual Task Training On Children With Ataxia After Medulloblastoma Resection | completed | N/A | 30 | Children's Cancer Hospital Egypt 57357OTHER | 1 | Nov 8, 2022 | clinicaltrials |
| NCT02274987 | Molecular Profiling for Individualized Treatment Plan for DIPG | completed | N/A | 38 | University of California, San FranciscoOTHER | 1 | Nov 4, 2022 | clinicaltrials |
| NCT03666507 | Vegetative Monitoring During Brainstem-associated Surgery | completed | — | 103 | University Hospital TuebingenOTHER | 1 | Nov 4, 2022 | clinicaltrials |
| NCT02858895 | Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma | completed | Phase 2 | 47 | Medicenna Therapeutics, Inc.INDUSTRY | 1 | Oct 24, 2022 | clinicaltrials |
Data updated 24 days agoSource updated Feb 28, 2023source: clinicaltrials