Clinical trial · Observational
Evaluation of Lactate in Patients Undergoing Glial and Non Glial Mass Surgery With Craniotomy
NCT04584827CI-TRIAL-00063310completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to determine the effects of the level of metabolites used in routine on mortality and morbidity in patients who will undergo intracranial surgery with craniotomy.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Tumor | Brain Neoplasm | ALIAS | 0.90 |
| Lactate | — | UNRESOLVED | — |
| Post-Op Complication | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Glasgow Outcome Scale | Other | — | UNRESOLVED |
| lactate level | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- complication positive (up to 30 days after surgery)
- description
- Complications: * Moderate to severe intracerebral hemorrhage confirmed in a brain CT scan (Midline shift in brain imaging ≥ 3 mm), * İntracranial hypertension requiring post op surgical drainage, * Status epilepticus or seizures, * The need for tracheal intubation or use of mechanical ventilation after surgery, * Decrease in GKS, * Unmanageable agitation that requires restriction or sedation, * Need for respiratory failure and oxygen therapy, * Unexpected serious motor deficit * Died
- interventionNames
- Other: lactate level
- Other: Glasgow Outcome Scale
- label
- complication negative (up to 30 days after surgery)
- description
- No complications are seen within 30 days and the patient is healthy
- interventionNames
- Other: lactate level
- Other: Glasgow Outcome Scale
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Having an intracranial mass operation with craniotomy 2. No history of congestive heart failure 3. No kidney and liver dysfunction 4. Not pregnant 5. Not taking inotropic drugs during the operation 6. Receiving less than four red blood product replacements during the operation Exclusion Criteria: 1. Patients with a history of congestive heart failure 2. Patients with kidney and liver dysfunction 3. Patients who need an inotropic agent to adjust blood pressure during the operation 4. Patients who have undergone four or more red blood product transfusions during the operation 5. Pregnant patients
References
Publications (0)
Data not yet available
No reference posted for this study.