Hematologic Malignancy
B-Cell Neoplasm
CI-CAN-00000470Explore in graph →
HematologicNon-malignant2,097 active trials46 approved drugs301 evidence items
- NCIt
- C27907
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Hematologic Malignancy
CI-CAN-00000470Explore in graph →
Genomics
29 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
205 cases with simple somatic mutation data · 211 cases total · 2026-01-08 · mapped to Multiple Myeloma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | KRAS |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 45 |
| 205 |
| 22% |
| cbioportal |
| 2 | NRAS | Ssm | 37 | 205 | 18% | cbioportal |
| 3 | DIS3 | Ssm | 19 | 205 | 9.3% | cbioportal |
| 5 | ZNF717 | Ssm | 17 | 205 | 8.3% | cbioportal |
| 4 | TTN | Ssm | 17 | 205 | 8.3% | cbioportal |
| 6 | TENT5C | Ssm | 15 | 205 | 7.3% | cbioportal |
| 7 | TP53 | Ssm | 15 | 205 | 7.3% | cbioportal |
| 8 | BRAF | Ssm | 13 | 205 | 6.3% | cbioportal |
| 9 | MUC16 | Ssm | 13 | 205 | 6.3% | cbioportal |
| 11 | RYR2 | Ssm | 11 | 205 | 5.4% | cbioportal |
| 10 | LRP1B | Ssm | 11 | 205 | 5.4% | cbioportal |
| 12 | FAT3 | Ssm | 10 | 205 | 4.9% | cbioportal |
| 15 | HYDIN | Ssm | 9 | 205 | 4.4% | cbioportal |
| 13 | DNAH5 | Ssm | 9 | 205 | 4.4% | cbioportal |
| 16 | NEB | Ssm | 9 | 205 | 4.4% | cbioportal |
| 17 | TRIO | Ssm | 9 | 205 | 4.4% | cbioportal |
| 14 | DNAH9 | Ssm | 9 | 205 | 4.4% | cbioportal |
| 18 | CSMD2 | Ssm | 8 | 205 | 3.9% | cbioportal |
| 21 | SVIL | Ssm | 8 | 205 | 3.9% | cbioportal |
| 20 | KALRN | Ssm | 8 | 205 | 3.9% | cbioportal |
| 19 | GRIA2 | Ssm | 8 | 205 | 3.9% | cbioportal |
| 28 | HMCN1 | Ssm | 7 | 205 | 3.4% | cbioportal |
| 30 | SI | Ssm | 7 | 205 | 3.4% | cbioportal |
| 29 | NRXN1 | Ssm | 7 | 205 | 3.4% | cbioportal |
| 23 | CCND1 | Ssm | 7 | 205 | 3.4% | cbioportal |
| 31 | TRAF3 | Ssm | 7 | 205 | 3.4% | cbioportal |
| 22 | ADAMTS9 | Ssm | 7 | 205 | 3.4% | cbioportal |
| 32 | USH2A | Ssm | 7 | 205 | 3.4% | cbioportal |
| 24 | CHD3 | Ssm | 7 | 205 | 3.4% | cbioportal |
| 33 | ZFHX4 | Ssm | 7 | 205 | 3.4% | cbioportal |
Data updated 22 days agoSource updated 2026-01-08