Hematologic Malignancy
Alkylating Agent-Related Acute Myeloid Leukemia and Myelodysplastic Syndrome
CI-CAN-00001774Explore in graph →
Hematologic1 active trials
- NCIt
- C27913
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Hematologic Malignancy
CI-CAN-00001774Explore in graph →
Data completeness1 / 7 dimensions
Computed from entity_counters.completeness · refreshed after each connector run
Definition
Acute myeloid leukemias and myelodysplastic syndromes arising as a result of the mutagenic effect of alkylating agents that are used for the treatment of malignant tumors. Patients usually develop a myelodysplastic syndrome which may evolve to a higher grade myelodysplastic syndrome or acute myeloid leukemia. A minority of patients present with an acute myeloid leukemia. Clonal cytogenetic abnormalities are frequently present and usually are unbalanced translocations or deletions of chromosomes 5 and 7. Patients with acute myeloid leukemia usually do not respond to treatment and have an unfavorable clinical outcome.
Data updated 22 days agoSource updated 26.08e
Taxonomy
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Parents
Anatomy
Data updated 28 minutes agoSource updated unknowncounters aggregate over descendants
Names
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Key figures
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Data updated 28 minutes agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants