Hematologic Malignancy
Acute Lymphoblastic Leukemia
CI-CAN-00000400ALLExplore in graph →
Hematologic546 active trials12 approved drugs43 evidence items
- NCIt
- C3167
- DOID
- 9952
- MeSH
- D054198
- Other
- 3 more codes
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Hematologic Malignancy
CI-CAN-00000400ALLExplore in graph →
Clinical trials
2,037 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (268)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04614935 | Adherence and Outcomes in Functional Constipation With a Constipation Action Plan | completed | N/A | 38 | University of Alabama at BirminghamOTHER | 1 | Apr 15, 2022 | clinicaltrials |
| NCT02670252 | BuCY vs TBICY Conditioning Regimen for Standard-risk ALL Undergoing Allo-HSCT | completed | Phase 3 | 550 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Apr 8, 2022 | clinicaltrials |
| NCT02566395 | Stem Cell Transplantation From HLA Partially-Matched Related Donors for Patients With Hematologic Malignancies | completed | Phase 3 | 10 | Northwell HealthOTHER | 1 | Apr 7, 2022 | clinicaltrials |
| NCT04014764 | Collect and Assess Tissue Samples From Subjects With Hematologic Malignancy((ANSWer)) | completed | — | 119 | Notable LabsINDUSTRY | 3 | Apr 5, 2022 | clinicaltrials |
| NCT01411267 | AC220 for Children With Relapsed/Refractory ALL or AML | completed | Phase 1 | 24 | Therapeutic Advances in Childhood Leukemia ConsortiumOTHER | 1 | Apr 4, 2022 | clinicaltrials |
| NCT03187977 | Cognitive Intervention at the End of Therapy for Survivors of Childhood ALL Treated on TOTXVI | completed | N/A | 50 | St. Jude Children's Research HospitalOTHER | 1 | Mar 28, 2022 | clinicaltrials |
| NCT04888468 | Phase I Study of pCAR-19B in the Treatment of CD19-positive Relapsed/Refractory B-ALL in Children and Adolescents | completed | Phase 1 | 9 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | Mar 18, 2022 | clinicaltrials |
| NCT02293109 | Carfilzomib and Hyper-CVAD in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoma | completed | Phase 1 | 10 | Mehrdad Abedi, MDOTHER | 1 | Mar 10, 2022 | clinicaltrials |
| NCT02369653 | A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase | completed | Phase 3 | 512 | Bristol-Myers SquibbINDUSTRY | 12 | Mar 8, 2022 | clinicaltrials |
| NCT02730312 | PH 1 Study to Evaluate Safety and Tolerability of XmAb14045 in Patients With CD123-expressing Hematologic Malignancies | completed | Phase 1 | 120 | Xencor, Inc.INDUSTRY | 1 | Mar 8, 2022 | clinicaltrials |
| NCT04327037 | Safety of Expanded Haploidentical Natural Killer Cells for Leukemia | completed | Phase 1 | 10 | Belarusian Research Center for Pediatric Oncology, Hematology and ImmunologyOTHER | 1 | Mar 2, 2022 | clinicaltrials |
| NCT05223023 | Opinions of Physiotherapists Working in the Area of Pediatric Rehabilitation(physio) | completed | — | 83 | Kahramanmaras Sutcu Imam UniversityOTHER | 1 | Feb 18, 2022 | clinicaltrials |
| NCT01518517 | GRASPA (Erythrocytes Encapsulating L-asparaginase) in Patients With Relapse of Acute Lymphoblastic Leukemia(GRASPIVOTALL) | completed | Phase 2 / Phase 3 | 85 | ERYtech PharmaINDUSTRY | 2 | Feb 2, 2022 | clinicaltrials |
| NCT02914977 | Low-Dose Daunorubicin in Relapsed/Refractory Acute Leukemia | completed | Phase 1 | 18 | Tara LinOTHER | 1 | Jan 14, 2022 | clinicaltrials |
| NCT05190952 | Dexamethasone & Ketamine as Adjuvants to Bupivacaine for Incisional Infiltration in Pediatric Abdominal Operations | completed | N/A | 150 | Ain Shams UniversityOTHER | 1 | Jan 13, 2022 | clinicaltrials |
| NCT02083250 | Fludarabine Phosphate, Clofarabine, and Busulfan With Vorinostat in Treating Patients With Acute Leukemia in Remission or Relapse Undergoing Donor Stem Cell Transplant | completed | Phase 1 | 70 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 6, 2022 | clinicaltrials |
| NCT05176119 | Nalbuphine Versus Ketamine for Prevention of Emergence Agitation After Sevoflurane in Children Undergoing Tonsillectomy | completed | Phase 4 | 90 | Ain Shams UniversityOTHER | 1 | Jan 4, 2022 | clinicaltrials |
| NCT03359421 | Trauma Routing Algorithm for Pediatrics(TRAP) | completed | — | 4,801 | Wake Forest University Health SciencesOTHER | 1 | Dec 10, 2021 | clinicaltrials |
| NCT01597778 | Double Cord Versus Haploidentical (BMT CTN 1101) | completed | Phase 3 | 368 | Medical College of WisconsinOTHER | 1 | Dec 1, 2021 | clinicaltrials |
| NCT01641107 | Phase II Front-line Ponatinib in Adult Philadelphia+/BCR-ABL+ Acute Lymphoblastic Leukemia.(LAL1811) | completed | Phase 2 | 44 | Incyte CorporationINDUSTRY | 1 | Nov 30, 2021 | clinicaltrials |
| NCT05032716 | EFFECT OF TREADMILL TRAINING ON BALANCE AFTER CHEMOTHERAPY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA | completed | N/A | 40 | Cairo UniversityOTHER | 1 | Nov 17, 2021 | clinicaltrials |
| NCT00412360 | Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501) | completed | Phase 3 | 224 | Medical College of WisconsinOTHER | 3 | Oct 28, 2021 | clinicaltrials |
| NCT05091151 | Intranasal Dexmedetomidine Sedation at Dose of 2 mcg/kg Versus 4 mcg/kg in Children Undergoing MRI | completed | N/A | 94 | Indonesia UniversityOTHER | 1 | Oct 25, 2021 | clinicaltrials |
| NCT03263637 | Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies | completed | Phase 1 | 44 | AstraZenecaINDUSTRY | 3 | Oct 22, 2021 | clinicaltrials |
| NCT04399863 | ETOILE : A Feasibility Study in Pediatric Patient Education(ETOILE) | completed | N/A | 10 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Oct 18, 2021 | clinicaltrials |
| NCT01523782 | Administration of GRASPA (Suspension of Erythrocytes Encapsulating L-asparaginase) in Elderly Patients With First Line Acute Lymphoblastic Leukemia | completed | Phase 2 | 30 | ERYtech PharmaINDUSTRY | 0 | Oct 15, 2021 | clinicaltrials |
| NCT02808442 | Study of UCART19 in Pediatric Patients With Relapsed/Refractory B Acute Lymphoblastic Leukemia(PALL) | completed | Phase 1 | 13 | Institut de Recherches Internationales ServierOTHER | 4 | Oct 8, 2021 | clinicaltrials |
| NCT02746952 | Dose Escalation Study of UCART19 in Adult Patients With Relapsed / Refractory B-cell Acute Lymphoblastic Leukaemia(CALM) | completed | Phase 1 | 25 | Institut de Recherches Internationales ServierOTHER | 4 | Oct 1, 2021 | clinicaltrials |
| NCT02374333 | Pilot Study of Redirected Autologous T Cells Engineered to Contain Humanized Anti-CD19 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma Previously Treated With Cell Therapy | completed | Phase 1 | 81 | University of PennsylvaniaOTHER | 1 | Sep 23, 2021 | clinicaltrials |
| NCT04841850 | Efficiency And Tolerance Of Hazelnut Oral Immunotherapy Protocol In Hazelnut Allergic Children(ENOIME) | completed | — | 70 | Hospices Civils de LyonOTHER | 1 | Sep 17, 2021 | clinicaltrials |
| NCT05021159 | Assessing the Ontogeny of P-glycoprotein Expression in Blood of Pediatric Leukemic Patients | completed | — | 20 | Tanta UniversityOTHER | 1 | Sep 2, 2021 | clinicaltrials |
| NCT03545659 | Childhood Acute Lymphoblastic Leukaemia: Follow-Up | completed | — | 277 | University of AarhusOTHER | 5 | Sep 1, 2021 | clinicaltrials |
| NCT02559557 | Culturally Adapted Parenting Intervention for Spanish-Speaking Parents in Improving Outcomes of Younger Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia Survivors at Risk for Late Neurocognitive Effects | completed | N/A | 38 | City of Hope Medical CenterOTHER | 1 | Aug 12, 2021 | clinicaltrials |
| NCT01221857 | Pilot Study Evaluating Safety & Efficacy of DCBT: NiCord® & UNM CBU to Patients With Hematological Malignancies | completed | Phase 1 / Phase 2 | 12 | Gamida Cell ltdINDUSTRY | 1 | Aug 3, 2021 | clinicaltrials |
| NCT02133599 | Prediction of Excretion and Toxicity of High Dose Methotrexate in Children and Adolescents With ALL | completed | N/A | 23 | Ann & Robert H Lurie Children's Hospital of ChicagoOTHER | 1 | Aug 2, 2021 | clinicaltrials |
| NCT00171249 | An Extension Study to Determine the Safety and Anti-Leukemic Effects of Imatinib Mesylate in Adult Participants With Ph+ Leukemia | completed | Phase 2 | 293 | Novartis PharmaceuticalsINDUSTRY | 5 | Jul 22, 2021 | clinicaltrials |
| NCT03555955 | A Trial to Evaluate the Potential Impact of Renal Impairment on the Pharmacokinetics and Safety of CPX-351 | completed | Phase 1 | 21 | Jazz PharmaceuticalsINDUSTRY | 2 | Jul 22, 2021 | clinicaltrials |
| NCT03123939 | Phase III B in Acute Lymphoblastic Leukemia | completed | Phase 3 | 69 | Novartis PharmaceuticalsINDUSTRY | 9 | Jul 21, 2021 | clinicaltrials |
| NCT04800848 | Effects of the Face Mask on Physical Fitness in Children(MaskFIT) | completed | — | 165 | University of OviedoOTHER | 1 | Jul 20, 2021 | clinicaltrials |
| NCT04959409 | Topical Analgesia Before Inhalational Anaesthesia | completed | — | 500 | Nottingham University Hospitals NHS TrustOTHER | 1 | Jul 13, 2021 | clinicaltrials |
| NCT02906371 | Study of the Tocilizumab Optimization Timing for CART19 Associated Cytokine Release Syndrome | completed | Phase 1 | 80 | University of PennsylvaniaOTHER | 1 | Jul 2, 2021 | clinicaltrials |
| NCT04082286 | Yttrium-90 Anti CD66 Monoclonal Antibody in Childhood Relapsed/Refractory Leukaemia | completed | Phase 1 | 9 | Great Ormond Street Hospital for Children NHS Foundation TrustOTHER | 1 | Jun 25, 2021 | clinicaltrials |
| NCT01822509 | Ipilimumab or Nivolumab in Treating Patients With Relapsed Hematologic Malignancies After Donor Stem Cell Transplant | completed | Phase 1 | 71 | National Cancer Institute (NCI)NIH | 1 | Jun 24, 2021 | clinicaltrials |
| NCT01643408 | A Study of Erwinaze Administered Intravenously in Patients Who Had an Allergy to Frontline Asparaginase Therapy | completed | Phase 2 | 30 | Jazz PharmaceuticalsINDUSTRY | 2 | Jun 23, 2021 | clinicaltrials |
| NCT00860574 | Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia | completed | Phase 2 | 96 | Fred Hutchinson Cancer CenterOTHER | 1 | Jun 22, 2021 | clinicaltrials |
| NCT01817075 | Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant | completed | Phase 3 | 177 | Children's Oncology GroupNETWORK | 3 | Jun 22, 2021 | clinicaltrials |
| NCT00378534 | Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants | completed | Phase 2 | 116 | National Heart, Lung, and Blood Institute (NHLBI)NIH | 1 | Jun 16, 2021 | clinicaltrials |
| NCT00103285 | Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia | completed | Phase 3 | 5,377 | Children's Oncology GroupNETWORK | 5 | Jun 14, 2021 | clinicaltrials |
Data updated 24 days agoSource updated Apr 15, 2022source: clinicaltrials