Clinical trial · Interventional
Dexamethasone & Ketamine as Adjuvants to Bupivacaine for Incisional Infiltration in Pediatric Abdominal Operations
A Comparative Study Between Dexamethasone and Ketamine as Adjuvants to Bupivacaine for Incisional Infiltration in Pediatric Abdominal Operations
NCT05190952CI-TRIAL-00055959completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to compare the effects of both ketamine and dexamethasone on the duration and magnitude of analgesia when combined with bupivacaine for incisional infiltration in pediatric abdominal operations.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pediatric ALL | Childhood Acute Lymphoblastic Leukemia | ALIAS | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Bupivacaine | Drug | — | UNRESOLVED |
| Dexamethasone | Drug | Dexamethasone | ALIAS |
| Ketamine | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Group 1
- description
- Control Group (Bupivacaine 0.25% 1ml/kg will be injected subcutaneously by the surgeon before wound closure).
- interventionNames
- Drug: Bupivacaine
- type
- ACTIVE_COMPARATOR
- label
- Group 2
- description
- Ketamine Group (In addition to bupivacaine, ketamine 1mg/kg diluted in 10 ml normal saline will be injected subcutaneously by the surgeon before wound closure. Bupivacaine and ketamine will be administered using two separate syringes).
- interventionNames
- Drug: Bupivacaine
- Drug: Ketamine
- type
- ACTIVE_COMPARATOR
- label
- Group 3
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Year
- Maximum age
- 8 Years
Show eligibility criteria text
Inclusion Criteria: * Children of both sexes aged 1-8 years, ASA I-II, undergoing moderate to major abdominal operations. Exclusion Criteria: * History of diabetes, cardiac or neurological disease * Hypersensitivity to any of the drugs used in the study. * Risk of wound complications ( as infected wound, history of wound dehiscence, hypo--albuminaemia) * Multiple incision sites
References
Publications (0)
Data not yet available
No reference posted for this study.