Clinical trial · Interventional
Nalbuphine Versus Ketamine for Prevention of Emergence Agitation After Sevoflurane in Children Undergoing Tonsillectomy
The Effect of Low Dose Nalbuphine or Ketamine in the Prevention of Emergence Agitation After Sevoflurane Anesthesia in Children Undergoing Tonsillectomy With or Without Adenoidectomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The effect of low dose nalbuphine or ketamine in the prevention of emergence agitation after sevoflurane anesthesia in children undergoing tonsillectomy with or without adenoidectomy. This randomized double-blind study was carried out at, Ain shams University Hospitals, from March 2021 to June 2021 on 90 patients after approval of the ethical committee.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pediatric ALL | Childhood Acute Lymphoblastic Leukemia | ALIAS | 0.90 |
| Pediatric Anesthesia | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ketamine | Drug | — | UNRESOLVED |
| Nalbuphine Injection | Drug | — | UNRESOLVED |
| Saline | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Nalbuphine arm
- description
- 0.1 mg /kg nalbuphine was given to 30 patients
- interventionNames
- Drug: Nalbuphine Injection
- type
- ACTIVE_COMPARATOR
- label
- Ketamine arm
- description
- 0.25 mg /kg ketamine was given to 30 patients
- interventionNames
- Drug: Ketamine
- type
- PLACEBO_COMPARATOR
- label
- Saline arm
- description
- an equivalent volume of normal saline was given to 30 patients
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 4 Years
- Maximum age
- 10 Years
Show eligibility criteria text
Inclusion Criteria: Pediatric patients undergoing tonsillectomy with or without adenoidectomy 1. Age 4 - 10 years. 2. Sex: Both sexes 3. Patients with ASA classificaion I and II. Exclusion Criteria: 1. Declining to give written informed consent. 2. History of allergy to the medications used in the study. 3. psychiatric disorder. 4. ASA classification III-V. 5. Fever ,cough , asthma or upper respiratory tract infection . 6. Anticipated difficult airway . 7. Hearing defect . 8. Neurological disorder. 9. Family history of malignant hyperthermia .
References
Publications (0)
Data not yet available