Hematologic Malignancy
Acute Lymphoblastic Leukemia
CI-CAN-00000400ALLExplore in graph →
Hematologic546 active trials12 approved drugs43 evidence items
- NCIt
- C3167
- DOID
- 9952
- MeSH
- D054198
- Other
- 3 more codes
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Hematologic Malignancy
CI-CAN-00000400ALLExplore in graph →
Clinical trials
2,037 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (268)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05137860 | Efficacy of the Use of Bortezomib for the Treatment of Relapsed Leukemia or Positive MRD | unknown | Phase 4 | 56 | Hospital General de MexicoOTHER_GOV | 1 | Jan 18, 2022 | clinicaltrials |
| NCT05133310 | Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia | unknown | Phase 4 | 108 | Hospital General de MexicoOTHER_GOV | 1 | Jan 4, 2022 | clinicaltrials |
| NCT05127135 | Safety and Efficacy of ThisCART7 in Patients With Refractory or Relapsed T Cell Malignancies | unknown | Phase 1 | 30 | Fundamenta Therapeutics, Ltd.INDUSTRY | 1 | Nov 19, 2021 | clinicaltrials |
| NCT04593745 | Intraocular Pressure in Children With Acute Lymphoblastic Leukemia (ALL) Treated With High Dose Steroids(ALL) | unknown | N/A | 100 | Rabin Medical CenterOTHER | 1 | Oct 22, 2021 | clinicaltrials |
| NCT05066958 | Ex-vivo Primed Memory Donor Lymphocyte Infusion to Boost Anti-viral Immunity After T-cell Depleted HSCT | unknown | Phase 1 / Phase 2 | 20 | Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyOTHER | 1 | Oct 4, 2021 | clinicaltrials |
| NCT05024357 | A Study of TKI Maintenance Therapy Following Allo-HSCT in Newly Diagnosed Ph+ Adult ALL | unknown | N/A | 80 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Oct 1, 2021 | clinicaltrials |
| NCT05026229 | A Study of Dasatinib Plus Reduced Intensive Consolidation Chemotherapy in Ph+ Adult ALL | unknown | N/A | 60 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Oct 1, 2021 | clinicaltrials |
| NCT03887156 | Evaluation of a Donor Testing Kit for the Prediction of AGVHD in Patient Receiving a Peripheral Blood Stem Cell Allograft(Predictor2) | unknown | Phase 2 / Phase 3 | 227 | Assistance Publique - Hôpitaux de ParisOTHER | 3 | Sep 28, 2021 | clinicaltrials |
| NCT05059847 | Impact of Cross-training on Induction Treatment Response in Acute Lymphoblastic Leukemia Adults | unknown | N/A | 114 | Hospital General de MexicoOTHER_GOV | 1 | Sep 28, 2021 | clinicaltrials |
| NCT05054465 | A Phase 1b-2 Trial to Assess Venetoclax and Navitoclax Consolidation and Post-transplant Maintenance in High-risk Patients With T-ALL(ITALLI001) | unknown | Phase 1 / Phase 2 | 48 | Israeli Medical AssociationOTHER | 1 | Sep 23, 2021 | clinicaltrials |
| NCT04826146 | Pediatric Validation of CONOX Monitor During Surgery | unknown | — | 65 | Patricio Gonzalez PizarroOTHER | 1 | Sep 9, 2021 | clinicaltrials |
| NCT05038696 | ALaCART-B: Acute Leukemia and Chimeric Antigen Receptor-T Cell Therapy for B-lymphoblastic Leukemia.(ALaCART) | unknown | Phase 1 | 40 | National University Hospital, SingaporeOTHER | 1 | Sep 9, 2021 | clinicaltrials |
| NCT03798509 | Human CD19 Targeted T Cells Injection Therapy for Relapsed and Refractory CD19-positive Leukemia | unknown | Phase 1 | 18 | Hrain Biotechnology Co., Ltd.INDUSTRY | 1 | Aug 31, 2021 | clinicaltrials |
| NCT04735211 | Chronic Postsurgical Pediatric Pain. Evaluation Risk Factors to Develop Chronic Postsurgical Pain in Children and Adolescents Undergoing Surgery in a First Level Hospital | unknown | — | 260 | Guillermo Ceniza BordalloOTHER | 1 | Aug 13, 2021 | clinicaltrials |
| NCT04960761 | The Effectiveness of the Training Given With Audio and Picture Book Before the Surgery | unknown | N/A | 70 | Saglik Bilimleri UniversitesiOTHER | 1 | Aug 12, 2021 | clinicaltrials |
| NCT04977895 | Monitoring Minimal Residual Disease（MRD）in Pediatric B-acute Lymphoblastic Leukemia | unknown | — | 255 | Sun Yat-sen UniversityOTHER | 1 | Jul 27, 2021 | clinicaltrials |
| NCT04934774 | Non-gene Edited Anti-CD7 CAR T Cells for Relapsed/Refractory T Cell Malignances | unknown | Phase 1 | 20 | iCell Gene TherapeuticsINDUSTRY | 1 | Jun 22, 2021 | clinicaltrials |
| NCT04888442 | Phase I Study of pCAR-19B in the Treatment of Adult CD19-positive Relapsed/Refractory B-ALL | unknown | Phase 1 | 18 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | May 17, 2021 | clinicaltrials |
| NCT04289220 | Anti-CD19 CAR in PiggyBac Transposon-Engineered T Cells for Relapsed/Refractory B-cell Lymphoma or B-cell Acute Lymphoblastic Leukemia | unknown | Phase 1 | 10 | Yan'an Affiliated Hospital of Kunming Medical UniversityOTHER | 1 | May 13, 2021 | clinicaltrials |
| NCT04334993 | Pediatric-type Therapy With Pre-transplant Blinatumomab for HR Patients - Phase II Study | unknown | Phase 2 | 110 | Israeli Medical AssociationOTHER | 1 | May 7, 2021 | clinicaltrials |
| NCT04796675 | Cord Blood Derived Anti-CD19 CAR-Engineered NK Cells for B Lymphoid Malignancies | unknown | Phase 1 | 27 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Apr 8, 2021 | clinicaltrials |
| NCT04814004 | Clinical Study of CAR-iNKT Cells in the Treatment of Relapsed/Refractory/High-risk B-cell Tumors | unknown | Phase 1 | 20 | Kai Lin Xu; Jun Nian ZhengOTHER | 1 | Mar 29, 2021 | clinicaltrials |
| NCT04653493 | CD19 Targeted CAR T Cell Therapy in Patients With Relapsed/ Refractory B Cell Acute Lymphoblastic Leukaemia (ALL) | unknown | Phase 1 | 22 | Sabz BiomedicalsINDUSTRY | 1 | Mar 19, 2021 | clinicaltrials |
| NCT04796688 | Universal Chimeric Antigen Receptor-modified AT19 Cells for CD19+ Relapsed/Refractory Hematological Malignancies | unknown | Phase 1 | 27 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Mar 15, 2021 | clinicaltrials |
| NCT04792593 | Senl-h19 CAR-T Cell Injection in the Treatment of Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia | unknown | N/A | 15 | Hebei Senlang Biotechnology Inc., Ltd.INDUSTRY | 1 | Mar 11, 2021 | clinicaltrials |
| NCT04785833 | CD7 CAR-T in the Treatment of CD7 Positive Refractory Relapsed Acute Leukemia | unknown | N/A | 20 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 1 | Mar 8, 2021 | clinicaltrials |
| NCT04594135 | Anti-CD5 CAR T Cells for Relapsed/Refractory T Cell Malignancies(CD5CAR-T) | unknown | Phase 1 | 20 | iCell Gene TherapeuticsINDUSTRY | 1 | Mar 2, 2021 | clinicaltrials |
| NCT04755478 | LUS to Assess Lung Injury After Lung Lobectomy(OPEN THORUS) | unknown | — | 30 | Hospital General Universitario de ValenciaOTHER | 1 | Feb 16, 2021 | clinicaltrials |
| NCT02186860 | Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy in Treating Patients With Acute Lymphoblastic Leukemia | unknown | Phase 1 | 5 | Affiliated Hospital to Academy of Military Medical SciencesOTHER | 1 | Feb 10, 2021 | clinicaltrials |
| NCT04670731 | Ventricular Remodelling and Metabolomics in Pediatric Cardiomyopathies (PROGRESS-OMICS)(PRO-OMICS) | unknown | — | 100 | Bambino Gesù Hospital and Research InstituteOTHER | 1 | Feb 10, 2021 | clinicaltrials |
| NCT04747093 | Induced-T Cell Like NK Cells for B Cell Malignancies | unknown | Phase 1 / Phase 2 | 12 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Feb 10, 2021 | clinicaltrials |
| NCT04740203 | Sequential CD19 and CD22 CAR-T Therapy for Newly Diagnosed Ph- B-ALL | unknown | Phase 1 / Phase 2 | 50 | Zhejiang UniversityOTHER | 1 | Feb 5, 2021 | clinicaltrials |
| NCT03156101 | A Clinical Study Evaluating the Safety and Efficacy of BinD19 Treatment in R/R ALL and Lymphoma Subjects | unknown | Phase 1 / Phase 2 | 24 | Shenzhen BinDeBio Ltd.INDUSTRY | 1 | Feb 4, 2021 | clinicaltrials |
| NCT03265106 | A Clinical Study Evaluating the Safety and Efficacy of BinD19 Treatment in Childhood R/R ALL and Lymphoma Subjects | unknown | Phase 1 / Phase 2 | 20 | Shenzhen BinDeBio Ltd.INDUSTRY | 1 | Feb 4, 2021 | clinicaltrials |
| NCT04204161 | A Clinical Study of CAR-T Cells Treatment for Children With CD19+/CD22+ R/R ALL and Lymphoma | unknown | Phase 1 | 30 | Shenzhen BinDeBio Ltd.INDUSTRY | 1 | Feb 4, 2021 | clinicaltrials |
| NCT04723901 | Dual Target CAR-T Cells in B-cell Acute Lymphoblastic Leukemia(CAR-T) | unknown | Phase 1 / Phase 2 | 20 | Shenzhen University General HospitalOTHER | 1 | Jan 26, 2021 | clinicaltrials |
| NCT04723342 | Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2019 Pilot | unknown | N/A | 180 | Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyOTHER | 1 | Jan 25, 2021 | clinicaltrials |
| NCT03840317 | Senl_1904A and Senl_1904B Chimeric Antigen Receptor （CAR） T-Cell in the Treatment of r/ r Acute B Lymphocytic Leukemia | unknown | Phase 1 | 20 | Hebei Senlang Biotechnology Inc., Ltd.INDUSTRY | 1 | Jan 20, 2021 | clinicaltrials |
| NCT03889483 | Neurophysiological Measurements Using the NeuroCatch™ Platform in Pediatric Concussion | unknown | N/A | 105 | Dr. Michael EsserOTHER | 1 | Jan 13, 2021 | clinicaltrials |
| NCT04688983 | Study in Adult Ph-positive ALL(EWALL-Ph-03) | unknown | Phase 2 | 180 | Cardiff UniversityOTHER | 0 | Dec 30, 2020 | clinicaltrials |
| NCT04679506 | the Efficacy and Safety of CLAE in R/R T-ALL/LBL | unknown | — | 50 | Peking University Third HospitalOTHER | 0 | Dec 22, 2020 | clinicaltrials |
| NCT04677231 | Evaluation of Long-term Health Status and Quality of Life in Adult Survivors With Philadelphia-negative Acute Lymphoblastic Leukemia/Lymphoma Treated With an Intensive Pediatric or Pediatric-inspired Protocol(EQUAALL01) | unknown | — | 300 | Assistance Publique - Hôpitaux de ParisOTHER | 0 | Dec 21, 2020 | clinicaltrials |
| NCT04100070 | Intensive Versus Standard One Year Monitoring on Glycaemic Control After Initiating CSII in Children With DT1. DEEP Study(DEEP) | unknown | N/A | 320 | ISIS Diabete ServiceOTHER | 1 | Dec 4, 2020 | clinicaltrials |
| NCT04117854 | Spinal Cord Injury in the Pediatric Population - an International Multicenter Study(SINpedSCI) | unknown | — | 30 | Sunnaas Rehabilitation HospitalOTHER | 8 | Dec 2, 2020 | clinicaltrials |
| NCT03981510 | Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation | unknown | N/A | 80 | University of AarhusOTHER | 1 | Nov 25, 2020 | clinicaltrials |
| NCT04640064 | Hb A1C Pre and Post Confinement in Latin American Children With Type 1 Diabetes: Dulce Study Group | unknown | — | 500 | Hospital General PuyoOTHER_GOV | 1 | Nov 23, 2020 | clinicaltrials |
| NCT04000698 | Personalized Targeted Preparative Regimen Before T-depleted Allogeneic HSCT in Children With Chemoresistent Acute Leukemias | unknown | Phase 3 | 25 | Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyOTHER | 1 | Nov 20, 2020 | clinicaltrials |
| NCT04516551 | Anti-CD19 Allo-CAR-T Cells for Relapsed B Cell Malignancies After HSCT | unknown | Phase 1 | 18 | Xinqiao Hospital of ChongqingOTHER | 1 | Nov 17, 2020 | clinicaltrials |
| NCT04626726 | Adult B-ALL Treated by CART Cell Bridging Allogeneic Hematopoietic Stem Cell Transplantation | unknown | Early Phase 1 | 50 | Hebei Senlang Biotechnology Inc., Ltd.INDUSTRY | 1 | Nov 13, 2020 | clinicaltrials |
| NCT04626765 | CAR-T for Children With Relapsed and Refractory Acute Lymphoblastic Leukemia | unknown | Early Phase 1 | 50 | Hebei Senlang Biotechnology Inc., Ltd.INDUSTRY | 1 | Nov 13, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Jan 18, 2022source: clinicaltrials