Clinical trial · Observational
LUS to Assess Lung Injury After Lung Lobectomy
Ultrasound Assessment of Aeration Changes After Lung Lobectomy: a Pilot Study
NCT04755478CI-TRIAL-00050074OPEN THORUSunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to assess whether lung ultrasound is able to detect lung injury after lung resection surgery.
Conditions
Conditions (9)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adult ALL | Adult Acute Lymphoblastic Leukemia | ALIAS | 0.90 |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Lung Inflammation | — | UNRESOLVED | — |
| Lung Injury | — | UNRESOLVED | — |
| Lung Ischemia/Hypoxia | — | UNRESOLVED | — |
| Lung Neoplasm | Lung Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Postoperative Complications | — | UNRESOLVED | — |
| Postoperative Respiratory Complication | — | UNRESOLVED | — |
| Thoracic | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Thoracotomy | Procedure | — | UNRESOLVED |
| VATS | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Lung lobectomy via open thoracotomy
- description
- participants scheduled for lung lobectomy via open thoracotomy
- interventionNames
- Procedure: Thoracotomy
- label
- Lung lobectomy via VATS
- description
- participants scheduled for lung lobectomy via video-assisted thoracoscopic surgery
- interventionNames
- Procedure: VATS
Primary outcomes (1)
- measure
- Change in mLUSS after lung resection.
- timeFrame
- preoperative vs immediate postoperative period vs 24 hours after surgery.
- description
- The modified lung ultrasound score (mLUSS) ranges 0-36; the higher the score, the less aeration (worse).
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age \> 18 * ASA I-III * Non-small cell lung neoplasm * Elective lung lobectomy * Under one-lung ventilation Exclusion Criteria: * Pregnancy * Respiratory tract infection the previous month * Diagnosed pulmonary fibrosis * Predicted FEV \< 40% * Surgery that includes resection of the thoracic wall or the diaphragm * Neoplasm metastasis * Obesity class II or more (BMI ≥ 35 kg/m\^2) * Risk of malnutrition CONUT \> 1 * Hemoglobin \< 10 g/dl * Chronic kidney failure: glomerular filtration \< 60 ml/min/m\^2, nephrectomy, kidney transplantation * Treatment with corticosteroids or immunosuppressive agents 3 months before surgery * Transfusion of blood products during the previous 10 days * Heart failure (New York Heart Association Functional Class 3 or 4) during the week before surgery. * Heart valve diseases over stage B of the American College of Cardiology/American * Heart Association Task Force on Practice Guidelines 2014 * Diastolic dysfunction
References
Publications (0)
Data not yet available
No reference posted for this study.