Clinical trial · Interventional
Intraocular Pressure in Children With Acute Lymphoblastic Leukemia (ALL) Treated With High Dose Steroids
Intraocular Pressure in Children With ALL Treated With High Dose Steroids
NCT04593745CI-TRIAL-00054615ALLunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Childhood ALL patients are treated with high dose steroids. The study will follow the intraocular pressure of children treated in according to an AIEOP-BFM protocol, during the induction phase that will be compared to the pressure before treatment. Potential risk factors for developing elevated intraocular pressure will be estimated.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| ALL, Childhood | Childhood Acute Lymphoblastic Leukemia | ALIAS | 0.90 |
| Steroid-Induced Glaucoma | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intraocular pressure measurment | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- ALL AIEOP-BFM induction
- description
- Intraocular pressure messured in children treated with steroids
- interventionNames
- Device: Intraocular pressure measurment
Primary outcomes (2)
- measure
- intra-ocular pressure (IOP)
- timeFrame
- 15 days of steroid treatment
- description
- Elevated IOP will be defined as pressure \>21 mmHg; The risk of developing elevated IOP will be correlated with potential risk factors (T ALL vs. B ALL; WBC at diagnosis; initial IOP at diagnosis etc.)
- measure
- intra-ocular pressure (IOP)
- timeFrame
- 1 month of steroid treatment
- description
- Elevated IOP will be defined as pressure \>21 mmHg; The risk of developing elevated IOP will be correlated with potential risk factors (T ALL vs. B ALL; WBC at diagnosis; initial IOP at diagnosis etc.)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Month
- Maximum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * ALL diagnosis * treated with an AIEOP-BFM protocol (including steroids) Exclusion Criteria: \* Any prior eye condition that can affect intra ocular pressure or its measurement
References
Publications (0)
Data not yet available
No reference posted for this study.