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Genomics
2 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
47 cases with simple somatic mutation data · 47 cases total · 2026-01-12 · mapped to Pancreatic Acinar Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | SMAD4 | Ssm | 8 | 47 | 17% | cbioportal |
| 2 | AXIN1 | Ssm | 6 | 47 | 12.8% | cbioportal |
| 3 | CTNNB1 | Ssm | 6 | 47 | 12.8% | cbioportal |
| 6 | RB1 | Ssm | 5 | 47 | 10.6% | cbioportal |
| 5 | PRKAR1A | Ssm | 5 | 47 | 10.6% | cbioportal |
| 4 | NF1 | Ssm | 5 | 47 | 10.6% | cbioportal |
| 8 | PBRM1 | Ssm | 4 | 47 | 8.5% | cbioportal |
| 7 | CREBBP |
Data updated 21 days agoSource updated 2026-01-12
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 4 |
| 47 |
| 8.5% |
| cbioportal |
| 9 | PTEN | Ssm | 4 | 47 | 8.5% | cbioportal |
| 155 | SLFN11 | Ssm | 1 | 13 | 7.7% | cbioportal |
| 93 | GNB1 | Ssm | 1 | 13 | 7.7% | cbioportal |
| 172 | ZNRF3 | Ssm | 1 | 13 | 7.7% | cbioportal |
| 154 | SETDB1 | Ssm | 1 | 13 | 7.7% | cbioportal |
| 19 | MGA | Ssm | 3 | 46 | 6.5% | cbioportal |
| 16 | IKBKE | Ssm | 3 | 47 | 6.4% | cbioportal |
| 15 | CDKN2A | Ssm | 3 | 47 | 6.4% | cbioportal |
| 20 | NRAS | Ssm | 3 | 47 | 6.4% | cbioportal |
| 13 | BRAF | Ssm | 3 | 47 | 6.4% | cbioportal |
| 14 | BRCA2 | Ssm | 3 | 47 | 6.4% | cbioportal |
| 21 | PIK3CG | Ssm | 3 | 47 | 6.4% | cbioportal |
| 22 | POLE | Ssm | 3 | 47 | 6.4% | cbioportal |
| 10 | ARID1A | Ssm | 3 | 47 | 6.4% | cbioportal |
| 23 | RARA | Ssm | 3 | 47 | 6.4% | cbioportal |
| 11 | ASXL1 | Ssm | 3 | 47 | 6.4% | cbioportal |
| 17 | KMT2D | Ssm | 3 | 47 | 6.4% | cbioportal |
| 12 | ATM | Ssm | 3 | 47 | 6.4% | cbioportal |
| 24 | SETD2 | Ssm | 3 | 47 | 6.4% | cbioportal |
| 18 | MEN1 | Ssm | 3 | 47 | 6.4% | cbioportal |
| 25 | TP53 | Ssm | 3 | 47 | 6.4% | cbioportal |
| 26 | TSC2 | Ssm | 3 | 47 | 6.4% | cbioportal |