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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
380 stopped studies mapped to Malignant Uterine Neoplasm and descendants · 86% state a reason
Over the 380 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01251354 | Study of BN83495 in Post-menopausal Women With Endometrial Cancer Post-chemotherapy | Phase 2 | terminated | Dec 1, 2010 | Ipsen | The futility analysis of study NCT00910091 in patients with endometrial cancer shows that the… | Efficacy / futility |
| NCT00257829 | Improving Tumor Oxygenation in Cervical Cancer | Phase 2 | withdrawn | Nov 23, 2005 | University of California, Irvine | This study was closed due to lack of funding. | Funding |
| NCT02868892 | A Study of Pemetrexed in Recurrent Cervical Adenocarcinomas | Phase 2 | terminated | Aug 16, 2016 | Western Regional Medical Center | departure of PI from institution and poor population for study participation | Other (stated, no rule matched) |
| NCT02589366 | Lymphoseek as Lymphoid Tissue Targeting Agent in Patients With Cancer of the Endometrium | Phase 1 | terminated | Oct 28, 2015 | University of California, San Diego | not stated | Not stated |
| NCT03220009 | Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in… | Phase 2 | withdrawn | Jul 18, 2017 | National Cancer Institute (NCI) | The study was never approved by CTEP neither was it ever activated | Other (stated, no rule matched) |
| NCT00003821 | Aminopterin in Treating Patients With Recurrent or Refractory Endometrial Cancer | Phase 2 | withdrawn | Aug 4, 2004 | Genzyme, a Sanofi Company | not stated | Not stated |
| NCT00730886 | ExAblate Treatment of Uterine Fibroids for Fertility Enhancement | N/A | terminated | Aug 8, 2008 | InSightec | not stated | Not stated |
| NCT00084890 | Docetaxel and Carboplatin in Treating Patients With Recurrent Stage IVB Squamous Cell… | Phase 1 | terminated | Jun 11, 2004 | Wake Forest University Health Sciences | slow accrual | Enrollment / accrual |
| NCT01197664 | Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer… | Phase 1 | terminated | Sep 9, 2010 | Wake Forest University Health Sciences | Study terminated due to funding issues | Funding |
| NCT01328067 | Study to Evaluate the Safety and Effectiveness of MRgFUS Compared With Myomectomy for the… | N/A | withdrawn | Apr 4, 2011 | InSightec | not stated | Not stated |
| NCT00899093 | YKL-40 in Serum Samples From Patients With Newly Diagnosed Stage III-IV Ovarian… | — | terminated | May 12, 2009 | Gynecologic Oncology Group | not stated | Not stated |
| NCT01275664 | Granisetron, Aprepitant, and Dexamethasone in Preventing Nausea and Vomiting in Patients… | N/A | terminated | Jan 12, 2011 | Gynecologic Oncology Group | Study terminated due to no patient population available | Other (stated, no rule matched) |
| NCT02412124 | Peer-to-Peer Support Program in Improving Quality of Life Outcomes in Patients With… | N/A | terminated | Apr 8, 2015 | City of Hope Medical Center | Feasibility issues | Other (stated, no rule matched) |
| NCT02765698 | Efficacy of PET/MRI in Detecting Metastatic Disease in Endometrial Cancer | — | terminated | May 9, 2016 | Mayo Clinic | not stated | Not stated |
| NCT02110953 | Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal… | Phase 1 | terminated | Apr 10, 2014 | Fox Chase Cancer Center | IRB study closure by investigator due to low enrollment | Investigator |
| NCT00004261 | EF5 Prior to Surgery or Biopsy in Patients With Breast, Prostate, or Cervical Cancer or… | Phase 1 | terminated | Dec 11, 2003 | University Health Network, Toronto | Lack of patient accrual | Enrollment / accrual |
| NCT00588263 | Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish… | — | withdrawn | Jan 8, 2008 | Memorial Sloan Kettering Cancer Center | Data from MSK-IMPACT is sufficient for relevant analyses going forward | Other (stated, no rule matched) |
| NCT01934179 | Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal… | — | terminated | Sep 4, 2013 | Fox Chase Cancer Center | Low Accrual Rate | Enrollment / accrual |
| NCT02736435 | Treatment of Uterine Fibroids With Magnetic Resonance Guided High Intensity Focused… | Phase 3 | withdrawn | Apr 13, 2016 | Thunder Bay Regional Health Research Institute | Lengthy delays and inadequate support to proceed. | Other (stated, no rule matched) |
| NCT00375804 | Racial Disparity in Endometrial Cancer | — | terminated | Sep 13, 2006 | University of Louisville | Funding and logistical difficuties resulted in the withdrawl of the study. | Funding |
| NCT01575444 | Cervical Cancer Screening Project Part C | — | terminated | Apr 11, 2012 | University of Minnesota | Investigator left University No results are possible | Investigator |
| NCT00428194 | Erlotinib, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB-Stage IVA… | Phase 1 | withdrawn | Jan 29, 2007 | Masonic Cancer Center, University of Minnesota | Withdrawn due to lack of accrual | Enrollment / accrual |
| NCT00278434 | Zoledronate in Treating Patients With Cervical Intraepithelial Neoplasia 2/3 or 3 | Phase 1 | terminated | Jan 18, 2006 | University of California, San Francisco | Accrual was insufficient to meet study endpoints | Enrollment / accrual |
| NCT00070317 | Lymph Node Mapping and Sentinel Lymph Node Identification in Patients With Stage IB1… | N/A | terminated | Oct 7, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT03007771 | Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild… | Phase 1 | withdrawn | Jan 2, 2017 | Washington University School of Medicine | Decision was made to not go forward with the study | Other (stated, no rule matched) |
| NCT00003525 | Antineoplaston Therapy in Treating Patients With Stage IV Cancer of the Cervix and/or… | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | slow accrual | Enrollment / accrual |
| NCT00600210 | Neoadjuvant Bevacizumab and Carboplatin Followed by Concurrent Bevacizumab, Carboplatin… | Phase 2 | withdrawn | Jan 24, 2008 | Leo W. Jenkins Cancer Center | low patient accrual | Enrollment / accrual |
| NCT01842789 | Post Market Evaluation of Acessa With TAG(TAG) | N/A | terminated | Apr 30, 2013 | Acessa Health, Inc. | Results to date adequately demonstrated user preference and recovery time. Time to target (Part II)… | Other (stated, no rule matched) |
| NCT00004221 | Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients… | Phase 2 | terminated | Aug 25, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00900081 | Cyclooxygenase-2 Expression in Tissue Samples From Patients With a Normal Cervix,… | — | withdrawn | May 12, 2009 | Wake Forest University Health Sciences | no accrual, PI left institution | Investigator |
| NCT01641497 | Phase III Study Comparing 3D Conformal Radiotherapy and Conformal Radiotherapy IMRT to…(TOMOGYN) | N/A | terminated | Jul 16, 2012 | Centre Oscar Lambret | Recruitment difficulties | Enrollment / accrual |
| NCT01754519 | Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer… | Phase 2 | terminated | Dec 21, 2012 | Roswell Park Cancer Institute | IDE not submitted | Other (stated, no rule matched) |
| NCT01176500 | A Pilot, Open-label Study of 18F-Fluciclatide PET/CT Imaging in the Evaluation of… | Phase 1 / Phase 2 | withdrawn | Aug 6, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01184053 | Trisenox® in Women With Metastatic Endometrial Cancer(NRR) | Phase 2 | terminated | Aug 18, 2010 | UNC Lineberger Comprehensive Cancer Center | Accrual was very low. No subject had been enrolled in a year. | Enrollment / accrual |
| NCT01461772 | Efficacy and Safety Study of Concurrent Chemoradiation Therapy to Treat Locally Advanced… | Phase 3 | terminated | Oct 28, 2011 | Asan Medical Center | Because of very slow rate of enrollement | Enrollment / accrual |
| NCT02338141 | Accuracy of Portable Colposcopy and HPV Genotypes Among HIV+ Women | N/A | terminated | Jan 14, 2015 | Duke University | Funding unavailable to perform study. | Funding |
| NCT02633254 | Targeted Vessel Ablation of Type 3 Uterine Fibroids With Magnetic Resonance Guided High… | N/A | terminated | Dec 17, 2015 | UMC Utrecht | not stated | Not stated |
| NCT01504308 | Sonalleve Fibroid Ablation Pivotal Clinical Trial for MR-HIFU of Uterine Fibroids(SOFIA) | Phase 2 / Phase 3 | terminated | Jan 5, 2012 | Philips Healthcare | It was not possible to enroll patients into the study in a realistic timeframe. | Enrollment / accrual |
| NCT00883116 | A Study of Ixabepilone as Second-line Therapy for Locally Advanced, Recurrent, or…(IXAMPLE2) | Phase 3 | terminated | Apr 17, 2009 | R-Pharm | Interim analysis results showed that ixabepilone did not improve survival compared with control… | Efficacy / futility |
| NCT00629577 | Gene Expression Profiling of Cervical Cancer Progression in Biopsies and Tissue Samples(SAGE) | Phase 1 | terminated | Mar 6, 2008 | British Columbia Cancer Agency | no funding | Funding |
| NCT00584909 | A Phase II Study of Paclitaxel and Carboplatin in Patients With an Elevated-Risk Cancer… | Phase 2 | terminated | Jan 2, 2008 | University of Alabama at Birmingham | low accrual | Enrollment / accrual |
| NCT01971060 | a Study to Evaluate Adhesion Risk in Fertility Patients' Status Post Laparoscopic…(VLocmyo) | N/A | withdrawn | Oct 28, 2013 | The Advanced Gynecologic Surgery Institute | lack of funding | Funding |
| NCT00452920 | Docetaxel and Radiation Therapy in Treating Patients With Stage II, Stage III, or Stage… | Phase 1 / Phase 2 | withdrawn | Mar 28, 2007 | University of Miami | not stated | Not stated |
| NCT01061606 | Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the Uterus | Phase 2 | terminated | Feb 3, 2010 | National Cancer Institute (NCI) | Poor accrual | Enrollment / accrual |
| NCT02042495 | Endometrial Cancer Biomarker Changes Following Exposure to Metformin | Phase 2 | withdrawn | Jan 23, 2014 | Jewish General Hospital | Did not obtain Health Canda approval for drug use in reasonable time and moved onward to new trial | Other (stated, no rule matched) |
| NCT00590967 | A Phase II Study of Extended Field IMRT External Beam Irradiation and Intracavitary… | Phase 2 | terminated | Jan 11, 2008 | Washington University School of Medicine | Due to low accrual | Enrollment / accrual |
| NCT02348398 | Phase II Study of Pazopanib and Topotecan in Cervical Cancer | Phase 2 | withdrawn | Jan 28, 2015 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT01555073 | Preemptive Analgesia Following Uterine Artery Embolization | Phase 4 | terminated | Mar 15, 2012 | Northwestern University | Subjects did not meet inclusion criteria | Other (stated, no rule matched) |
| NCT00671606 | Hysteroscopic Lymphatic Mapping for Endometrial Cancer | Phase 2 | terminated | May 5, 2008 | M.D. Anderson Cancer Center | Slow accrual. | Enrollment / accrual |
| NCT00529464 | Spectroscopy Versus Standard Care in Cervical Cancer Patients | Phase 3 | terminated | Sep 14, 2007 | M.D. Anderson Cancer Center | Two participants enrolled, both inevaluable. | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Jan 14, 2019source: clinicaltrials