Clinical trial · Interventional
Gene Expression Profiling of Cervical Cancer Progression in Biopsies and Tissue Samples
Ex Vivo Gene Expression Profiling of Cervical Cancer Progression in Biopsies And Tissue Samples From Patients With Cervical Lesions
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): no funding
Summary
Brief summary (as posted)
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research trial is studying gene expression profiling of cervical cancer progression in biopsies and tissue samples from patients with cervical lesions.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
| Precancerous Condition | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| biopsy | Procedure | — | UNRESOLVED |
| colposcopy | Procedure | — | UNRESOLVED |
| flow cytometry | Other | — | UNRESOLVED |
| microarray analysis | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (4)
- measure
- Classification of cervical cancer progression at a molecular level using gene expression profiling
- measure
- Gene expression changes by microarray
- measure
- Set of genes that classify the various grades of cervical cancer/dysplasia
- measure
- Comparison of the expression profiles of clinical data to determine how accurately cell lines model the in vivo environment
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 19 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Clinically suspicious malignant or premalignant cervical lesion Criteria Inclusion criteria: * Included subjects will be ≥18 years old. * Included subjects will not be pregnant. * Included subjects will have a negative urine pregnancy test. * Included subjects will be scheduled for colposcopy and/or LEEP treatment at the VGH Women's Clinic. * Included subjects will indicate understanding of the study. * Included subjects will provide informed consent to participate. Exclusion criteria: * Individuals \<18 years old will be excluded. * Pregnant individuals will be excluded. * Individuals that have had an operation to remove their cervix will be excluded.
References
Publications (0)
Data not yet available