Loading clinical trials…
Loading clinical trials…
Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
1,672 stopped studies mapped to Malignant Reproductive System Neoplasm and descendants · 89% state a reason
Over the 1,672 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01561482 | Study of Metformin With Simvastatin for Men With Prostate Carcinoma | Phase 2 | withdrawn | Mar 23, 2012 | Nicholas Mitsiades | Study closed due to slow/low enrollment; no subjects were enrolled. | Enrollment / accrual |
| NCT00809458 | Biomarker Study of Neoadjuvant Vitamin E in Patients With Locally Treatable Prostate… | Phase 3 | terminated | Dec 17, 2008 | New Mexico Cancer Research Alliance | Low rate of accrual. | Enrollment / accrual |
| NCT00233727 | Screen and Treat for Cervical Cancer Prevention(SAT) | Phase 3 | terminated | Oct 6, 2005 | Columbia University | PI left University | Investigator |
| NCT01808534 | Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors | Phase 2 | terminated | Mar 11, 2013 | Indiana University | Due to Low Accrual | Enrollment / accrual |
| NCT01175772 | Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment… | Phase 2 | terminated | Aug 5, 2010 | HaEmek Medical Center, Israel | Due to change in the national policy of medications | Other (stated, no rule matched) |
| NCT00365443 | Broad Spectrum HPV Vaccine Tolerability, Immunogenicity, and Efficacy Study (V502-003) | Phase 2 | withdrawn | Aug 17, 2006 | Merck Sharp & Dohme LLC | not stated | Not stated |
| NCT00323726 | Trends in Incidence and Survivals for Ovarian Germ Cell Tumors: A 27-Year… | — | withdrawn | May 9, 2006 | New Mexico Cancer Research Alliance | The study was limited to IRB Exempt chart review; not an applicable trial. | Other (stated, no rule matched) |
| NCT00581113 | Neural Stem Cell Preserving Brain Radiation Therapy & Stereotactic Radiosurgery in… | Phase 3 | terminated | Dec 27, 2007 | Virginia Commonwealth University | New research priorities | Other (stated, no rule matched) |
| NCT01705652 | Study to Assess the Activity of Nexrutine® in Prostate Cancer Patients(Nexrutine) | Phase 2 | terminated | Oct 12, 2012 | The University of Texas Health Science Center at San Antonio | loss of funding | Funding |
| NCT01880996 | Tai-chi / Qi-gong in Patients With Patients With Gynecological Malignancies | Phase 1 / Phase 2 | withdrawn | Jun 19, 2013 | Sheba Medical Center | The deparment failed to detect patients that were willing to participate in this study | Other (stated, no rule matched) |
| NCT00921258 | Active Control of Prostatic Cancer With Criteria of Latence(SURACAP) | — | terminated | Jun 16, 2009 | Clinique Mutualiste Chirurgicale de la Loire | Financial problem (not enough budget to continue the study) | Funding |
| NCT01242748 | A Degarelix Trial in Patients With Prostate Cancer | Phase 3 | terminated | Nov 17, 2010 | Ferring Pharmaceuticals | Inadequate recruitment resulting in a too low patient number for collection of long term efficacy… | Efficacy / futility |
| NCT01520441 | BOTOX in Men With Prostate Cancer With Lower Urinary Tract Symptoms(LUTS)/Benign… | Early Phase 1 | withdrawn | Jan 30, 2012 | The University of Texas Health Science Center, Houston | not stated | Not stated |
| NCT02424513 | A Study of Positron Emission Tomography (PET) With [89]Zr-Df-IAb2M in Patients With… | Phase 2 | withdrawn | Apr 23, 2015 | ImaginAb, Inc. | Clinical trial was postponed as a result of restructured business priorities. | Sponsor / business decision |
| NCT00053235 | Research Study in Patients With Advanced Ovarian Epithelial Cancer | — | withdrawn | Jan 28, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00118066 | Calcitriol in Preventing Prostate Cancer in Patients With Prostatic Intraepithelial… | Phase 2 | terminated | Jul 11, 2005 | Rutgers, The State University of New Jersey | Slow accruaL, lack of scientific progress | Enrollment / accrual |
| NCT00824928 | Salvage Cryotherapy in Recurrent Prostate Cancer(SCORE) | — | terminated | Jan 19, 2009 | University of Colorado, Denver | Study was ended due to low enrollment | Enrollment / accrual |
| NCT01200797 | SJG-136 in Treating Patients With Epithelial Ovarian, Primary Peritoneal, or Fallopian… | Phase 2 | terminated | Sep 14, 2010 | National Cancer Institute (NCI) | Slow accrual was the reason for study termination. | Enrollment / accrual |
| NCT01198535 | Phase I Study of Cetuximab With RO4929097 in Metastatic Colorectal Cancer | Phase 1 | terminated | Sep 10, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01401829 | Psychosocial Benefits of Exercise in Endometrial Cancer Survivors | Phase 1 | terminated | Jul 25, 2011 | University of Alabama at Birmingham | Terminated due to lack of funding required to continue the study. | Funding |
| NCT01769911 | Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With… | N/A | withdrawn | Jan 17, 2013 | Fred Hutchinson Cancer Center | not stated | Not stated |
| NCT02235324 | Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in… | Phase 2 | withdrawn | Sep 9, 2014 | University of Southern California | Lack of funding | Funding |
| NCT00176293 | Randomized Phase II Trial of Doxil With or Without Dexamethasone for Metastatic Hormone… | Phase 2 | terminated | Sep 15, 2005 | University of Kentucky | Slow accrual | Enrollment / accrual |
| NCT02420587 | AMG 208 Tumor Microenvironment in Metastatic Castration Resistant Prostate Cancer (mCRPC) | Phase 2 | withdrawn | Apr 20, 2015 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00003880 | Paclitaxel Plus Carboplatin With or Without SCH-58500 in Treating Patients With Newly… | Phase 2 / Phase 3 | terminated | Apr 23, 2004 | Merck Sharp & Dohme LLC | not stated | Not stated |
| NCT00217464 | Fulvestrant in Treating Patients With Recurrent Prostate Cancer | Phase 2 | terminated | Sep 22, 2005 | Roswell Park Cancer Institute | Closed for futility | Efficacy / futility |
| NCT02095847 | High-Resolution Microendoscopy to Guide Hysteroscopic Tumor Resection | Phase 2 | withdrawn | Mar 26, 2014 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT01274572 | Blood for Immune Response to Provenge® in HRPC | — | withdrawn | Jan 11, 2011 | Mary Crowley Medical Research Center | Drug became available with insurance reimbursement | Other (stated, no rule matched) |
| NCT01226290 | Fibroid Ablation Study(FAST-EU) | N/A | terminated | Oct 22, 2010 | Gynesonics | Investigational device changes; adequate enrollment achieved | Enrollment / accrual |
| NCT01267266 | Saracatinib in Treating Patients With Prostate Cancer | Phase 2 | terminated | Dec 28, 2010 | National Cancer Institute (NCI) | Per protocol, study was terminated due to low rate of randomized patients. | Other (stated, no rule matched) |
| NCT01732432 | Endometriosis and Frequency of Endometriosis-associated Ovarian Carcinomas (EAOC)(EAOC) | — | withdrawn | Nov 22, 2012 | University Hospital, Basel, Switzerland | not stated | Not stated |
| NCT00736216 | Knowledge and Perceptions About Human Papillomavirus and Cervical Cancer Risk Among Young… | — | withdrawn | Aug 15, 2008 | Case Comprehensive Cancer Center | PI left the institution | Investigator |
| NCT00659399 | Feasibility Study of Short Term Fondaparinux (Arixtra) in Chemotherapy-Pretreated Ovarian… | Phase 1 | withdrawn | Apr 16, 2008 | NYU Langone Health | Low accrual | Enrollment / accrual |
| NCT01017809 | Prolonged Emend in a Study (NYU 03-67) of Oxaliplatin and Topotecan in Previously Treated… | N/A | withdrawn | Nov 23, 2009 | NYU Langone Health | NYU 03-67 reached accrual prior to this study opening. | Enrollment / accrual |
| NCT01539187 | Fibroid Ablation Study - Large Fibroids(FAST-L) | N/A | terminated | Feb 27, 2012 | Gynesonics | Investigational device changes | Other (stated, no rule matched) |
| NCT01998854 | Observational Prospective Study on Patients With Symptomatic Uterine Fibroids Treated… | — | terminated | Dec 2, 2013 | Gynesonics | Investigational device changes | Other (stated, no rule matched) |
| NCT00442598 | Safety and Efficacy Study of Glufosfamide in Ovarian Cancer | Phase 2 | terminated | Mar 2, 2007 | Eleison Pharmaceuticals LLC. | not stated | Not stated |
| NCT00023634 | S0114 Vaccine Therapy in Treating Patients With Gastric, Prostate, or Ovarian Cancer | Phase 1 | terminated | Jan 27, 2003 | SWOG Cancer Research Network | lack of accrual | Enrollment / accrual |
| NCT00694291 | Sorafenib in Hormone Naïve Biochemical Recurrence of Prostate Cancer | Phase 2 | withdrawn | Jun 10, 2008 | Fox Chase Cancer Center | not stated | Not stated |
| NCT01163448 | Feasibility and Safety Study Using Preoperative High-Dose Single-Fraction Image-Guided… | Phase 1 | withdrawn | Jul 15, 2010 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT01565512 | Dorsal Penile Block for Post-Robotic Prostatectomy Foley Discomfort | Phase 1 / Phase 2 | withdrawn | Mar 28, 2012 | Columbia University | Lack of funding, PI left the institution, poor enrollment | Investigator |
| NCT00058214 | Perifosine in Treating Patients With Recurrent Prostate Cancer | Phase 2 | terminated | Apr 9, 2003 | National Cancer Institute (NCI) | Did not meet interim stopping criteria for continuation to the second stage. | Other (stated, no rule matched) |
| NCT02312804 | Ph Ib/BGJ398/Cervix and Other Solid Tumors | Phase 1 | withdrawn | Dec 9, 2014 | The University of Texas Health Science Center at San Antonio | Drug not available. | Other (stated, no rule matched) |
| NCT00539968 | A Study to Evaluate the Safety, Tolerability, and Activity of Lonafarnib and Docetaxel… | Phase 1 / Phase 2 | terminated | Oct 5, 2007 | Merck Sharp & Dohme LLC | not stated | Not stated |
| NCT02159690 | A Phase II Neoadjuvant Study of Enzalutamide, Abiraterone Acetate, Dutasteride and… | Phase 2 | withdrawn | Jun 10, 2014 | Kenneth Pienta, MD | loss of funding | Funding |
| NCT02065323 | A Study of Dovitinib With Androgen Deprivation Therapy (ADT) in Patients With Metastatic… | Phase 2 | withdrawn | Feb 19, 2014 | Oscar Goodman, Jr. | Terminated due to budgetary considerations and length of development. | Funding |
| NCT00312650 | Doxil and Gemcitabine in Recurrent Ovarian Cancer | Phase 2 | terminated | Apr 10, 2006 | Women and Infants Hospital of Rhode Island | not stated | Not stated |
| NCT00429338 | 3T Endorectal Magnetic Resonance Spectroscopic Imaging (MRSI) of Prostate | N/A | terminated | Jan 31, 2007 | M.D. Anderson Cancer Center | Slow Accrual | Enrollment / accrual |
| NCT00824902 | Evaluation Ultrasound Elasticity/Tissue Strain-Hardening Imaging for Prostate Cancer… | N/A | terminated | Jan 19, 2009 | M.D. Anderson Cancer Center | Technical Issues | Other (stated, no rule matched) |
| NCT00511576 | Study to Evaluate Combination Treatment of MGCD0103 and Docetaxel (Taxotere®) for… | Phase 1 | terminated | Aug 6, 2007 | Mirati Therapeutics Inc. | Celgene terminated its collaboration agreement with MethylGene for the development of MGCD0103. All… | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Jul 22, 2015source: clinicaltrials