Clinical trial · Interventional
Psychosocial Benefits of Exercise in Endometrial Cancer Survivors
NCT01401829CI-TRIAL-00017881terminatedPhase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Terminated due to lack of funding required to continue the study.
Summary
Brief summary (as posted)
To determine if weekly exercise compared to stretching has an effect on fatigue, depression, and anxiety in endometrial cancer survivors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Cancer | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 150 weekly minutes walking | Behavioral | — | UNRESOLVED |
| 75 weekly minutes walking | Behavioral | — | UNRESOLVED |
| Stretching/Flexibility exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- 75 weekly minutes walking
- description
- 12-week physical activity intervention group with a goal of 75 minutes of moderate intensity exercise (walking) per week
- interventionNames
- Behavioral: 75 weekly minutes walking
- type
- EXPERIMENTAL
- label
- 150 weekly minutes walking
- description
- 12 week physical activity intervention group with a goal of 150 minutes of moderate intensity exercise (walking) per week
- interventionNames
- Behavioral: 150 weekly minutes walking
- type
- ACTIVE_COMPARATOR
- label
- Stretching and Flexibility exercise
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * 1\) Female, 18 to 70 years of age with history of Stage I, II, or III endometrial cancer diagnosis occurring at least 6 months prior to study enrollment, * 2\) if chemotherapy or radiation therapy was received, patient must be ≥ 4 weeks post final primary treatment administration, * 3\) if patient has undergone surgical procedure, must be ≥ 8 weeks post-procedure or cleared by surgeon for moderate intensity walking, * 4\) English speaking, * 5\) medical clearance for participation provided by primary care physician or oncologist, * 6\) average fatigue over the past week of ≥3 on a 1 to 10 Likert scale or worrying thoughts ≥ a lot of the time or enjoy the things they used to a little/ not at all. Exclusion Criteria: * 1\) metastatic or recurrent endometrial cancer, * 2\) inability to ambulate without assistance, * 3\) unstable angina, * 4\) New York Heart Association class II, III, or IV congestive heart failure, * 5\) uncontrolled asthma, * 6\) having been told by a physician to only do exercise prescribed by a physician, * 7\) dementia or organic brain syndrome, * 8\) schizophrenia or active psychosis, * 9\) participating, on average, in more than 20 minutes of physical activity on two or more days per week during the past six months, * 10\) anticipates undergoing elective surgery during the duration of the intervention which would interfere with the intervention participation, * 11\) does not live or work less than 50 miles from the study site, * 12\) lack of transportation to the study site, * 13\) plans to move residence out of the local area during the study duration, * 14\) plans to travel out of the local area for more than a week during the intervention, * 15\) contraindication to participation in physical activity, * 16\) non-compliant with sleep apnea treatments.
References
Publications (6)
- BACKGROUNDRogers LQ. Objective monitoring of physical activity after a cancer diagnosis: challenges and opportunities for enhancing cancer control. Phys Ther Rev. 2010 Jun 1;15(3):224-237. doi: 10.1179/174328810X12814016178872. PMID 21603254
- BACKGROUNDRogers LQ, Markwell S, Hopkins-Price P, Vicari S, Courneya KS, Hoelzer K, Verhulst S. Reduced barriers mediated physical activity maintenance among breast cancer survivors. J Sport Exerc Psychol. 2011 Apr;33(2):235-54. doi: 10.1123/jsep.33.2.235. PMID 21558582
- BACKGROUNDRogers LQ, Hopkins-Price P, Vicari S, Markwell S, Pamenter R, Courneya KS, Hoelzer K, Naritoku C, Edson B, Jones L, Dunnington G, Verhulst S. Physical activity and health outcomes three months after completing a physical activity behavior change intervention: persistent and delayed effects. Cancer Epidemiol Biomarkers Prev. 2009 May;18(5):1410-8. doi: 10.1158/1055-9965.EPI-08-1045. Epub 2009 Apr 21. PMID 19383889
- BACKGROUNDRogers LQ, Malone J, Rao K, Courneya KS, Fogleman A, Tippey A, Markwell SJ, Robbins KT. Exercise preferences among patients with head and neck cancer: prevalence and associations with quality of life, symptom severity, depression, and rural residence. Head Neck. 2009 Aug;31(8):994-1005. doi: 10.1002/hed.21053. PMID 19340875
- BACKGROUNDRogers LQ, Courneya KS, Robbins KT, Rao K, Malone J, Seiz A, Reminger S, Markwell SJ, Burra V. Factors associated with fatigue, sleep, and cognitive function among patients with head and neck cancer. Head Neck. 2008 Oct;30(10):1310-7. doi: 10.1002/hed.20873. PMID 18642320
- BACKGROUNDRogers LQ, Markwell SJ, Courneya KS, McAuley E, Verhulst S. Exercise preference patterns, resources, and environment among rural breast cancer survivors. J Rural Health. 2009 Fall;25(4):388-91. doi: 10.1111/j.1748-0361.2009.00249.x. PMID 19780920