Terminated, withdrawn and suspended trials

reasonMatches

clinicaltrialsObservedShowing 51–100 of 124 studies, most recently updated first

NCT	Title	Phase	Status	First posted	Lead sponsor	Why stopped (as posted)	Category
NCT05061940	This SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status…	—	terminated	Sep 30, 2021	Repertoire Immune Medicines	Development program terminated	Other (stated, no rule matched)
NCT01891695	OPSCC N0 Nodal Control With Reduced IMRT	N/A	terminated	Jul 3, 2013	Paul W. Read, MD	Study had very specific inclusion/exclusion criteria and difficult to recruit	Enrollment / accrual
NCT04831450	Phase 2 Trial of Maintenance Cemiplimab for Head and Neck Squamous Cell Carcinoma (HNSCC)	Phase 2	withdrawn	Apr 5, 2021	University of Miami	Investigator Decision	Investigator
NCT04001413	Therapy for High-Risk HPV 16-Positive Oropharynx Cancer Patients	Phase 2	withdrawn	Jun 28, 2019	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Sponsor withdrew funding	Funding
NCT03713021	TraceIT Tissue Marker to Mark the Primary Resection Bed Margins of Oropharyngeal Cancers	N/A	terminated	Oct 19, 2018	Washington University School of Medicine	Equipment unavailable	Other (stated, no rule matched)
NCT02289807	Concurrent Chemotherapy in Intermediate Risk Patients Treated With Intensity-modulated…	N/A	withdrawn	Nov 13, 2014	Sun Yat-sen University	not stated	Not stated
NCT03390738	Nivolumab as Treatment for Recurrent/Metastatic Nasopharyngeal Carcinoma After Failing 2…	Phase 2	withdrawn	Jan 4, 2018	The University of Hong Kong	Sponsor withdrew funding for Nivolumab	Funding
NCT02177838	Cetuximab and Radiation Therapy in Treating Patients With Stage III-IV Head and Neck…	N/A	terminated	Jun 30, 2014	Rutgers, The State University of New Jersey	Slow accrual	Enrollment / accrual
NCT00011492	Patient Evaluation for Head and Neck Surgery Branch Studies	—	terminated	Feb 23, 2001	National Institute on Deafness and Other Communication Disorders (NIDCD)	Closed by Sponsor/Data Safety monitoring Board/IRB	Safety / toxicity
NCT03479463	Use of Human Dehydrated Amnion Chorion Allograft in Laryngectomy/Pharyngectomy	—	terminated	Mar 27, 2018	MiMedx Group, Inc.	Slow enrollment	Enrollment / accrual
NCT04231864	Durvalumab and Epacadostat for Treatment of Unresectable, Recurrent, or Metastatic…	Phase 2	withdrawn	Jan 18, 2020	Alain Algazi	Feasibility	Other (stated, no rule matched)
NCT01249443	Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors…	Phase 1	terminated	Nov 29, 2010	AIDS Malignancy Consortium	Inadequate accrual rate	Enrollment / accrual
NCT00181220	Valproic Acid in the Induction of EBV Lytic Cycle Antigen Expression in Nasopharyngeal…	Phase 1	withdrawn	Sep 16, 2005	Johns Hopkins University	PI left JHU and is not able to be reached for updates	Investigator
NCT00367718	Trial of VELCADE in Patients With Metastatic or Locally Recurrent Nasopharyngeal Carcinoma	Phase 2	withdrawn	Aug 23, 2006	Johns Hopkins University	PI left JHU and is not able to be reached for updates	Investigator
NCT01192815	Erlotinib Hydrochloride and Radiation Therapy in Stage III-IV Squamous Cell Cancer of the…	Phase 2	terminated	Sep 1, 2010	Case Comprehensive Cancer Center	Funding unavailable	Funding
NCT02236936	Parenteral Nutrition for Patients Treated for Locally Advanced Inoperable Tumors of the…(AGMT_HNO_PN)	Phase 3	terminated	Sep 11, 2014	Arbeitsgemeinschaft medikamentoese Tumortherapie	Study stopped due to low recruitment	Enrollment / accrual
NCT02569788	Trail Evaluating Carbon Ion Radiotherapy for Locally Recurrent Nasopharyngeal Carcinoma	Phase 1 / Phase 2	terminated	Oct 7, 2015	Shanghai Proton and Heavy Ion Center	Slow accrual of patients.	Enrollment / accrual
NCT02801487	Trial Evaluating Carbon Ion Radiotherapy With Concurrent Chemotherapy for Locally…	Phase 1 / Phase 2	terminated	Jun 15, 2016	Shanghai Proton and Heavy Ion Center	Slow accrual of patients.	Enrollment / accrual
NCT01883908	Acupuncture in Reducing the Severity of Chemoradiation-induced Mucositis in Patients With…(GCC1229)	N/A	terminated	Jun 21, 2013	University of Maryland, Baltimore	The project is terminated due to that fact that the PI has moved to another institution and there…	Other (stated, no rule matched)
NCT01230476	Induction and Concurrent Chemoradiotherapy With Cetuximab for Patients With Locally…	Phase 2	terminated	Oct 29, 2010	University of Malaya	not stated	Not stated
NCT02062632	Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer…	Phase 2	terminated	Feb 14, 2014	Mayo Clinic	Poor accrual	Enrollment / accrual
NCT02789189	Nedaplatin Combined With Gemcitabine in the Treatment of Recurrent and/or Metastatic…	Phase 2	terminated	Jun 2, 2016	Sun Yat-sen University	not stated	Not stated
NCT03575234	Nivolumab & IRX-2 With Surgery for Resectable Stage III-IVA Oral Cavity Cancer or…	Phase 1	withdrawn	Jul 2, 2018	Emory University	funding and drug were withdrawn	Funding
NCT03611205	Interim Digital PET/CT in Predicting Outcomes for Participants With Locally Advanced…	N/A	withdrawn	Aug 2, 2018	Ohio State University Comprehensive Cancer Center	PI decision	Other (stated, no rule matched)
NCT02137096	Autologous Stem Cell Transplantation for Patients With Recurrent Nasopharyngeal Carcinoma	Phase 3	terminated	May 13, 2014	University of Florida	This is a rare disease, and enrollment was poor.	Enrollment / accrual
NCT02706691	BGJ398 in Treating Patients With FGFR Positive Recurrent Head and Neck Cancer	Phase 2	terminated	Mar 11, 2016	University of Chicago	Study stopped due to poor enrollment.	Enrollment / accrual
NCT00484601	Ifosfamide and Doxorubicin in Patients With Refractory Nasopharyngeal Carcinoma	Phase 2	terminated	Jun 11, 2007	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Low accrual.	Enrollment / accrual
NCT03049358	Olfactory Training in Improving Sense of Smell After Radiation Therapy in Patients With…	N/A	terminated	Feb 10, 2017	Stanford University	Accrual factor	Enrollment / accrual
NCT02388932	Stereotactic Body Radiation Therapy in Treating Patients With High Risk Locally Advanced…	N/A	terminated	Mar 17, 2015	Case Comprehensive Cancer Center	Slow Accrual	Enrollment / accrual
NCT00828386	Induction Chemotherapy and Chemoradiotherapy in Nasopharyngeal Cancers(NPC2006)	Phase 3	terminated	Jan 23, 2009	Groupe Oncologie Radiotherapie Tete et Cou	Low accrual	Enrollment / accrual
NCT01053546	Effects of Swallowing Exercises on Patients Undergoing Radiation Treatment for Head and…	N/A	terminated	Jan 21, 2010	Wake Forest University Health Sciences	slow accrual	Enrollment / accrual
NCT01164566	Esophagoscopy in Evaluating Treatment in Patients With Stage I-IV Head and Neck Cancer…	N/A	terminated	Jul 16, 2010	Wake Forest University Health Sciences	Inadequate Recruitment	Enrollment / accrual
NCT02552550	Swallowing, Speech and Quality of Life of Patients With Carcinoma of the Oropharynx	—	terminated	Sep 17, 2015	Centre Hospitalier Universitaire de Saint Etienne	rate of inclusion too low	Other (stated, no rule matched)
NCT02628912	Cardiopulmonary Fitness in Long-Term Survivors of HPV-related Oropharynx Cancers	—	withdrawn	Dec 11, 2015	Memorial Sloan Kettering Cancer Center	Lack of accrual	Enrollment / accrual
NCT02225496	Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma	Phase 2	terminated	Aug 26, 2014	M.D. Anderson Cancer Center	Another trial in the department directly competes for the the same patient population	Other (stated, no rule matched)
NCT02022293	Atorvastatin in Preventing Nasopharyngeal Carcinoma Patients Receiving Radiotherapy From…	Phase 2	suspended	Dec 27, 2013	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Enrollment target could not be achieved.	Enrollment / accrual
NCT02298595	Cetuximab, Cisplatin and BYL719 for HPV-Associated Oropharyngeal Squamous Cell Carcinoma	Phase 1 / Phase 2	withdrawn	Nov 24, 2014	Julie E. Bauman, MD, MPH	not stated	Not stated
NCT02068157	Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer	Phase 2	terminated	Feb 21, 2014	Roswell Park Cancer Institute	Study no longer has an active IDE	Other (stated, no rule matched)
NCT01767961	Modified Barium Swallow in Measuring Swallowing Function After Surgery in Patients With…	N/A	withdrawn	Jan 15, 2013	Wake Forest University Health Sciences	Unable to secure funding.	Funding
NCT00895245	Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing…	Phase 2	terminated	May 8, 2009	University of Washington	Study stopped due to lack of efficacy in first 6 patients	Efficacy / futility
NCT02196168	Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or…	Phase 2	terminated	Jul 21, 2014	National Cancer Institute (NCI)	Inadequate accrual rate	Enrollment / accrual
NCT01267240	Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head…	Phase 2	terminated	Dec 28, 2010	National Cancer Institute (NCI)	Study treatment did not show clinical activity.	Other (stated, no rule matched)
NCT00797290	Photon/Proton Radiation Therapy for Carcinoma of the Nasopharynx(NP01)	—	terminated	Nov 25, 2008	University of Florida	Slow enrollment, Feasibility issues	Enrollment / accrual
NCT00797446	Photon/Proton Radiation Therapy for Oropharyngeal Cancers(OP01)	—	terminated	Nov 25, 2008	University of Florida	Slow enrollment, feasibility issues	Enrollment / accrual
NCT01283178	Phase I Study of IMRT and Molecular-Image Guided Adaptive Radiation Therapy for Advanced…	Phase 1	terminated	Jan 25, 2011	Virginia Commonwealth University	The study was terminated. The data analysis was futile with only 3 accruals. PI opted to terminate…	Enrollment / accrual
NCT01528137	Talactoferrin in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer…	Phase 1	terminated	Feb 7, 2012	Stanford University	Negative data from another trial led to termination of this trial by sponsor.	Other (stated, no rule matched)
NCT02334319	Ganetespib Window of Opportunity Study in Head and Neck Cancers	Phase 1	terminated	Jan 8, 2015	Emory University	Lack of funding	Funding
NCT02080416	Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors	Early Phase 1	terminated	Mar 6, 2014	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Very slow accrual; terminated to allow resources to be utilized more effectively on other studies.…	Enrollment / accrual
NCT00537199	OraTest in Combination With Visual Examination and Visual Examination Alone	Phase 3	terminated	Sep 28, 2007	M.D. Anderson Cancer Center	Study terminated early as per request by sponsor, Zila Biotechnology, Inc.	Other (stated, no rule matched)
NCT02119728	Photodynamic Therapy With HPPH in Treating Patients With Squamous Cell Carcinoma of the…	Phase 2	withdrawn	Apr 22, 2014	Roswell Park Cancer Institute	not stated	Not stated

Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.

Data updated 22 days agoSource updated Dec 6, 2022source: clinicaltrials

Terminated, withdrawn and suspended studies

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