Clinical trial · Observational
Swallowing, Speech and Quality of Life of Patients With Carcinoma of the Oropharynx
Analysis of Swallowing, Speech and Quality of Life of Patients With Stage T3-T4 Squamous Cell Carcinoma of the Oropharynx Before and After Multimodal Treatment With Curative Intent
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): rate of inclusion too low
Summary
Brief summary (as posted)
The curative treatment and organ preservation in advanced squamous cell carcinoma of the oropharynx is multimodal. It involves induction chemotherapy and depending on the response radio-chemotherapy or surgery. The combination of these methods has important functional consequences. The aim of this prospective pilot study is to describe swallowing, speech, but also patients' quality of life before and after therapeutic management (existing studies measuring these functions after treatment but not before).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Squamous Cell Carcinoma of the Oropharynx | Oropharyngeal Squamous Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ability to swallow, speak and quality of life | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Ability to swallow, speak and quality of life
- description
- This will just be an evaluation, before any treatment, his ability to swallow, speak and quality of life then, as in normal practice, after 3, 6 and 12 months after treatment.
- interventionNames
- Procedure: Ability to swallow, speak and quality of life
Primary outcomes (1)
- measure
- change from swallowing disorder
- timeFrame
- between day 0 and 1 year
- description
- A swallowing disorder will be determined by conducting a video-endoscopy and voluntary swallowing reflex (composite measure)
Secondary outcomes (2)
- measure
- Change from phonation disorder
- timeFrame
- between day 0 and 1 year
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Patient with stage T3 or T4 squamous cell carcinoma of the oropharynx previously untreated. * Performance status 0 or 1 * Tumor histology proving squamous cell carcinoma Exclusion Criteria: * Visceral metastases at initial assessment * Contraindication to surgery and / or chemotherapy such as: * A history of other cancer (except basal cell carcinoma skin or cervical cancer in situ) * 2nd associated cancer
References
Publications (0)
Data not yet available