Loading clinical trials…
Loading clinical trials…
Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
204 stopped studies mapped to Malignant Neck Neoplasm and descendants · 91% state a reason
Over the 204 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computed
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02437513 | NewBreez for Airway Protection in Head and Neck Cancer Patients With Chronic Aspiration | — | terminated | May 7, 2015 | ProTiP Medical | Recruitment rates too low to continue with the study | Enrollment / accrual |
| NCT02778412 | ctDNA in Patients With Thyroid Nodules | — | terminated | May 19, 2016 | Pathway Genomics | Preliminary results indicated that this test had a number of false-negative results. | Other (stated, no rule matched) |
| NCT01767961 | Modified Barium Swallow in Measuring Swallowing Function After Surgery in Patients With… | N/A | withdrawn | Jan 15, 2013 | Wake Forest University Health Sciences | Unable to secure funding. | Funding |
| NCT02726282 | Impact of Papillary Microcarcinoma Terminology on Patients Treatment Preferences: a Cross… | — | withdrawn | Apr 1, 2016 | Mayo Clinic | funding not available | Funding |
| NCT00895245 | Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing… | Phase 2 | terminated | May 8, 2009 | University of Washington | Study stopped due to lack of efficacy in first 6 patients | Efficacy / futility |
| NCT02196168 | Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or… | Phase 2 | terminated | Jul 21, 2014 | National Cancer Institute (NCI) | Inadequate accrual rate | Enrollment / accrual |
| NCT01267240 | Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head… | Phase 2 | terminated | Dec 28, 2010 | National Cancer Institute (NCI) | Study treatment did not show clinical activity. | Other (stated, no rule matched) |
| NCT01865838 | A Study Into the Effect of Seprafilm in Open Total Thyroidectomy | N/A | terminated | May 31, 2013 | National Cancer Centre, Singapore | safety issue | Safety / toxicity |
| NCT00797290 | Photon/Proton Radiation Therapy for Carcinoma of the Nasopharynx(NP01) | — | terminated | Nov 25, 2008 | University of Florida | Slow enrollment, Feasibility issues | Enrollment / accrual |
| NCT00797446 | Photon/Proton Radiation Therapy for Oropharyngeal Cancers(OP01) | — | terminated | Nov 25, 2008 | University of Florida | Slow enrollment, feasibility issues | Enrollment / accrual |
| NCT01283178 | Phase I Study of IMRT and Molecular-Image Guided Adaptive Radiation Therapy for Advanced… | Phase 1 | terminated | Jan 25, 2011 | Virginia Commonwealth University | The study was terminated. The data analysis was futile with only 3 accruals. PI opted to terminate… | Enrollment / accrual |
| NCT01910753 | Physical Activity Program and Nutrition Therapeutic Education During Treatment of Head…(APANVADS) | N/A | terminated | Jul 30, 2013 | University Hospital, Limoges | Not enough patients | Other (stated, no rule matched) |
| NCT01528137 | Talactoferrin in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer… | Phase 1 | terminated | Feb 7, 2012 | Stanford University | Negative data from another trial led to termination of this trial by sponsor. | Other (stated, no rule matched) |
| NCT02334319 | Ganetespib Window of Opportunity Study in Head and Neck Cancers | Phase 1 | terminated | Jan 8, 2015 | Emory University | Lack of funding | Funding |
| NCT01403324 | Comparison of Dosimetry After rhTSH or Withdrawal of Thyroid Hormone in Metastatic or…(DOSIMETA) | N/A | terminated | Jul 27, 2011 | Gustave Roussy, Cancer Campus, Grand Paris | Recruitment difficulties | Enrollment / accrual |
| NCT02080416 | Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors | Early Phase 1 | terminated | Mar 6, 2014 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Very slow accrual; terminated to allow resources to be utilized more effectively on other studies.… | Enrollment / accrual |
| NCT00537199 | OraTest in Combination With Visual Examination and Visual Examination Alone | Phase 3 | terminated | Sep 28, 2007 | M.D. Anderson Cancer Center | Study terminated early as per request by sponsor, Zila Biotechnology, Inc. | Other (stated, no rule matched) |
| NCT02119728 | Photodynamic Therapy With HPPH in Treating Patients With Squamous Cell Carcinoma of the… | Phase 2 | withdrawn | Apr 22, 2014 | Roswell Park Cancer Institute | not stated | Not stated |
| NCT01994200 | Developing and Implementing an Interdisciplinary Team-Based Care Approach (ITCA-ThyCa)…(ITCA-ThyCa) | Phase 1 / Phase 2 | withdrawn | Nov 25, 2013 | Jewish General Hospital | not stated | Not stated |
| NCT02516774 | A Trial of Adalimumab Combined to Chemotherapy and Radiotherapy in Patients With…(TAM-RT) | Phase 1 | withdrawn | Aug 6, 2015 | Gustave Roussy, Cancer Campus, Grand Paris | No patients enrolled | Enrollment / accrual |
| NCT00599131 | Cetuximab and Radiation Therapy in Laryngeal Cancer Patients Who Have Responded to One… | Phase 2 | terminated | Jan 23, 2008 | University of Michigan Rogel Cancer Center | The study was discontinued prematurely due to early stopping rules. | Other (stated, no rule matched) |
| NCT01586182 | Stereotactic Boost for Oropharyngeal Squamous Cell Carcinoma | Phase 1 / Phase 2 | withdrawn | Apr 26, 2012 | Dana-Farber Cancer Institute | Local IRB closed the study due to poor accural. | Other (stated, no rule matched) |
| NCT01949740 | Patient Preferences in Making Treatment Decisions in Patients With Stage I-IVA… | — | terminated | Sep 24, 2013 | University of Chicago | Poor accrual | Enrollment / accrual |
| NCT02058017 | OPB-51602 in Locally Advanced Nasopharyngeal Carcinoma Prior to Definitive… | Phase 1 | terminated | Feb 7, 2014 | National University Hospital, Singapore | Lactic and metabolic acidosis of OPB-51602 is not tolerable | Other (stated, no rule matched) |
| NCT01694576 | NPC Staged N2-3M0:Adjuvant Chemotherapy or Just Observation After Concurrent… | Phase 2 | terminated | Sep 27, 2012 | Jiangsu Cancer Institute & Hospital | slow patient enrollment | Enrollment / accrual |
| NCT02156180 | Identification of Breath Biomarkers in Head and Neck Squamous Cell Carcinoma | — | suspended | Jun 5, 2014 | Queensland Centre of Excellence for Head and Neck Cancer | Awaiting funding to facilitate selected-ion flow-tube mass spectrometry (SIFT/MS) | Funding |
| NCT01153945 | Association Between Cancer Cells and Normal Versus (Vs.) Low Levels of Thyroid Hormones… | — | withdrawn | Jun 30, 2010 | Meir Medical Center | The sponsor stopped the study. | Other (stated, no rule matched) |
| NCT01953952 | Radiation Therapy and Cisplatin With or Without Surgery in Treating Patients With Stage… | Phase 2 | withdrawn | Oct 1, 2013 | Radiation Therapy Oncology Group | Slow accrual | Enrollment / accrual |
| NCT00354523 | Imatinib in Combination With Dacarbazine and Capecitabine in Medullary Thyroid Carcinoma | Phase 1 / Phase 2 | terminated | Jul 20, 2006 | M.D. Anderson Cancer Center | Study closed following Phase I portion, insufficient activity to continue to Phase II. | Other (stated, no rule matched) |
| NCT01254734 | Transoral Robotic Surgery in Treating Patients With Benign or Stage I-IV Head and Neck… | N/A | terminated | Dec 7, 2010 | City of Hope Medical Center | The study will be rewritten as a data registry study | Other (stated, no rule matched) |
| NCT01718223 | Photodynamic Therapy Using Temoporfin Before Surgery in Treating Patients With Recurrent… | N/A | withdrawn | Oct 31, 2012 | Roswell Park Cancer Institute | implementation issues | Other (stated, no rule matched) |
| NCT01682031 | Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck… | Phase 2 | terminated | Sep 10, 2012 | Roswell Park Cancer Institute | Due to a lack of funding | Funding |
| NCT01403259 | SOX as Salvage Treatment in Nasopharyngeal Carcinoma | Phase 2 | terminated | Jul 27, 2011 | Fudan University | poor accrual of eligible patients | Enrollment / accrual |
| NCT01175499 | Concordance of Two Endoscopic Procedures for Diagnosis of Carcinoma of the Upper…(TNFE-NBI) | N/A | withdrawn | Aug 4, 2010 | University of California, San Francisco | Unable to obtain funding to continue recruitment; no accrual | Enrollment / accrual |
| NCT00507429 | Study of Combretastatin and Paclitaxel/Carboplatin in the Treatment of Anaplastic Thyroid…(FACT) | Phase 2 / Phase 3 | terminated | Jul 26, 2007 | Mateon Therapeutics | Low rate of subject accrual | Enrollment / accrual |
| NCT01701349 | Fosbretabulin or Placebo in Combination With Carboplatin/Paclitaxel in Anaplastic Thyroid…(FACT2) | Phase 3 | withdrawn | Oct 5, 2012 | Mateon Therapeutics | Expected inability to recruit study participants in a reasonable amount of time. | Enrollment / accrual |
| NCT00115739 | Trial Evaluating Gleevec in Patients With Anaplastic Thyroid Carcinoma | Phase 2 | terminated | Jun 24, 2005 | University of Michigan Rogel Cancer Center | Study was closed early due to slow accrual | Enrollment / accrual |
| NCT00095693 | Sorafenib Tosylate in Treating Patients With Locally Advanced, Metastatic, or Locally… | Phase 2 | terminated | Nov 8, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01728480 | Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer… | Phase 1 | withdrawn | Nov 19, 2012 | Roswell Park Cancer Institute | Financial Sponsor requested termination | Funding |
| NCT00095641 | S0225 Capecitabine in Treating Patients Who Have Undergone Surgery for Locally Recurrent… | Phase 2 | withdrawn | Nov 8, 2004 | SWOG Cancer Research Network | no longer studying this disease site | Other (stated, no rule matched) |
| NCT00006106 | ONYX-015 With Cisplatin and Fluorouracil in Treating Patients With Advanced Head and Neck… | Phase 1 | withdrawn | Apr 29, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00906360 | Sunitinib, Cetuximab, and Radiation Therapy in Treating Patients With Locally Advanced or… | Phase 1 | terminated | May 21, 2009 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00954837 | Assessment of Repeat Fine Needle Aspiration (FNA) to Detect Thyroid Cancer(CYT2THYR) | N/A | withdrawn | Aug 7, 2009 | Assistance Publique - Hôpitaux de Paris | administrative delays too long | Other (stated, no rule matched) |
| NCT01736878 | Efficacy and Safety Study of Sorafenib to Treat Advanced Medullary Thyroid Carcinoma(SUMMIT) | Phase 2 | withdrawn | Nov 29, 2012 | Eanm Research Ltd | Study was withdrawn due to unanticipated hassle in patient recruitment. | Enrollment / accrual |
| NCT01674374 | Botanical Therapy in Treating Mucositis in Patients With Head and Neck Cancer Who Have… | Phase 2 | withdrawn | Aug 28, 2012 | Roswell Park Cancer Institute | not stated | Not stated |
| NCT00033449 | Gefitinib and Radiation Therapy With or Without Cisplatin in Treating Patients With Stage… | Phase 1 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00081211 | Intratumoral PV701 in Treating Patients With Advanced or Recurrent Unresectable Squamous… | Phase 1 | terminated | Apr 8, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT01066741 | Prevention of Radiation-induced Severe Oral Mucositis in Oral Cavity, Oropharynx,… | Phase 3 | terminated | Feb 10, 2010 | Centre Leon Berard | insufficient recruitment, the planed sample size appears not achievable | Enrollment / accrual |
| NCT00928161 | Reflux Disease in Head and Neck Cancer Patients Undergoing Radiation Therapy | N/A | withdrawn | Jun 25, 2009 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00951470 | Complete Decongestive Therapy (CDT) for Treatment of Head and Neck Lymphedema | N/A | withdrawn | Aug 4, 2009 | M.D. Anderson Cancer Center | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Aug 24, 2017source: clinicaltrials