Clinical trial · Interventional
NPC Staged N2-3M0:Adjuvant Chemotherapy or Just Observation After Concurrent Chemoradiation
Adjuvant Chemotherapy or Not for NPC Patients Staged N2-3M0 After Concurrent Chemotherapy :a Phase Ⅱ Study
NCT01694576CI-TRIAL-00018256terminatedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): slow patient enrollment
Summary
Brief summary (as posted)
By this clinical trial, the investigators are trying to give an answer to such a question. Whether NPC patients staged N2-3M0 need adjuvant chemotherapy consisting of paclitaxel and platinum after concurrent chemoradiation?
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Nasopharyngeal Carcinoma | Nasopharyngeal Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Adjuvant chemotherapy with paclitaxel and nedaplatin | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Adjuvant chemotherapy with paclitaxel and nedaplatin
- description
- Patients will receive 3 cycles of adjuvant chemotherapy consisting of paclitaxel and platinum after concurrent chemoradiation
- interventionNames
- Drug: Adjuvant chemotherapy with paclitaxel and nedaplatin
- type
- NO_INTERVENTION
- label
- Observation
- description
- Patients will be followed up without adjuvant chemotherapy after concurrent chemoradiation
Primary outcomes (1)
- measure
- treatment toxicity based on a CTCAE3.0 grading system
- timeFrame
- 6 months
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: 1. pathologically confirmed untreated NPC patients staged N2-3M0 2. age: 18y - 65y 3. with MRI examinations 4. ECOG≤2 5. with written consent Exclusion Criteria: 1. without a second cancer 2. pregnancy 3. with other severe diseases(blood,liver ,kidney or heart diseases) 4. could not staged properly 5. without written consent
References
Publications (0)
Data not yet available
No reference posted for this study.