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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
826 stopped studies mapped to Malignant Female Reproductive System Neoplasm and descendants · 86% state a reason
Over the 826 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02736435 | Treatment of Uterine Fibroids With Magnetic Resonance Guided High Intensity Focused… | Phase 3 | withdrawn | Apr 13, 2016 | Thunder Bay Regional Health Research Institute | Lengthy delays and inadequate support to proceed. | Other (stated, no rule matched) |
| NCT00303888 | Docetaxel With or Without Phenoxodiol in Treating Patients With Recurrent Advanced… | Phase 1 | terminated | Mar 17, 2006 | Yale University | not stated | Not stated |
| NCT00574951 | AMG 706 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer,… | Phase 2 | terminated | Dec 17, 2007 | Gynecologic Oncology Group | Study was stopped for severe toxicity causing concern for patients | Safety / toxicity |
| NCT00375804 | Racial Disparity in Endometrial Cancer | — | terminated | Sep 13, 2006 | University of Louisville | Funding and logistical difficuties resulted in the withdrawl of the study. | Funding |
| NCT00585052 | A Phase II Study of Interaction of Lovastatin and Paclitaxel For Patients With Refractory… | Phase 2 | terminated | Jan 2, 2008 | University of Iowa | Slow accrual, PI left the institution | Investigator |
| NCT00720096 | Genomic Directed Salvage Chemotherapy With Either Liposomal Doxorubicin Or Topotecan | N/A | terminated | Jul 22, 2008 | H. Lee Moffitt Cancer Center and Research Institute | Funds for this project have been spent, and it is thereby terminated. | Funding |
| NCT00331422 | Carboplatin, Paclitaxel, and Surgery in Treating Patients With Advanced Ovarian… | Phase 2 | terminated | May 31, 2006 | Masonic Cancer Center, University of Minnesota | Study was terminated due to lack of available funding. | Funding |
| NCT00602446 | Deferasirox in Treating Patients With Iron Overload After Undergoing a Donor Stem Cell… | Phase 2 | terminated | Jan 28, 2008 | Masonic Cancer Center, University of Minnesota | Due to slow accrual of patients | Enrollment / accrual |
| NCT00652899 | Allogeneic Natural Killer Cells in Patients With Recurrent Ovarian Cancer, Fallopian… | Phase 2 | terminated | Apr 4, 2008 | Masonic Cancer Center, University of Minnesota | Withdrawn due to toxicity | Safety / toxicity |
| NCT00903630 | Lenalidomide and Doxorubicin Hydrochloride Liposome in Recurrent Ovarian Epithelial… | Phase 1 / Phase 2 | terminated | May 18, 2009 | Masonic Cancer Center, University of Minnesota | lack of funding | Funding |
| NCT00003532 | Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Ovarian Cancer | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | Slow accrual | Enrollment / accrual |
| NCT01575444 | Cervical Cancer Screening Project Part C | — | terminated | Apr 11, 2012 | University of Minnesota | Investigator left University No results are possible | Investigator |
| NCT01281254 | AMG 386 (Trebananib) in Ovarian Cancer (TRINOVA-2) | Phase 3 | terminated | Jan 21, 2011 | Amgen | Closure of long term follow up (LTFU) and study earlier than previously outlined in the protocol as… | Other (stated, no rule matched) |
| NCT00003926 | Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors | Phase 1 | terminated | May 2, 2003 | Masonic Cancer Center, University of Minnesota | Withdrawn due to slow accrual | Enrollment / accrual |
| NCT00287859 | Topotecan in Treating Patients With Ovarian Epithelial, Fallopian Tube, or Primary… | Phase 1 | terminated | Feb 7, 2006 | Masonic Cancer Center, University of Minnesota | Withdrawn due to low accrual | Enrollment / accrual |
| NCT00428194 | Erlotinib, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB-Stage IVA… | Phase 1 | withdrawn | Jan 29, 2007 | Masonic Cancer Center, University of Minnesota | Withdrawn due to lack of accrual | Enrollment / accrual |
| NCT00278434 | Zoledronate in Treating Patients With Cervical Intraepithelial Neoplasia 2/3 or 3 | Phase 1 | terminated | Jan 18, 2006 | University of California, San Francisco | Accrual was insufficient to meet study endpoints | Enrollment / accrual |
| NCT00562185 | Doxorubicin and Carboplatin in Treating Patients With Recurrent Ovarian Cancer | Phase 1 / Phase 2 | withdrawn | Nov 21, 2007 | University of Texas Southwestern Medical Center | Funding source withdrew funding | Funding |
| NCT00070317 | Lymph Node Mapping and Sentinel Lymph Node Identification in Patients With Stage IB1… | N/A | terminated | Oct 7, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT03032614 | Combination of Carboplatin, Eribulin and Veliparib in Stage IV Cancer Patients | Phase 2 | withdrawn | Jan 26, 2017 | The University of Texas Health Science Center at San Antonio | Lack of funding | Funding |
| NCT02278783 | Phase 2 Trial of Regorafenib in Patients With Recurrent Ovarian, Primary Peritoneal and… | Phase 2 | terminated | Oct 30, 2014 | University of Utah | Slow Accrual | Enrollment / accrual |
| NCT03007771 | Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild… | Phase 1 | withdrawn | Jan 2, 2017 | Washington University School of Medicine | Decision was made to not go forward with the study | Other (stated, no rule matched) |
| NCT00003525 | Antineoplaston Therapy in Treating Patients With Stage IV Cancer of the Cervix and/or… | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | slow accrual | Enrollment / accrual |
| NCT00354601 | Docetaxel and Capecitabine in Treating Patients With Recurrent or Persistent Ovarian… | Phase 2 | terminated | Jul 20, 2006 | Wake Forest University Health Sciences | funding withdrawn | Funding |
| NCT00600210 | Neoadjuvant Bevacizumab and Carboplatin Followed by Concurrent Bevacizumab, Carboplatin… | Phase 2 | withdrawn | Jan 24, 2008 | Leo W. Jenkins Cancer Center | low patient accrual | Enrollment / accrual |
| NCT01991210 | A Study of DNIB0600A in Comparison With Pegylated Liposomal Doxorubicin (PLD) in… | Phase 2 | terminated | Nov 25, 2013 | Genentech, Inc. | The primary objective of PFS did not meet pre-specified criteria. | Other (stated, no rule matched) |
| NCT00408967 | Determine if Either of 2 Doses of Study Drug Given With a Low-dose of Cyclophosphamide… | Phase 2 | withdrawn | Dec 8, 2006 | EMD Serono | Th trial got cancelled and no subjects signed informed consent form (ICF); study design not… | Other (stated, no rule matched) |
| NCT01842789 | Post Market Evaluation of Acessa With TAG(TAG) | N/A | terminated | Apr 30, 2013 | Acessa Health, Inc. | Results to date adequately demonstrated user preference and recovery time. Time to target (Part II)… | Other (stated, no rule matched) |
| NCT00004221 | Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients… | Phase 2 | terminated | Aug 25, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT02223975 | Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease(Vulval VS) | — | suspended | Aug 22, 2014 | Gloucestershire Hospitals NHS Foundation Trust | Study suspended pending further funding | Funding |
| NCT00900081 | Cyclooxygenase-2 Expression in Tissue Samples From Patients With a Normal Cervix,… | — | withdrawn | May 12, 2009 | Wake Forest University Health Sciences | no accrual, PI left institution | Investigator |
| NCT01641497 | Phase III Study Comparing 3D Conformal Radiotherapy and Conformal Radiotherapy IMRT to…(TOMOGYN) | N/A | terminated | Jul 16, 2012 | Centre Oscar Lambret | Recruitment difficulties | Enrollment / accrual |
| NCT02093871 | A Phase 1 Trial of Perfusion Induced Systemic Hyperthermia (PISH) Over Multiple Cycles…(PISH-2) | Phase 1 | suspended | Mar 21, 2014 | ThermalCore Inc | not stated | Not stated |
| NCT00551265 | Oregovomab With or Without Cyclophosphamide in Treating Patients With Stage III or Stage… | N/A | withdrawn | Oct 30, 2007 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003865 | Toremifene in Treating Patients With Ovarian Cancer | Phase 2 | withdrawn | Jan 27, 2003 | George Washington University | not stated | Not stated |
| NCT01754519 | Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer… | Phase 2 | terminated | Dec 21, 2012 | Roswell Park Cancer Institute | IDE not submitted | Other (stated, no rule matched) |
| NCT01176500 | A Pilot, Open-label Study of 18F-Fluciclatide PET/CT Imaging in the Evaluation of… | Phase 1 / Phase 2 | withdrawn | Aug 6, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01386502 | CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors | Phase 1 | withdrawn | Jul 1, 2011 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01184053 | Trisenox® in Women With Metastatic Endometrial Cancer(NRR) | Phase 2 | terminated | Aug 18, 2010 | UNC Lineberger Comprehensive Cancer Center | Accrual was very low. No subject had been enrolled in a year. | Enrollment / accrual |
| NCT01972516 | Tivozanib As Maintenance Therapy In GYN | Phase 2 | terminated | Oct 30, 2013 | Dana-Farber Cancer Institute | due to slow accrual | Enrollment / accrual |
| NCT01461772 | Efficacy and Safety Study of Concurrent Chemoradiation Therapy to Treat Locally Advanced… | Phase 3 | terminated | Oct 28, 2011 | Asan Medical Center | Because of very slow rate of enrollement | Enrollment / accrual |
| NCT01681368 | Birinapant for Advanced Ovarian, Fallopian Tube, and Peritoneal Cancer | Phase 2 | terminated | Sep 7, 2012 | National Cancer Institute (NCI) | Accrual was terminated for lack of a clinical benefit. | Enrollment / accrual |
| NCT02417753 | AZD9150, a STAT3 Antisense Oligonucleotide, in People With Malignant Ascites | Phase 2 | terminated | Apr 16, 2015 | National Cancer Institute (NCI) | Study was closed because we could not find these types of patients. | Other (stated, no rule matched) |
| NCT00324324 | Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem… | Phase 3 | terminated | May 11, 2006 | OHSU Knight Cancer Institute | not stated | Not stated |
| NCT00900068 | Blood Samples From Patients on a Clinical Trial to CINV During HSCT | — | terminated | May 12, 2009 | OHSU Knight Cancer Institute | not stated | Not stated |
| NCT00603460 | DCVax-L Vaccination With CD3/CD28 Costimulated Autologous T-Cells for Recurrent Ovarian… | Phase 1 / Phase 2 | withdrawn | Jan 29, 2008 | University of Pennsylvania | not stated | Not stated |
| NCT02742428 | Preoperative Ascites Drainage Versus Standard Care for Patients With Advanced Ovarian… | N/A | suspended | Apr 19, 2016 | Gdynia Oncology Center | The protocol will be discussed and consulted. Potentially will resume. | Other (stated, no rule matched) |
| NCT01494012 | Phase I Stereotactic Body Radiation for Metastatic or Recurrent Platinum-Resistant… | Phase 1 | terminated | Dec 16, 2011 | Stanford University | low accrual | Enrollment / accrual |
| NCT02338141 | Accuracy of Portable Colposcopy and HPV Genotypes Among HIV+ Women | N/A | terminated | Jan 14, 2015 | Duke University | Funding unavailable to perform study. | Funding |
| NCT02704650 | Identification and Characterization of Ovarian Cancer and Endometrial Cancer Specific… | N/A | withdrawn | Mar 10, 2016 | Shaare Zedek Medical Center | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Feb 6, 2018source: clinicaltrials