Loading clinical trials…
Loading clinical trials…
Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
2,226 stopped studies mapped to Malignant Digestive System Neoplasm and descendants · 91% state a reason
Over the 2,226 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00033306 | BMS-247550 in Treating Patients With Metastatic Colorectal Cancer | Phase 2 | terminated | Aug 6, 2003 | University of Alabama at Birmingham | not stated | Not stated |
| NCT00708877 | Liver Transplantation for Cholangiocarcinoma | N/A | terminated | Jul 2, 2008 | University of Utah | study procedures have become standard of care as patients seeking Model for End-Stage Liver Disease… | Other (stated, no rule matched) |
| NCT00026468 | Exisulind in Preventing Polyps in Patients With Familial Adenomatous Polyposis | Phase 2 / Phase 3 | withdrawn | Jan 27, 2003 | University of Utah | Principle Investigator has left the University. | Investigator |
| NCT00003486 | Antineoplaston Therapy in Treating Patients With Colon Cancer | Phase 2 | withdrawn | Jan 27, 2003 | Burzynski Research Institute | not stated | Not stated |
| NCT00003514 | Antineoplaston Therapy in Treating Patients With Neuroendocrine Tumor That Is Metastatic… | Phase 2 | withdrawn | Jan 27, 2003 | Burzynski Research Institute | not stated | Not stated |
| NCT00896467 | Psychological and Emotional Impact in Patients Undergoing Treatment For Metastatic Cancer… | — | terminated | May 11, 2009 | Centre Oscar Lambret | not stated | Not stated |
| NCT00932724 | CY-503 for the Treatment of Chemotherapy-refractory Metastatic Colorectal Cancer(CY503C2) | Phase 2 | terminated | Jul 3, 2009 | Cytavis Biopharma GmbH | The sponsor declared the early termination of the study due to poor recruitment of patients. | Enrollment / accrual |
| NCT00098527 | FR901228 in Treating Patients With Refractory Stomach Cancer or Gastroesophageal Junction… | Phase 2 | terminated | Dec 8, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01282333 | Veliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced… | Phase 1 | terminated | Jan 25, 2011 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01600807 | OSI-906 With Gemcitabine and Erlotinib for Metastatic Ductal Adenocarcinoma of the… | Phase 1 / Phase 2 | withdrawn | May 17, 2012 | Dana-Farber Cancer Institute | Study was pending major changes and was on hold, pending activation; administratively withdrawn;… | Other (stated, no rule matched) |
| NCT00587132 | Secretin (ChiRhoStim) Pancreas Perfusion for Pancreatic Adenocarcinoma | Phase 1 / Phase 2 | terminated | Jan 7, 2008 | Mayo Clinic | Lack of funding | Funding |
| NCT01017822 | Conatumumab, Gemcitabine Hydrochloride, Capecitabine, and Radiation Therapy in Treating… | Phase 1 / Phase 2 | withdrawn | Nov 23, 2009 | Radiation Therapy Oncology Group | This study was withdrawn due to study agent availability. | Other (stated, no rule matched) |
| NCT00049608 | Gemcitabine Combined With Mistletoe in Treating Patients With Advanced Solid Tumors | Phase 1 | terminated | Jan 27, 2003 | National Center for Complementary and Integrative Health (NCCIH) | Principal investigator \[PI\] has left institution. | Investigator |
| NCT00908024 | Combination Study of BMS-754807 and Erbitux® in Subjects With Advanced or Metastatic… | Phase 1 / Phase 2 | terminated | May 25, 2009 | Bristol-Myers Squibb | not stated | Not stated |
| NCT01257035 | Predictive Value of 18F-FAZA in Rectum Cancer(FAZA) | — | terminated | Dec 9, 2010 | Vejle Hospital | The logistics of this trial (incl. supply of tracer) in connection with the patients' treatment… | Drug supply |
| NCT00671463 | Pancreatic Stent to Prevent Leak After Distal Pancreatectomy(LEAPS) | N/A | withdrawn | May 5, 2008 | Massachusetts General Hospital | Anticipated high risk of pancreatitis | Other (stated, no rule matched) |
| NCT01872104 | Safety and Efficiency of Photodynamic Therapy for Rectal Cancer(PDT-R-01) | Phase 2 / Phase 3 | suspended | Jun 7, 2013 | li xiong | Modifying the clinnicaltrials | Other (stated, no rule matched) |
| NCT01293942 | IXO+A in mCRC With Liver-only Metastases | Phase 2 | withdrawn | Feb 11, 2011 | Ottawa Hospital Research Institute | not stated | Not stated |
| NCT00084461 | Romidepsin in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors | Phase 2 | terminated | Jun 11, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00103272 | 17-N-Allylamino-17-Demethoxygeldanamycin and Bortezomib in Treating Patients With… | Phase 1 | terminated | Feb 8, 2005 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00006001 | SU5416 in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer | Phase 2 | terminated | May 26, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00238160 | Surgery With or Without Hepatic Arterial Chemotherapy in Treating Patients With Liver… | Phase 3 | withdrawn | Oct 13, 2005 | Kyoto University | not stated | Not stated |
| NCT01032291 | A Study to Assess the Efficacy and Safety of Lenalidomide in Combination With Cetuximab… | Phase 2 | terminated | Dec 15, 2009 | Celgene Corporation | A business decision not to continue with Phase 2b based on non-safety observations during proof of… | Safety / toxicity |
| NCT01859169 | Safety and Efficiency of Photodynamic Therapy for Blie Duct Carcinoma | — | suspended | May 21, 2013 | li xiong | Modifying the clinnicaltrials | Other (stated, no rule matched) |
| NCT00012246 | Vaccine Therapy in Treating Patients With Cancer of the Gastrointestinal Tract | Phase 2 | terminated | Jan 27, 2003 | The University of Texas Medical Branch, Galveston | Administratively Terminated | Other (stated, no rule matched) |
| NCT00354185 | PXD101 and 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic… | Phase 1 | terminated | Jul 20, 2006 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01707758 | Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence | — | withdrawn | Oct 16, 2012 | University of Kansas | Trial terminated - Nanoscale Company out of business | Sponsor / business decision |
| NCT00268463 | Oxaliplatin and Capecitabine With or Without an Hepatic Arterial Infusion With… | Phase 3 | terminated | Dec 22, 2005 | NSABP Foundation Inc | The study was terminated due to low accrual. | Enrollment / accrual |
| NCT01189227 | Combination Chemotherapy Before or After Surgery in Treating Patients With Colorectal… | Phase 3 | terminated | Aug 26, 2010 | NSABP Foundation Inc | The study was terminated due to low accrual. | Enrollment / accrual |
| NCT00006015 | Combination Chemotherapy Plus Trastuzumab in Treating Patients With Advanced, Recurrent,… | Phase 2 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | lack of sufficient accrual | Enrollment / accrual |
| NCT01528501 | Histone Deacetylases - Gastric Cancer (HDAC-GaCa-2008)(HDAC) | Phase 2 | terminated | Feb 8, 2012 | Technical University of Munich | medical/ethical reasons | Other (stated, no rule matched) |
| NCT00960427 | Studying Biomarkers in Tumor Tissue and Blood Samples From Patients Undergoing… | Phase 1 | withdrawn | Aug 17, 2009 | Barbara Ann Karmanos Cancer Institute | No surgeon available to perfrom gastroscopy | Other (stated, no rule matched) |
| NCT01466504 | Effect of Sorafenib or Regorafenib on P63 Expression and Keratinocyte Differentiation in… | — | terminated | Nov 8, 2011 | Dartmouth-Hitchcock Medical Center | Accrual did not meet expectations. Over nearly 2 years just 4 subjects were treated on study. The… | Enrollment / accrual |
| NCT00004193 | ISIS 2503 in Treating Patients With Metastatic and/or Locally Recurrent Colorectal Cancer | Phase 2 | terminated | Aug 5, 2004 | University of Alabama at Birmingham | not stated | Not stated |
| NCT00828594 | Global Study Looking at the Combination of RAD001 and Sorafenib to Treat Patients With… | Phase 1 | terminated | Jan 26, 2009 | Novartis Pharmaceuticals | not stated | Not stated |
| NCT00899002 | Biomarkers in Stored Tumor Samples From Younger Patients With Liver Cancer | — | withdrawn | May 12, 2009 | Vanderbilt-Ingram Cancer Center | slow accrual | Enrollment / accrual |
| NCT01329809 | Neoadjuvant Study of Recombinant Vaccinia Virus to Treat Metastatic Colorectal Carcinoma… | Phase 2 | terminated | Apr 6, 2011 | Jennerex Biotherapeutics | not stated | Not stated |
| NCT00253617 | Stent Placement With or Without Photodynamic Therapy Using Porfimer Sodium as Palliative… | Phase 3 | withdrawn | Nov 15, 2005 | Jonsson Comprehensive Cancer Center | not stated | Not stated |
| NCT00016029 | Comparison of Barium Enema, Computed Tomographic Colonography, and Colonoscopy in… | N/A | terminated | Jan 27, 2003 | Duke University | not stated | Not stated |
| NCT00332280 | Study to Evaluate the Clinical Benefit Response in Cancer Patients With Advanced Disease… | Phase 2 / Phase 3 | terminated | Jun 1, 2006 | Auron Healthcare GmbH | Lack of efficacy. Stopped at first interim evaluation point | Efficacy / futility |
| NCT00405561 | Study to Evaluate Progression Free Survival in Cancer Patients With Advanced Colorectal… | Phase 2 / Phase 3 | terminated | Nov 30, 2006 | Auron Healthcare GmbH | Lack of efficacy | Efficacy / futility |
| NCT00405873 | Study to Evaluate Tumour Response in Cancer Patients With Advanced Hepatocellular… | Phase 2 | terminated | Nov 30, 2006 | Auron Healthcare GmbH | Lack of efficacy | Efficacy / futility |
| NCT00662688 | Chemotherapy With or Without Dalteparin in Treating Patients With Metastatic Pancreatic…(PAM07) | Phase 3 | terminated | Apr 21, 2008 | GERCOR - Multidisciplinary Oncology Cooperative Group | recruitment prematurely stopped due to a lack of eligible patients. | Enrollment / accrual |
| NCT01786538 | Second-line FOLFOX With or Without Regorafenib in mCRC Patients Failed to First-line… | Phase 3 | withdrawn | Feb 8, 2013 | Asan Medical Center | not stated | Not stated |
| NCT00937482 | Cediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases… | Phase 1 | terminated | Jul 13, 2009 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00608595 | Celecoxib in Treating Patients With Early-Stage Rectal Cancer | N/A | terminated | Feb 6, 2008 | Vanderbilt-Ingram Cancer Center | low accrual | Enrollment / accrual |
| NCT00959946 | Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic… | Phase 1 / Phase 2 | terminated | Aug 17, 2009 | Pfizer | not stated | Not stated |
| NCT01401387 | Pancreatic Enzyme Suppletion in Pancreatic Cancer(EPC) | Phase 4 | withdrawn | Jul 25, 2011 | Foundation for Liver Research | study never started | Other (stated, no rule matched) |
| NCT00531115 | Phase II Study to Evaluate Safety and Efficacy of Cetuximab in Combination With XELOX for… | Phase 2 | terminated | Sep 18, 2007 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) | According to the study design, in the first step the number of responses was lower than the number… | Other (stated, no rule matched) |
| NCT00003851 | Gemcitabine Compared With Pancreatic Enzyme Therapy Plus Specialized Diet (Gonzalez… | N/A | terminated | Jan 27, 2003 | Columbia University | Approval lapse | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Aug 5, 2013source: clinicaltrials