Clinical trial · Interventional
Comparison of Barium Enema, Computed Tomographic Colonography, and Colonoscopy in Detecting Colon Cancer
Prospective Comparison of Air Contrast Barium Enema (ACBE), Computed Tomographic Colonography (Virtual Colonoscopy) and Colonoscopy for Evaluation of the Colon in Patients With Fecal Occult Blood
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Screening tests may help doctors detect cancer cells early and plan more effective treatment for cancer. New diagnostic procedures such as computed tomographic colonography may provide a less invasive method of identifying patients who have colon cancer. PURPOSE: Diagnostic and screening trial to compare the effectiveness of barium enema, computed tomographic colonography, and colonoscopy in detecting of colon cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| barium enema injection | Procedure | — | UNRESOLVED |
| computed tomography | Procedure | — | UNRESOLVED |
| computed tomography colonography | Procedure | — | UNRESOLVED |
| diagnostic colonoscopy | Procedure | — | UNRESOLVED |
| screening colonoscopy | Procedure | — | UNRESOLVED |
| screening questionnaire administration | Other | — | UNRESOLVED |
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS:
* One of the following must be present:
* At least 1 positive fecal occult blood test within the past 6 months
* Iron deficiency anemia, defined as:
* Hemoglobin less than 13 g/dL (males)
* Hemoglobin less than 12 g/dL (females)
* Ferritin less than 45 g/dL
* Episode of bright red blood per the rectum
* Family history of colon cancer or adenoma
* One first-degree relative diagnosed with colon cancer or adenoma at age 60 or under OR
* Two first-degree relatives diagnosed with colon cancer or adenoma at any age
* No active gastrointestinal hemorrhage, including any of the following:
* Reported or witnessed hematemesis
* Melenic stools
* Melenemesis
* Multiple episodes of hematochezia within the past 2 months
PATIENT CHARACTERISTICS:
Age:
* 18 and over
Performance status:
* Not specified
Life expectancy:
* Not specified
Hematopoietic:
* See Disease Characteristics
Hepatic:
* Not specified
Renal:
* Not specified
Cardiovascular:
* No myocardial infarction or cerebrovascular accident within the past 6 weeks
Pulmonary:
* No respiratory failure within the past 6 weeks
Other:
* No serious medical disorder (e.g., sepsis) within the past 6 weeks
* Weight less than 300 pounds
* Willing and able to undergo endoscopic or radiologic procedures
* No need for special precautions in performing endoscopic procedures (e.g., antibiotic prophylaxis or complicated anticoagulation reversal)
* No prisoners
* Not pregnant
* Negative pregnancy test
* Fertile patients must use effective contraception
PRIOR CONCURRENT THERAPY:
Biologic therapy:
* Not specified
Chemotherapy:
* Not specified
Endocrine therapy:
* Not specified
Radiotherapy:
* Not specified
Surgery:
* Not specified
Other:
* No other concurrent clinical trial participation involving drugs, medical devices, and/or biologicsReferences
Publications (0)
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