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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
1,575 stopped studies mapped to Malignant Breast Neoplasm and descendants · 90% state a reason
Over the 1,575 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00017537 | Vaccine Therapy in Treating Patients With Metastatic or Recurrent Cancer | Phase 1 | withdrawn | Jan 8, 2004 | University of Alabama at Birmingham | not stated | Not stated |
| NCT00002696 | Combination Chemotherapy in Treating Women With Stage III Breast Cancer | Phase 3 | suspended | Jan 27, 2003 | Grupo Oncologico Cooperativo del Sur | not stated | Not stated |
| NCT01543126 | IL-6 and IL-8 Level of Blood and Pleural Effusion During Chemotherapy in Metastatic… | — | terminated | Mar 2, 2012 | Fudan University | it's too slow to enroll suitable patients into this study | Enrollment / accrual |
| NCT00476827 | A Phase II Safety and Tolerability Study of Bevacizumab When Added to Single-agent… | Phase 2 | terminated | May 22, 2007 | Duke University | Slow accrual | Enrollment / accrual |
| NCT01628887 | Feasibility of a Supportive Education Program for Latina Breast Cancer Survivors | N/A | terminated | Jun 27, 2012 | City of Hope Medical Center | Proposal will not be submitted and low accrual. | Enrollment / accrual |
| NCT00041353 | Comparison of Biomarkers Based on Fine-Needle Aspiration in Women at Increased or Normal… | N/A | withdrawn | May 26, 2003 | Fox Chase Cancer Center | Study was not activated at Fox Chase Cancer Center | Other (stated, no rule matched) |
| NCT00003455 | Antineoplaston Therapy in Treating Women With Advanced Breast Cancer | Phase 2 | withdrawn | Jan 27, 2003 | Burzynski Research Institute | not stated | Not stated |
| NCT00003536 | Methotrexate With or Without Antineoplaston Therapy in Treating Postmenopausal Women With… | Phase 2 | withdrawn | Jan 27, 2003 | Burzynski Research Institute | not stated | Not stated |
| NCT00080613 | Neoadjuvant and Adjuvant Exemestane in Treating Postmenopausal Women With Locally… | Phase 2 | withdrawn | Apr 8, 2004 | Robert H. Lurie Cancer Center | not stated | Not stated |
| NCT00674557 | Exemestane With or Without ATN-224 in Treating Postmenopausal Women With Recurrent or… | Phase 2 | terminated | May 8, 2008 | Cancer Research UK | Withdrawn as the clinical development of ATN-224 was terminated by the drug company who was… | Sponsor / business decision |
| NCT00896467 | Psychological and Emotional Impact in Patients Undergoing Treatment For Metastatic Cancer… | — | terminated | May 11, 2009 | Centre Oscar Lambret | not stated | Not stated |
| NCT01614184 | Fluorescein for Sentinel Lymph Node Biopsy (SLNB) in Breast Cancer | Phase 1 / Phase 2 | withdrawn | Jun 7, 2012 | University of Utah | not stated | Not stated |
| NCT00902668 | Lovastatin in Reducing Side Effects After Radiation Therapy in Women With Breast Cancer | Phase 2 | terminated | May 15, 2009 | Virginia Commonwealth University | Slow accrual | Enrollment / accrual |
| NCT00049608 | Gemcitabine Combined With Mistletoe in Treating Patients With Advanced Solid Tumors | Phase 1 | terminated | Jan 27, 2003 | National Center for Complementary and Integrative Health (NCCIH) | Principal investigator \[PI\] has left institution. | Investigator |
| NCT00589238 | Paclitaxel, Doxorubicin, and Cyclophosphamide With Or Without Carboplatin in Treating… | Phase 2 | terminated | Jan 9, 2008 | National Cancer Centre, Singapore | not stated | Not stated |
| NCT00699101 | Using the Conture® Multi-Lumen Balloon to Deliver Accelerated Partial Breast Brachytherapy | Phase 4 | terminated | Jun 17, 2008 | SenoRx, Inc. | not stated | Not stated |
| NCT01072838 | Safety Study for Short-course Accelerated, Hypofractionated Partial Breast Radiotherapy… | Phase 2 | terminated | Feb 22, 2010 | SenoRx, Inc. | not stated | Not stated |
| NCT00869674 | GeneSearch™ Breast Lymph Node (BLN) Assay China Registration Study | Phase 3 | terminated | Mar 26, 2009 | Johnson & Johnson Medical, China | Investigational products has been suspended from the US market | Other (stated, no rule matched) |
| NCT01013506 | Phase 2, Endocrine Therapy + OSI-906 With or Without Erlotinib for Hormone-sensitive… | Phase 2 | withdrawn | Nov 13, 2009 | Vanderbilt-Ingram Cancer Center | Study was abandoned before opening to accrual. Replaced by another study. | Enrollment / accrual |
| NCT01200212 | A Randomized Study to Determine the Efficacy of a Taxane and Bevacizumab With or Without…(TABEA) | Phase 3 | terminated | Sep 13, 2010 | GBG Forschungs GmbH | A planed interim analysis shows no benefits, but higher adverse event rates for the experimental… | Safety / toxicity |
| NCT01416558 | Nab-paclitaxel in Metastatic Breast Cancer Patients Failing Solvent Based Taxane (Tiffany) | Phase 2 | terminated | Aug 15, 2011 | GBG Forschungs GmbH | Study was terminated because of extrem low recruitment | Enrollment / accrual |
| NCT01141868 | Evaluating an Internet-based Intervention for Insomnia in Breast Cancer Survivors | N/A | withdrawn | Jun 11, 2010 | Milton S. Hershey Medical Center | The study never opened due to technical upgrades that were needed for the SHUTi computer system. | Other (stated, no rule matched) |
| NCT01194427 | A Study of Vorinostat and Tamoxifen in Newly Diagnosed Breast Cancer | Phase 2 | terminated | Sep 3, 2010 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Difficulty meeting patient accrual goals | Enrollment / accrual |
| NCT01219907 | Ex Vivo-Expanded HER2-Specific T Cells and Cyclophosphamide After Vaccine Therapy in… | Phase 1 | withdrawn | Oct 13, 2010 | University of Washington | not stated | Not stated |
| NCT00691119 | Relaxation and Visualization Therapy for Breast Cancer Patients | N/A | terminated | Jun 5, 2008 | National University of Natural Medicine | Inadequate recruitment | Enrollment / accrual |
| NCT00498901 | Letrozole and Goserelin or Leuprolide in Treating Premenopausal Estrogen… | Phase 2 | terminated | Jul 11, 2007 | University of Washington | not stated | Not stated |
| NCT01383408 | Distinction Between Lung Cancer and Gynecological Cancers by Canine Scent Detection | Phase 2 | terminated | Jun 28, 2011 | Schillerhoehe Hospital | Inconsistent training status of sniffer dogs | Other (stated, no rule matched) |
| NCT00903214 | Riluzole in Women With Stage I, Stage II, or Stage IIIA Breast Cancer | Phase 1 | withdrawn | May 18, 2009 | Barbara Ann Karmanos Cancer Institute | Funding ended | Funding |
| NCT00873808 | S0307A, Long-Term Bone Quality in Women With Breast Cancer Enrolled on Clinical Trial… | — | withdrawn | Apr 2, 2009 | SWOG Cancer Research Network | lack of accrual | Enrollment / accrual |
| NCT00496379 | ZK219477 (Sagopilone) in Patients With Breast Cancer and Brain Metastases | Phase 2 | terminated | Jul 4, 2007 | Nancy Lin, MD | This study has closed to accrual early due to slow accrual. | Enrollment / accrual |
| NCT00937482 | Cediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases… | Phase 1 | terminated | Jul 13, 2009 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT01658358 | ErbB2 Positive Metastatic Breast Cancer | Phase 1 / Phase 2 | terminated | Aug 7, 2012 | China Medical University Hospital | not stated | Not stated |
| NCT00082667 | Gefitinib Followed By Surgery in Treating Women With Ductal Carcinoma In Situ of the… | Phase 2 | terminated | May 19, 2004 | Vanderbilt-Ingram Cancer Center | PI left VICC | Investigator |
| NCT00959946 | Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic… | Phase 1 / Phase 2 | terminated | Aug 17, 2009 | Pfizer | not stated | Not stated |
| NCT00431795 | Randomized Phase II Study of Epirubicin vs Caelyx in Pretreated Metastatic Breast Cancer | Phase 2 | terminated | Feb 6, 2007 | Hellenic Oncology Research Group | Due to poor accrual | Enrollment / accrual |
| NCT00440622 | Study of Gemcitabine and Herceptin Versus Xeloda and Herceptin in HER-2 (+) Metastatic… | Phase 3 | terminated | Feb 27, 2007 | Hellenic Oncology Research Group | Due to poor accrual | Enrollment / accrual |
| NCT01612728 | Treatment for Joint Pains Due to Aromatase Inhibitor Therapy in Breast Cancer(AIA) | Phase 2 | withdrawn | Jun 6, 2012 | Baylor Breast Care Center | The grant application for this project was rejected. | Other (stated, no rule matched) |
| NCT00542594 | Survey in Post-menopausal Women Followed up After Treatment With Anastrozole as Adjuvant…(ARIES) | — | terminated | Oct 11, 2007 | AstraZeneca | No results are avaialble as the study did not complete according to the protocol | Other (stated, no rule matched) |
| NCT00206414 | Arimidex/Faslodex/Iressa Study: A Trial Using Arimidex, Faslodex and Iressa in Women With… | Phase 2 | terminated | Sep 21, 2005 | Baylor Breast Care Center | Difficulty accruing subjects the study accrual was closed | Enrollment / accrual |
| NCT00206453 | Extension Neoadjuvant Taxotere: Study of the Effects of Taxotere in Patients With Breast… | Phase 2 | terminated | Sep 21, 2005 | Baylor Breast Care Center | accrual too difficult to meet | Enrollment / accrual |
| NCT00039455 | Trastuzumab and Flavopiridol in Treating Patients With Metastatic Breast Cancer | Phase 1 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00903305 | Nurse-Provided Care or Standard Care in Treating Patients With Stage I, Stage II, or… | N/A | withdrawn | May 18, 2009 | City of Hope Medical Center | not stated | Not stated |
| NCT00523809 | Allogeneic Hematopoietic Stem Cell Transplantation With Bevacizumab for Advanced Solid… | Phase 2 | terminated | Sep 3, 2007 | M.D. Anderson Cancer Center | Slow accrual. | Enrollment / accrual |
| NCT00002772 | S9623, Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating… | Phase 3 | terminated | Apr 22, 2004 | SWOG Cancer Research Network | poor accrual | Enrollment / accrual |
| NCT00005983 | S9927 Radiation Therapy After Surgery, Chemotherapy, and/or Hormone Therapy in Stage II… | Phase 3 | terminated | Jan 27, 2003 | SWOG Cancer Research Network | due to lack of accrual | Enrollment / accrual |
| NCT00025493 | S0029 Docetaxel in Treating Older Women With Metastatic Breast Cancer | Phase 2 | terminated | Jan 27, 2003 | SWOG Cancer Research Network | poor accrual | Enrollment / accrual |
| NCT00227474 | S0348 Vaccine Therapy in Treating Patients With Stage IIIB or Stage IV Breast Cancer in… | Phase 2 | withdrawn | Sep 28, 2005 | SWOG Cancer Research Network | SWOG has decided to not pursue this trial | Other (stated, no rule matched) |
| NCT00674414 | Trastuzumab With or Without Everolimus in Treating Women With Breast Cancer That Can Be… | Phase 2 | terminated | May 7, 2008 | UNICANCER | IDMC decision due to accrual issue (82 pts accrued / 120 expected) | Enrollment / accrual |
| NCT00016276 | Combination Chemotherapy, Surgery, and Radiation Therapy With or Without Dexrazoxane and… | Phase 3 | terminated | Sep 4, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00095888 | 3-AP and Gemcitabine in Treating Patients With Refractory Metastatic Breast Cancer | Phase 2 | terminated | Nov 9, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Aug 5, 2013source: clinicaltrials