Clinical trial · Interventional
Distinction Between Lung Cancer and Gynecological Cancers by Canine Scent Detection
Distinction Between Lung Cancer and Gynecological Cancers by Exhalation Analysis and Canine Scent Detection
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Inconsistent training status of sniffer dogs
Summary
Brief summary (as posted)
Previous studies have shown that specially trained sniffer dogs are capable to discriminate breath samples of patients with lung cancer and healthy individuals. So far it is not known whether this differentiation is specific for lung cancer or just identifies any form of (solid) tumor. Therefore, the dog's ability to differentiate between lung cancer, breast cancer and ovarian cancer is tested.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Ovarian Cancer | Malignant Ovarian Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| exhalation analysis of breath sample | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- SHAM_COMPARATOR
- label
- healthy individual
- description
- healthy individual with no lung disease and no history of cancer including lung cancer
- interventionNames
- Other: exhalation analysis of breath sample
- type
- EXPERIMENTAL
- label
- lung cancer
- description
- patients with histologically confirmed lung cancer, but no history of other cancer
- interventionNames
- Other: exhalation analysis of breath sample
- type
- EXPERIMENTAL
- label
- breast cancer
- description
- patients with histologically confirmed breast cancer, but no history of other cancer
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * histologically confirmed lung or breast or ovarian cancer Exclusion Criteria: * other cancers * previous medical intervention within the last 14 days before gathering of the breath sample
References
Publications (2)
- BACKGROUNDBoedeker E, Friedel G, Walles T. Sniffer dogs as part of a bimodal bionic research approach to develop a lung cancer screening. Interact Cardiovasc Thorac Surg. 2012 May;14(5):511-5. doi: 10.1093/icvts/ivr070. Epub 2012 Feb 17. PMID 22345057
- BACKGROUNDEhmann R, Boedeker E, Friedrich U, Sagert J, Dippon J, Friedel G, Walles T. Canine scent detection in the diagnosis of lung cancer: revisiting a puzzling phenomenon. Eur Respir J. 2012 Mar;39(3):669-76. doi: 10.1183/09031936.00051711. Epub 2011 Aug 18. PMID 21852337