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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
109 stopped studies mapped to Childhood Malignant Neoplasm and descendants · 87% state a reason
Over the 109 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computed
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT04244955 | Observational Study Evaluating the Psychic Impact of the Diagnostic Announcement and Care…(IPSYLON) | — | terminated | Jan 28, 2020 | Centre Leon Berard | Investigator's decision | Investigator |
| NCT05051800 | Enhancing Coping and Communication in Children With Cancer and Their Parents(ALSF) | N/A | terminated | Sep 21, 2021 | Vanderbilt University | Recruitment of participants was interrupted by the COVID-19 pandemic and the funding for the study… | COVID-19 / pandemic |
| NCT03806556 | A Pediatric Trial Using Tranexamic Acid in Thrombocytopenia | Phase 1 / Phase 2 | terminated | Jan 16, 2019 | Meghan McCormick | Low accrual rate, strategic reasons | Enrollment / accrual |
| NCT00439296 | ABT-751 With Chemotherapy for Relapsed Pediatric ALL | Phase 1 / Phase 2 | terminated | Feb 23, 2007 | Therapeutic Advances in Childhood Leukemia Consortium | The study was stopped due to poor accrual and lack of funding. | Enrollment / accrual |
| NCT02255461 | Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or… | Phase 1 | terminated | Oct 2, 2014 | Pediatric Brain Tumor Consortium | Data for the primary objectives is complete and the MTD identified in Stratum II. | Other (stated, no rule matched) |
| NCT00176930 | Stem Cell Transplant for Hematological Malignancy | N/A | terminated | Sep 15, 2005 | Masonic Cancer Center, University of Minnesota | replaced by another study ; Trial re-written as MT2015-29 | Other (stated, no rule matched) |
| NCT01987596 | Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After… | Phase 3 | terminated | Nov 19, 2013 | Barbara Ann Karmanos Cancer Institute | not stated | Not stated |
| NCT00633061 | Identification and Treatment of Clinically Silent Catheter-Related Deep Vein Thrombosis…(DVT) | Phase 2 | terminated | Mar 11, 2008 | University of Texas Southwestern Medical Center | Futility; unable to complete screening due to clinical practice change | Efficacy / futility |
| NCT03556930 | Simulated Radiotherapy Treatment Assisted With Pediatric Radiation Oncology With Movie… | Early Phase 1 | withdrawn | Jun 14, 2018 | University of Texas Southwestern Medical Center | Project was never initiated. | Other (stated, no rule matched) |
| NCT04044378 | Famitinib Plus Camrelizumab & Famitinib Alone & Famitinib Plus Ifosfamide in Advanced… | Phase 1 / Phase 2 | withdrawn | Aug 5, 2019 | Peking University People's Hospital | toxicity | Safety / toxicity |
| NCT03127254 | Can Making Video Narratives Benefit Adolescents With Cancer | N/A | withdrawn | Apr 25, 2017 | Case Comprehensive Cancer Center | Research cancelled | Other (stated, no rule matched) |
| NCT02082626 | Study of Eribulin in Children With Cancer to Determine Safety(ERIBULIN) | Phase 1 | terminated | Mar 10, 2014 | University of Oklahoma | Competing study opened | Other (stated, no rule matched) |
| NCT02819804 | Nivolumab and Dasatinib in Treating Patients With Relapsed or Refractory Philadelphia… | Phase 1 | terminated | Jun 30, 2016 | Northwestern University | Due to funding and accrual issues | Enrollment / accrual |
| NCT02684071 | Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive… | Phase 2 | terminated | Feb 17, 2016 | Nicklaus Children's Hospital f/k/a Miami Children's Hospital | Lack of additional funding; patients (3) no longer receiving intervention. | Funding |
| NCT03334162 | Playful Sensorimotor Training in Pediatric Brain Tumor Patients(RESET) | N/A | suspended | Nov 7, 2017 | University of Basel | study temporarily paused due to an Amendment request | Other (stated, no rule matched) |
| NCT02989675 | SugarFACT - Sugar Requirements For African Children Trial | N/A | terminated | Dec 12, 2016 | Helena Hildenwall | not stated | Not stated |
| NCT03003273 | Early Stoppage Versus Continuation of Antimicrobial Therapy in Low Risk Pediatric Cancer…(DALFEN) | Phase 3 | terminated | Dec 28, 2016 | All India Institute of Medical Sciences | poor accrual | Enrollment / accrual |
| NCT02587871 | Donor Cellular Therapy After Cytarabine in Treating Patients With Intermediate-Risk Acute… | Phase 2 | withdrawn | Oct 27, 2015 | University of Southern California | PI decided not to pursue study | Other (stated, no rule matched) |
| NCT02728700 | Sirolimus and Mycophenolate Mofetil in Preventing GVHD in Patients With Hematologic… | Phase 1 | terminated | Apr 5, 2016 | Stanford University | Accrual factor | Enrollment / accrual |
| NCT00900445 | Studying Body Mass Index in Younger Patients Who Are Receiving Treatment for High-Risk… | — | withdrawn | May 12, 2009 | Children's Oncology Group | not stated | Not stated |
| NCT01453465 | Biomarker Study in Samples From Patients With Malignant Rhabdoid Tumor of the Kidney or… | — | withdrawn | Oct 17, 2011 | Children's Oncology Group | not stated | Not stated |
| NCT01642095 | Studying Biomarkers in Samples From Younger Patients With Kidney Cancer | — | withdrawn | Jul 17, 2012 | Children's Oncology Group | not stated | Not stated |
| NCT02011126 | Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors | Phase 2 | withdrawn | Dec 13, 2013 | Children's Oncology Group | IND no longer available. | Other (stated, no rule matched) |
| NCT01801046 | Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia | Phase 1 | terminated | Feb 28, 2013 | University of Southern California | Insufficient Accrual | Enrollment / accrual |
| NCT00354107 | Ifosfamide, Carboplatin, Etoposide, and SGN-30 in Treating Young Patients With Recurrent… | Phase 1 / Phase 2 | terminated | Jul 20, 2006 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00852709 | Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated…(POE07-01) | Phase 1 | terminated | Feb 27, 2009 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Lack of accrual | Enrollment / accrual |
| NCT02259348 | Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following… | Phase 2 | terminated | Oct 8, 2014 | St. Jude Children's Research Hospital | Investigator's decision. | Investigator |
| NCT02564536 | Pacritinib in Combination With Low Dose Decitabine in Intermediate-High Risk… | Phase 1 | withdrawn | Sep 30, 2015 | Washington University School of Medicine | Lack of funding following full FDA clinical hold | Funding |
| NCT02791919 | Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children,… | Phase 1 | withdrawn | Jun 7, 2016 | National Cancer Institute (NCI) | Other - Protocol moved to Disapproved | Other (stated, no rule matched) |
| NCT02194452 | Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young… | N/A | withdrawn | Jul 18, 2014 | Sue O'Dorisio | not stated | Not stated |
| NCT02227108 | Study in Pediatrics With Relapsed or Refractory Pediatric Acute Lymphoblastic Leukemia… | Phase 2 | terminated | Aug 27, 2014 | MedImmune LLC | The study was terminated prior to a planned interim analysis based on lack of required efficacy in… | Efficacy / futility |
| NCT02175745 | 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or… | N/A | terminated | Jun 26, 2014 | Erik Mittra | Re-evaluate indication with the referring physicians | Other (stated, no rule matched) |
| NCT01621477 | T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell… | Phase 2 | terminated | Jun 18, 2012 | St. Jude Children's Research Hospital | Study was terminated in August 2016 due to replacement by a new study. | Other (stated, no rule matched) |
| NCT00052598 | Therapeutic Allogeneic Lymphocytes and Aldesleukin in Treating Patients With High-Risk or… | Phase 1 / Phase 2 | terminated | Jan 27, 2003 | Fred Hutchinson Cancer Center | not stated | Not stated |
| NCT02130934 | Cardiac 3D MRI in Pediatric Cancer Patients | — | withdrawn | May 6, 2014 | Majd Makhoul | Slow accrual | Enrollment / accrual |
| NCT00767234 | Permission to Collect Blood Over Time for Research | — | terminated | Oct 7, 2008 | Stanford University | Accrual issues - Low Accrual | Enrollment / accrual |
| NCT02031965 | Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade… | Phase 1 | terminated | Jan 9, 2014 | Pediatric Brain Tumor Consortium | not stated | Not stated |
| NCT02000986 | Dietary and Exercise Interventions in Preventing Cardiovascular Disease in Younger… | N/A | withdrawn | Dec 4, 2013 | Virginia Commonwealth University | Slow accrual | Enrollment / accrual |
| NCT00669890 | Allogenic Stem Cell Transplantation in Patients With High Risk CD33+ AML/MDS/JMML(High Risk) | Phase 1 | terminated | May 1, 2008 | New York Medical College | PI left institution | Investigator |
| NCT01100658 | Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors | N/A | terminated | Apr 9, 2010 | University of Minnesota | Due to slow accrual | Enrollment / accrual |
| NCT01795430 | Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed… | N/A | withdrawn | Feb 20, 2013 | City of Hope Medical Center | No participants enrolled. | Enrollment / accrual |
| NCT01088763 | Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or… | Phase 1 | terminated | Mar 17, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01828502 | Cotinine Feedback as an Intervention to Change Parental/Caregiver Smoking Behavior Around… | Phase 2 | withdrawn | Apr 10, 2013 | University of South Florida | The study was closed due to poor accrual. No patients were enrolled. | Enrollment / accrual |
| NCT00941928 | Haploidentical Natural Killer (NK) Cells With Epratuzumab for Relapsed Acute… | Phase 2 | terminated | Jul 20, 2009 | M.D. Anderson Cancer Center | Slow accrual | Enrollment / accrual |
| NCT00933985 | Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane… | Phase 1 | terminated | Jul 8, 2009 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01655875 | AMD3100 for Sensitizing in Allogeneic Blood or Marrow Transplant for Chemotherapy…(BMTAMD3100) | Phase 1 | terminated | Aug 2, 2012 | Emory University | lack of patient enrollment | Enrollment / accrual |
| NCT00101205 | Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or… | Phase 1 | terminated | Jan 10, 2005 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00058461 | Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or… | Phase 2 | terminated | Apr 9, 2003 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01896440 | Heart Safety Study of Ondansetron in Children Receiving Chemotherapy | Phase 4 | withdrawn | Jul 11, 2013 | University of Oklahoma | FDA did not approve | Other (stated, no rule matched) |
| NCT01697514 | A Study of LY2940680 in Pediatric Medulloblastoma or Rhabdomyosarcoma | Phase 1 | withdrawn | Oct 2, 2012 | Eli Lilly and Company | Trial stopped early for poor accrual. | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Oct 13, 2021source: clinicaltrials