Clinical trial · Observational
Cardiac 3D MRI in Pediatric Cancer Patients
Left Ventricular Strain Assessment Using 3d Cardiac Magnetic Resonance Technique In Asymptomatic Pediatric Patients Who Received Cardiotoxic Chemotherapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Slow accrual
Summary
Brief summary (as posted)
This is a non-randomized prospective pilot study in a single academic center with historic controls. This study will compare Cardiac Magnetic Resonance Images (MRI) of patients who have undergone childhood cancer treatment that has cardio-toxic effects to historic controls. The ultimate goal of this study is to develop a safe and effective method for early diagnosis of heart problems in children who are receiving chemotherapy treatments that may be toxic to the heart.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Childhood Cancer | Childhood Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cardiac 3D MRI | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- childhood cancer survivors
- description
- Cardiac 3D MRI
- interventionNames
- Procedure: Cardiac 3D MRI
Primary outcomes (1)
- measure
- Ventricular Function Measurement
- timeFrame
- Up to 2 years
- description
- Quantify ventricular functional measurements including strain patterns and measurements using offline processing software that Dr. Fornwalt lab has.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 8 Years
- Maximum age
- 26 Years
Show eligibility criteria text
Inclusion Criteria: * Childhood cancer treatment which has been completed * Received anthracyclines as part of childhood cancer treatment, at least 150 mg/m2 as cumulative dose * normal left ventricular systolic and diastolic functions on echocardiogram Exclusion Criteria: * Ongoing cancer treatment * Pregnancy * Inability to undergo a cardiac MRI * Abnormal ventricular systolic or diastolic function on echocardiogram
References
Publications (0)
Data not yet available