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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
109 stopped studies mapped to Childhood Malignant Neoplasm and descendants · 87% state a reason
Over the 109 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computed
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT07052994 | A Phase Ia/Ib Trial of Revumenib Combined With Cytarabine, Daunorubicin, and Gemtuzumab… | Phase 1 | withdrawn | Jul 8, 2025 | M.D. Anderson Cancer Center | PI requested | Other (stated, no rule matched) |
| NCT06421155 | Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia | N/A | suspended | May 20, 2024 | Case Comprehensive Cancer Center | Voluntary hold by PI | Other (stated, no rule matched) |
| NCT06620302 | Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment… | Phase 1 / Phase 2 | suspended | Oct 1, 2024 | Children's Oncology Group | Unacceptable Toxicity | Safety / toxicity |
| NCT04539366 | Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children,… | Phase 1 | suspended | Sep 7, 2020 | National Cancer Institute (NCI) | Other - review of safety data | Safety / toxicity |
| NCT05454163 | Post-radiotherapy Rhinosinusitis in Children(PRRSC) | — | withdrawn | Jul 12, 2022 | University Hospital, Lille | COVID | COVID-19 / pandemic |
| NCT01552434 | Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in… | Phase 1 | terminated | Mar 13, 2012 | M.D. Anderson Cancer Center | \< 75 % participation | Other (stated, no rule matched) |
| NCT02664389 | Targeted Next-generation Sequencing Panel for Identification of Germline Mutations in…(PANEL) | N/A | terminated | Jan 27, 2016 | University Hospital, Rouen | Difficulty in enrolling patients | Enrollment / accrual |
| NCT07498465 | A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After… | Phase 1 | withdrawn | Mar 27, 2026 | Children's Oncology Group | Other - Protocol moved to Withdrawn | Other (stated, no rule matched) |
| NCT05132673 | Cardiac Autonomic Dysfunction in Childhood Cancer Survivors | — | withdrawn | Nov 24, 2021 | St. Jude Children's Research Hospital | This protocol was placed on hold in January 2023 as funding was not received to support study… | Enrollment / accrual |
| NCT07222358 | Multi-component Remote Assessment in Adult Survivors Using a Connected Technology… | — | withdrawn | Oct 29, 2025 | St. Jude Children's Research Hospital | After PI and vendor discussions, the decision was made not to proceed with the contract. The… | Other (stated, no rule matched) |
| NCT05181904 | Gastric Content Ultrasound Monitoring Prior to Extubation in Critically Ill Children(GastrExtub) | — | terminated | Jan 10, 2022 | Hospices Civils de Lyon | Patient enrollment difficulties | Enrollment / accrual |
| NCT04049383 | CAR-20/19-T Cells in Patients With Relapsed/Refractory B Cell ALL(CAR-20/19-T) | Phase 1 | terminated | Aug 8, 2019 | Medical College of Wisconsin | Low accrual | Enrollment / accrual |
| NCT03904862 | Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma… | Phase 1 / Phase 2 | terminated | Apr 5, 2019 | Pediatric Brain Tumor Consortium | The decision to permanently close PBTC-053 was made following communication from the NCI that the… | Other (stated, no rule matched) |
| NCT04678336 | CD123 Redirected T Cells for AML in Pediatric Subjects | Phase 1 | terminated | Dec 21, 2020 | University of Pennsylvania | Administrative reasons | Other (stated, no rule matched) |
| NCT04036045 | Approaches to Identify Early Biomarkers and Pathogenesis of Anthracycline Cardiotoxicity | — | withdrawn | Jul 29, 2019 | Connecticut Children's Medical Center | No funding, no participation | Funding |
| NCT06639958 | A Study of Different Programs to Help ALL Patients With Taking Maintenance Medicine at… | N/A | suspended | Oct 15, 2024 | Children's Oncology Group | All potential pilot phase pts have been enrolled. | Enrollment / accrual |
| NCT05000905 | Improving Cognition and Behavior in Pediatric Cancer Survivors Using a Novel Mindful… | N/A | withdrawn | Aug 11, 2021 | University of California, San Francisco | Slow accrual | Enrollment / accrual |
| NCT04239092 | 9-ING-41 in Pediatric Patients With Refractory Malignancies. | Phase 1 | terminated | Jan 23, 2020 | Actuate Therapeutics Inc. | The decision to conclude study was made to optimize the clinical study design and protocol to… | Safety / toxicity |
| NCT06013904 | Difficult PIV Placement in the Pediatric ED | N/A | withdrawn | Aug 28, 2023 | University of Texas at Austin | The logistics of the study made it too challenging to conduct within a pediatric setting. | Other (stated, no rule matched) |
| NCT03537599 | Daratumumab and Donor Lymphocyte Infusion in Treating Participants With Relapsed Acute… | Phase 1 / Phase 2 | terminated | May 25, 2018 | Sumithira Vasu | Poor acccrual | Other (stated, no rule matched) |
| NCT05781672 | Prediction of Delayed Toxic Cardiomyopathy in Children(SpeckleAnthra2) | N/A | terminated | Mar 23, 2023 | University Hospital, Montpellier | Analyses will be performed with data from included patients until the end of the inclusion period.… | Other (stated, no rule matched) |
| NCT06023368 | Reducing Port Access Pain and Clinic Wait Time: An Evaluation of EMLA Cream Versus nüm™… | Phase 4 | withdrawn | Sep 5, 2023 | Marianne Hutti | Administrative burden | Other (stated, no rule matched) |
| NCT04523623 | Pain Control Differences Between Oxycodone and Ibuprofen in Children With Isolated… | N/A | withdrawn | Aug 21, 2020 | Washington University School of Medicine | Project canceled for other reason , describe: - Lack of enrollment Project canceled - lack of… | Enrollment / accrual |
| NCT04996745 | Taking POSNA's OrthoKids to the People | N/A | withdrawn | Aug 9, 2021 | Louisiana State University Health Sciences Center in New Orleans | Submitted in error | Other (stated, no rule matched) |
| NCT05569512 | Uproleselan With Pre-Transplant Conditioning in Hematopoietic Stem Cell Transplantation… | Phase 1 | terminated | Oct 6, 2022 | Malika Kapadia | On 7/26/24 the Sponsor-Investigator was notified GlycoMimetics was terminating contracting for… | Investigator |
| NCT05112458 | Cope 360 App for Caregivers of Children With Cancer | N/A | withdrawn | Nov 8, 2021 | Indiana University | Grant funding ended prior to enrolling any participants. | Enrollment / accrual |
| NCT05622591 | ELU001 in Pediatric Subjects Who Have Relapsed and/or Refractory CBFA2T3-GLIS2-positive…(Pediatric AML) | Phase 1 | withdrawn | Nov 18, 2022 | Elucida Oncology | Lack of Funding - no safety issue with Drug; Company Permanently Closed | Safety / toxicity |
| NCT06335745 | PediCARE Health Equity Intervention in High-Risk Neuroblastoma | N/A | withdrawn | Mar 28, 2024 | Dana-Farber Cancer Institute | Study halted prematurely, prior to enrollment of first participant | Enrollment / accrual |
| NCT01034670 | Advanced Gastrointestinal Endoscopic Imaging | N/A | terminated | Dec 17, 2009 | Stanford University | Change in personnel and cessation of funding | Funding |
| NCT04315883 | Yttrium-90 (TARE-Y90) in Children, Adolescents, and Young Adults With Liver Tumors | — | terminated | Mar 20, 2020 | Nemours Children's Clinic | PI left organization and discontinued study | Investigator |
| NCT02624388 | Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)(UVA-Gen001) | Phase 2 | terminated | Dec 8, 2015 | University of Virginia | Poor enrollment | Enrollment / accrual |
| NCT04341311 | Phase I Study of Marizomib + Panobinostat for Children With DIPG(DIPG) | Phase 1 | terminated | Apr 10, 2020 | Dana-Farber Cancer Institute | Withdrawal of support from BMS | Other (stated, no rule matched) |
| NCT04785547 | ALL SCTped 2012 FORUM Add-on Study Blina Post HSCT | Phase 2 | terminated | Mar 8, 2021 | Prof. Christina Peters | Terminated by Amgen Limited | Other (stated, no rule matched) |
| NCT03866707 | Epigenetic and Metabolomic Changes in Childhood Cancer Survivors | — | terminated | Mar 7, 2019 | Wake Forest University Health Sciences | PI left institution, study will not resume and considered complete | Investigator |
| NCT00540995 | Busulfan, Etoposide, and Intensity-Modulated Radiation Therapy Followed By Donor Stem… | Phase 1 / Phase 2 | terminated | Oct 8, 2007 | City of Hope Medical Center | Unable to safely escalate to TMLI doses that were hypothesized to be effective and less toxic than… | Enrollment / accrual |
| NCT04167618 | 177Lu-DTPA-Omburtamab Radioimmunotherapy for Recurrent or Refractory Medulloblastoma | Phase 1 / Phase 2 | terminated | Nov 19, 2019 | Y-mAbs Therapeutics | Business priorities | Sponsor / business decision |
| NCT02536183 | A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric… | Phase 1 | terminated | Aug 31, 2015 | AeRang Kim | low accrual | Enrollment / accrual |
| NCT05645133 | QPlus Pediatric Reference Interval | — | terminated | Dec 9, 2022 | HemoSonics LLC | PI relocated to another institution | Other (stated, no rule matched) |
| NCT05077423 | A Phase 1 Trial of CD33xCD3 BsAb in Pediatric Patients With Relapsed or Refractory Acute… | Phase 1 | terminated | Oct 14, 2021 | Y-mAbs Therapeutics | Study terminated due to business priorities | Sponsor / business decision |
| NCT03705507 | International Trial of Selumetinib in Combination With Dexamethasone for the Treatment of…(SeluDex) | Phase 1 / Phase 2 | terminated | Oct 15, 2018 | University of Birmingham | Poor recruitment, due to a change in the standard of care for this patient population with the use… | Enrollment / accrual |
| NCT03043430 | Intranasal Ketamine for Anxiolysis in Pediatric Emergency Department Patients | Phase 4 | terminated | Feb 6, 2017 | Brooke Army Medical Center | Research manpower shortage | Other (stated, no rule matched) |
| NCT04311866 | Femoral Pediatric Fractures. Walking Spica Cast vs Synthetic Pants | N/A | withdrawn | Mar 17, 2020 | Universidad Autonoma de Nuevo Leon | Lack of material for treatment of the patients | Other (stated, no rule matched) |
| NCT01028716 | Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic… | Phase 2 | terminated | Dec 9, 2009 | Fred Hutchinson Cancer Center | The study experienced lower accrual rates after the onset of COVID. Upon review of the collected… | COVID-19 / pandemic |
| NCT00119366 | Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and… | Phase 2 | terminated | Jul 13, 2005 | Fred Hutchinson Cancer Center | Funding ended before target accrual was reached; participants are no longer being examined or… | Enrollment / accrual |
| NCT04719416 | Relaxation Therapy in Pediatric Oncology | N/A | withdrawn | Jan 22, 2021 | Geisinger Clinic | Other projects and needs of study personnel | Other (stated, no rule matched) |
| NCT04807478 | Safety of Omegaven in Pediatric Patients With Parenteral Nutrition-Associated Cholestasis… | — | withdrawn | Mar 19, 2021 | Fresenius Kabi | New study protocol under development | Other (stated, no rule matched) |
| NCT01640301 | Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid… | Phase 1 / Phase 2 | terminated | Jul 13, 2012 | Fred Hutchinson Cancer Center | Terminated due to slow accrual. | Enrollment / accrual |
| NCT01177540 | Efficacy and Safety of Decitabine as Epigenetic Priming With Induction Chemotherapy in… | Phase 2 | terminated | Aug 9, 2010 | Eisai Inc. | The study was terminated early due to enrollment difficulties and the futility of observing… | Efficacy / futility |
| NCT04326439 | AflacLL1901 (CHOA-AML) | Phase 2 | terminated | Mar 30, 2020 | Emory University | Due to unforeseen circumstances, the study team was limited in enrolling patients on this trial;… | Enrollment / accrual |
| NCT04831827 | Promoting Equity for Cancer Screening and Follow-up | N/A | withdrawn | Apr 5, 2021 | Mayo Clinic | Insufficient study resources and change in practice. | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 4 days agoSource updated Sep 23, 2026source: clinicaltrials