Clinical trial · Observational
Studying Biomarkers in Samples From Younger Patients With Kidney Cancer
Focal Adhesion Kinase Expression in Pediatric Renal Tumors
NCT01642095CI-TRIAL-00034163withdrawnClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This laboratory study is looking into biomarkers in samples from younger patients with kidney cancer. Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors find better ways to treat cancer.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Childhood Kidney Neoplasm | Childhood Kidney Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Clear Cell Renal Cell Carcinoma | Clear Cell Renal Cell Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Congenital Mesoblastic Nephroma | Congenital Mesoblastic Nephroma | ONTOLOGY_EXACT | 0.98 |
| Rhabdoid Tumor of the Kidney | Rhabdoid Tumor of the Kidney | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laboratory Biomarker Analysis | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Basic science (FAK expression)
- description
- Archived tumor tissue samples are analyzed for FAK expression by IHC. IHC staining is compared in normal renal tissue, Wilms tumor (routine and anaplastic), malignant rhabdoid tumor of the kidney, clear cell sarcoma of the kidney, and mesoblastic nephroma.
- interventionNames
- Other: Laboratory Biomarker Analysis
Primary outcomes (1)
- measure
- FAK expression in pediatric renal tumors
- timeFrame
- Baseline
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Formalin-fixed, paraffin-embedded tissue samples from patients diagnosed with the following renal tumors: * Anaplastic Wilms tumor * Malignant rhabdoid tumor of the kidney * Clear cell sarcoma of the kidney * Mesoblastic nephroma
References
Publications (0)
Data not yet available
No reference posted for this study.