Clinical trial · Observational
Gastric Content Ultrasound Monitoring Prior to Extubation in Critically Ill Children
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Patient enrollment difficulties
Summary
Brief summary (as posted)
Nearly half of critically ill children are intubated and enterally fed according to recent guidelines. However, no evidence-based recommendation are available regarding fasting times prior to extubation. When an extubation is planned, children do not always present with normal neurological status yet, and are at risk of vomiting and aspiration. Extubation may also fail and require re-intubation with similar risks. Thus, pre-operative fasting guidelines are often transposed to the paediatric critical care setting, aiming for an empty stomach at extubation, with perceived decreased risks of aspiration. However, the gastric and gut motility pathophysiology is significantly different in critically ill children (frequent gastroparesis, liquid continuous feeding, etc.) compared to planned surgery children. The extrapolation of practice validated in the latter population may be inadequate. The stomach may be empty more or less rapidly than expected, leading to unnecessary prolonged fasting times or inappropriately short fasting times respectively. Gastric ultrasounding monitoring may help assessing gastric content prior to extubation. Investigators hypothesise gastric content clearance may be different in critically ill children prior to extubation, compared to pre-operative paediatric guidelines for elective surgery.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Aspiration | — | UNRESOLVED | — |
| Fasting | — | UNRESOLVED | — |
| Pediatric ALL | Childhood Acute Lymphoblastic Leukemia | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Gastric ultrasound | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Critically ill children ready for extubation
- description
- Children admitted to a paediatric intensive care unit, invasively ventilated and intubated, enterally fed and presenting with a clinical condition allowing for extubation. 45 children will be included.
- interventionNames
- Other: Gastric ultrasound
Primary outcomes (1)
- measure
- Percentage of critically ill children presenting with a full stomach 6 hours after enteral feeding interruption for planned extubation
- timeFrame
- 12 hours following the inclusion
- description
- Percentage of critically ill children presenting with a full stomach (according to PERLAS criteria) 6 hours after enteral feeding interruption for planned extubation. Gastric emptiness is assessed with gastric ultrasounding, depicting gastric content (empty versus full). Antral diameter will also be measured and gastric volume will be calculated to allow classifying gastric content according to PERLAS criteria.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 0 Years
- Maximum age
- 17 Years
Show eligibility criteria text
Inclusion Criteria: * 0 to 17 year old children admitted to pediatric intensive care unit * intubated (oral or nasal tracheal tube) * gastric enteral feeding affording at least 25% of the nutritional target (estimated with Schofield equations) * No opposition from one of the 2 parents (or legal representatives) Exclusion Criteria: * anatomical anomaly of the stomach location (e.g. post surgery) * Difficult access to perform gastric ultra-sounding (drains, plasters, dressings etc.) * mobilization to right lateral decubitus at risk
References
Publications (0)
Data not yet available