Publication
High expression of HEF1 predicts a poorer prognosis of hepatocellular carcinoma: A retrospective study.
Authors not recorded
Mol Clin Oncol2016PMID 26893853PMC4733949stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerHepatocellular Carcinomacivic_curation1.00
- geneNEDD9civic_curation1.00
- variantNEDD9 EXPRESSIONcivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26893853
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| NEDD9 EXPRESSION1 | ||||||||
| (prognostic) | Hepatocellular Carcinoma | Prognostic | B | Supports Poor Outcome | 3 | accepted | EID1059IHC was performed in 123 hepatocellular carcinoma tissues and their adjacent normal liver tissues for protein expression of HEF1 (NEDD9). Overexpression of HEF1 protein was observed in HCC tissue when… (full text at CIViC) PMID 26893853 · Li et al., 2016 · Open in CIViC | civic |