Variant · Expression
EPOR Overexpression
CI-VAR-00003188Explore in graph →CIViC 2588
Curated evidence
Evidence by cancer (3 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 25207766
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like1 | ||||||||
| EPOR Overexpression | (diagnostic) | Diagnostic | A | Supports Positive | 3 | submitted | EID7023The study showed that the EPOR gene rearrangements with immunoglobulin loci are associated with Ph-like molecular subtype of B-ALL, characterized by a gene-expression profile similar to that of the BC… (full text at CIViC) PMID 25207766 · Roberts et al., 2014 · Open in CIViC | civic |
| Childhood B-cell Acute Lymphoblastic Leukemia2unmapped disease | ||||||||
| EPOR Overexpression | (prognostic) | Prognostic | C | Supports Poor Outcome | 3 | submitted | EID7205The manuscripts describes a small case series (6 patients) with the t(14;19)(q32;p13.1) involving the EPOR locus in 19p13.1 and the IGH locus in 14q32, which is predicted to result in EPOR overexpress… | |
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available