Publication
Acute myeloid leukaemia (AML) with t(6;9)(p23;q34) is associated with poor outcome in childhood AML regardless of FLT3-ITD status: a report from the Children's Oncology Group.
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- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
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Linked entities
Linked entities (2)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 2
- geneNUP214civic_curation1.00
- variantNUP214 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 24661089
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| NUP214 Fusion2 | ||||||||
| (diagnostic) | Acute Myeloid Leukemia With T(6;9) (p23;q34.1)UNRESOLVED | Diagnostic | B | Supports Positive | 4 | accepted | EID12125This study gathered diagnostic and prognostic data from pediatric AML patients enrolled in Children’s Oncology Group trials between 1988 and 2010. In total 2839 patients had karyotype data available, … (full text at CIViC) PMID 24661089 · Tarlock et al., 2014 · Open in CIViC | civic |
| (prognostic) | Acute Myeloid Leukemia With T(6;9) (p23;q34.1)UNRESOLVED | Prognostic | B | Supports Poor Outcome | 4 | submitted | EID12126This study gathered prognostic data from pediatric AML patients enrolled in Children’s Oncology Group trials between 1988 and 2010. In total 2839 patients had karyotype data available and 48 patients … (full text at CIViC) PMID 24661089 · Tarlock et al., 2014 · Open in CIViC | civic |