NUP214 Fusion

CI-VAR-00001424Explore in graph →CIViC 5010

Curated evidence

Evidence by cancer (5 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–5 of 5 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Acute Myeloid Leukemia With T(6;9) (p23;q34.1)5unmapped disease
DEK::NUP214 Fusion	(diagnostic)	Diagnostic	B	Supports Positive	4	accepted	EID12123 This retrospective study from five independent study sites gathered diagnostic and prognostic data regarding the t(6;9)(p23;q34), known to result in a DEK::NUP214 fusion. Data from 20 different treatm… (full text at CIViC) PMID 16628187 · Slovak et al., 2006 · Open in CIViC	civic
DEK::NUP214 Fusion	(prognostic)	Prognostic	B	Supports Poor Outcome	4	submitted	EID12124 This retrospective study gathered diagnostic and prognostic data for acute myeloid leukemia (AML) with the t(6;9)(p23;q34), known to result in a DEK::NUP214 fusion from 20 different treatment protocol… (full text at CIViC) PMID 16628187 · Slovak et al., 2006 · Open in CIViC

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.