Publication
Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (5)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 5
- cancerAlveolar Rhabdomyosarcomacivic_curation1.00
- cancerRhabdomyosarcomacbioportal_study1.00
- geneFOXO1civic_curation1.00
- variantFOXO1 Fusioncivic_curation1.00
- variantFOXO1 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 24436047
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| FOXO1 Fusion1 | ||||||||
| (diagnostic) | Alveolar Rhabdomyosarcoma | Diagnostic | B | Supports Positive | 4 | accepted | EID11684In this study, a total of 147 rhabdomyosarcomas/normal pairs were analyzed, 44 by whole genome sequencing and 103 tumors by whole exome sequencing. 50 cases classified as alveolar rhabdomyosarcoma his… (full text at CIViC) PMID 24436047 · Shern et al., 2014 · Open in CIViC | civic |
| FOXO1 Fusion1 | ||||||||
| (diagnostic) | Alveolar Rhabdomyosarcoma | Diagnostic | B | Supports Positive | 4 | accepted | EID11685In this study, a total of 147 rhabdomyosarcomas/normal pairs were analyzed, 44 by whole genome sequencing and 103 tumors by whole exome sequencing. 50 cases classified as alveolar rhabdomyosarcoma his… (full text at CIViC) PMID 24436047 · Shern et al., 2014 · Open in CIViC | civic |